Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Paul A. Trainor"'
Autor:
Christopher Seidel, Lisa L. Sandell, Paul A. Trainor, Shachi Bhatt, Youngwook Ahn, Soma Dash, Robb E Krumlauf
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Frontiers in Physiology
Frontiers in Physiology
Development of the vertebrate head is a complex and dynamic process, which requires integration of all three germ layers and their derivatives. Of special importance are ectoderm-derived cells that form the cranial placodes, which then differentiate
Publikováno v:
Development
Retinoic acid (RA), a vitamin A (retinol) derivative, has pleiotropic functions during embryonic development. The synthesis of RA requires two enzymatic reactions: oxidation of retinol into retinaldehyde by alcohol dehydrogenases (ADHs) or retinol de
Autor:
Paul A. Trainor, William A. Muñoz
Publikováno v:
Methods in Molecular Biology ISBN: 9781493994113
Mammalian development occurs in utero, which makes it difficult to study the diverse morphogenetic events of neural crest cell development in vivo. Analyses of fixed samples in conjunction with histological methods to evaluate the spatiotemporal role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3297e1a1a2f6fe927a62f4c37fb748b3
https://doi.org/10.1007/978-1-4939-9412-0_9
https://doi.org/10.1007/978-1-4939-9412-0_9
Autor:
Gwenn-Aël Carré, Marianna Tedesco, Nick Warr, Angel R. Nebreda, Paul A. Trainor, Madeleine Pope, Sara Wells, Melissa Childers, Ivan del Barco Barrantes, Andy Greenfield, Pam Siggers, Rachel Brixey, Debora Bogani, Cheryl L. Scudamore, Jessica Vitos Faleato
Publikováno v:
Developmental Cell
Summary Loss of the kinase MAP3K4 causes mouse embryonic gonadal sex reversal due to reduced expression of the testis-determining gene, Sry. However, because of widespread expression of MAP3K4, the cellular basis of this misregulation was unclear. He
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0120821 (2015)
PLoS ONE
PLoS ONE, 2015, 10 (3), pp.e0120821. ⟨10.1371/journal.pone.0120821⟩
PLoS ONE, Public Library of Science, 2015, 10 (3), pp.e0120821. ⟨10.1371/journal.pone.0120821⟩
PLoS ONE
PLoS ONE, 2015, 10 (3), pp.e0120821. ⟨10.1371/journal.pone.0120821⟩
PLoS ONE, Public Library of Science, 2015, 10 (3), pp.e0120821. ⟨10.1371/journal.pone.0120821⟩
International audience; Cranial nerves govern sensory and motor information exchange between the brain and tissues of the head and neck. The cranial nerves are derived from two specialized populations of cells, cranial neural crest cells and ectoderm
Autor:
Pamela C. Yelick, Paul A. Trainor
Publikováno v:
Rare Diseases
Disruptions in ribosomal biogenesis would be expected to have global and in fact lethal effects on a developing organism. However, mutations in ribosomal protein genes have been shown in to exhibit tissue specific defects. This seemingly contradictor
Autor:
Sylvia M. Evans, Lisa L. Sandell, Xianling Zhao, Thomas J. Cunningham, Paul A. Trainor, Gregg Duester
Publikováno v:
Cell Reports, Vol 3, Iss 5, Pp 1503-1511 (2013)
SummaryThe vitamin A metabolite retinoic acid (RA) provides patterning information during vertebrate embryogenesis, but the mechanism through which RA influences limb development is unclear. During patterning of the limb proximodistal axis (upper lim
Autor:
James F. Brinkley, Axel Visel, Scott E. Fraser, Fernando Pardo-Manuel de Villena, Stephen A. Murray, Jeffrey C. Murray, Paul A. Trainor, Michael J. Dixon, Ophir D. Klein, Junichi Iwata, Bruce J. Aronow, Leah Rae Donahue, Michael L. Cunningham, John H. Postlethwait, Benedikt Hallgrímsson, Linda G. Shapiro, Terri H. Beaty, Yang Chai, Harry Hochheiser, David E. Clouthier, Seth M. Weinberg, Mary L. Marazita, Kristin Bruk Artinger, S. Steven Potter, Richard A. Spritz
The FaceBase Consortium consists of ten interlinked research and technology projects whose goal is to generate craniofacial research data and technology for use by the research community through a central data management and integrated bioinformatics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::487268b493f2675e974a97a4a3d8460d
https://resolver.caltech.edu/CaltechAUTHORS:20110718-100407556
https://resolver.caltech.edu/CaltechAUTHORS:20110718-100407556
Autor:
Olga Nikolaeva, Paul A. Trainor, Jian Xing Ma, Gennadiy Moiseyev, Krysten M. Farjo, Lisa L. Sandell
Publikováno v:
Developmental biology. 357(2)
Retinoic acid (atRA) signaling is essential for regulating embryonic development, and atRA levels must be tightly controlled in order to prevent congenital abnormalities and fetal death which can result from both excessive and insufficient atRA signa
Autor:
Eumorphia Remboutsika, Paul A. Trainor, Maria Poulou, Thimios A. Mitsiadis, Robin Lovell-Badge, Angelo Iulianella, Maximilianos Elkouris, Cynthia L. Andoniadou
Publikováno v:
Frontiers in Physiology
Frontiers in Physiology, Vol 2 (2011)
Frontiers in Physiology, Vol 2 (2011)
Embryonic cortical neural stem cells are self-renewing progenitors that can differentiate into neurons and glia. We generated neurospheres from the developing cerebral cortex using a mouse genetic model that allows for lineage selection and found tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::624be50e8aebb7443c8a199e63c8f1f0
https://doi.org/10.5167/uzh-63253
https://doi.org/10.5167/uzh-63253