Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Piper M"'
Autor:
Samuel I. Miller, Hillary S. Hayden, Adeline M. Hajjar, Mitchell J. Brittnacher, Naseer Sangwan, Piper M. Treuting, Stacey M Meeker, Charles W. Frevert, Eli J. Weiss, Christopher E. Pope, Kevin S Mears, Anh T. Vo, Lucas R. Hoffman, Nicholas Tolley, Kyle R. Hager, Jisun Paik
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 16, Iss 1, p e1008251 (2020)
PLoS Pathogens, Vol 16, Iss 1, p e1008251 (2020)
Patients with cystic fibrosis (CF) have altered fecal microbiomes compared to those of healthy controls. The magnitude of this dysbiosis correlates with measures of CF gastrointestinal (GI) disease, including GI inflammation and nutrient malabsorptio
Autor:
Jerrold M. Ward, Cheryl L. Scudamore, Piper M. Treuting, Patricia V. Turner, Caroline J. Zeiss, Jeffrey I. Everitt, Rani S. Sellers
Publikováno v:
ILAR Journal. 59:4-12
In translational research, animal models are an important tool to aid in decision-making when taking potential therapies into human clinical trials. Recently, there have been a number of papers that have suggested limited concordance of preclinical a
Autor:
Courtney Wilkins, Annelise G. Snyder, Brian P. Daniels, Katharina Esser-Nobis, Jessica B. Graham, Kathleen Voss, Jessica M. Snyder, Piper M. Treuting, Andrew Oberst, Michael Gale, Jennifer M. Lund, Emily A. Hemann, Kathryn McGuckin Wuertz
Publikováno v:
PLoS Pathogens, Vol 15, Iss 8, p e1007899 (2019)
PLoS Pathogens
PLoS Pathogens
West Nile Virus (WNV), an emerging and re-emerging RNA virus, is the leading source of arboviral encephalitic morbidity and mortality in the United States. WNV infections are acutely controlled by innate immunity in peripheral tissues outside of the
Autor:
Nicholas Arpaia, Ioana Lia, Taylor E. Hinchliffe, Samuel Castro, Courtney Coker, Tal Danino, Piper M. Treuting, Candice Gurbatri
Immunotherapies such as checkpoint inhibitors have revolutionized cancer therapy yet lead to a multitude of immune-related adverse events, suggesting the need for more targeted delivery systems. Due to their preferential colonization of tumors and ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22c2a40ecda074b74c3e089a85611a56
https://doi.org/10.1101/562785
https://doi.org/10.1101/562785
Autor:
Krista M. D. La Perle, Claire M. Jardine, Chelsea G. Himsworth, Nicole M. Nemeth, Piper M. Treuting, Frederick A. Leighton, Jamie L. Rothenburger
To achieve a contemporary understanding of the common and rare lesions that affect wild, urban Norway rats ( Rattus norvegicus), we conducted a detailed pathology analysis of 672 rats from Vancouver, British Columbia, Canada. Grossly evident lesions,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::182e87a822dca445764ea306fbe1e9b9
https://europepmc.org/articles/PMC6838826/
https://europepmc.org/articles/PMC6838826/
Autor:
Cory Brayton, David K. Meyerholz, Kelli L. Boyd, Brad Bolon, Piper M. Treuting, Jeffrey L Everitt
Publikováno v:
ILAR journal. 59(1)
This issue of ILAR Journal focusses on pathology and pathologists in biomedical research, more specifically in preclinical translational research involving (nonhuman) animals, emphasizing academic settings. Considerations in study design and planning
Autor:
Stephen J. Galli, Asha Lahiri, Gunnar Pejler, Magnus Åbrink, Ching-Cheng Chen, Mindy Tsai, Piper M. Treuting, Eon J. Rios, Adrian M. Piliponsky
Publikováno v:
The American Journal of Pathology. 181(3):875-886
Mouse mast cell protease 4 (mMCP-4), the mouse counterpart of human mast cell chymase, is thought to have proinflammatory effects in innate or adaptive immune responses associated with mast cell activation. However, human chymase can degrade the proi
Autor:
Alevtina Gall, Piper M. Treuting, Michael Gale, Yueh Ming Loo, Daniel B. Stetson, Keith B. Elkon, Glen N. Barber
Publikováno v:
Immunity; Vol 36
Immunity
Immunity
SummaryThe type I interferon (IFN) response initiated by detection of nucleic acids is important for antiviral defense but is also associated with specific autoimmune diseases. Mutations in the human 3′ repair exonuclease 1 (Trex1) gene cause Aicar
Autor:
Anasuya Sarkar, Piper M. Treuting, Dat P. Mao, Sarah E. Warren, Mark D. Wewers, Irina A. Leaf, Monica Dors, Edward A. Miao, Alan Aderem
Publikováno v:
Nature immunology
Macrophages mediate crucial innate immune responses via caspase-1-dependent processing and secretion of interleukin 1β (IL-1β) and IL-18. Although infection with wild-type Salmonella typhimurium is lethal to mice, we show here that a strain that pe
Autor:
Aaron Arvey, Saskia Hemmers, Piper M. Treuting, Bruno Moltedo, Alexander Y. Rudensky, Shaopeng Yuan, Jesse A. Green, Nicholas Arpaia
Publikováno v:
Cell. 162(5)
SummaryRegulatory T (Treg) cells suppress immune responses to a broad range of non-microbial and microbial antigens and indirectly limit immune inflammation-inflicted tissue damage by employing multiple mechanisms of suppression. Here, we demonstrate