Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Lucia Knopfová"'
Autor:
Sára Lenárt, Peter Lenárt, Lucia Knopfová, Hana Kotasová, Vendula Pelková, Veronika Sedláková, Vladimír Čan, Jan Šmarda, Karel Souček, Aleš Hampl, Petr Beneš
TACSTD2 encodes a transmembrane glycoprotein Trop2 commonly overexpressed in carcinomas. While the Trop2 protein was discovered already in 1981 and first antibody-drug conjugate targeting Trop2 were recently approved cancer therapy, the physiological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7f1ccc011d8be1bda0430a0a7ec71ed
https://doi.org/10.1101/2021.06.29.450320
https://doi.org/10.1101/2021.06.29.450320
Autor:
Pavel Kopel, Lukas Nejdl, Lucia Knopfová, Markéta Sztalmachová, Martina Raudenská, Marie Stiborová, Michal Masarik, Jana Vlachova, René Kizek, Michaela Fojtu, Vojtech Adam, Petr Babula, Anna Skotakova, Sylvie Skalickova, Jaromír Gumulec
Publikováno v:
International Journal of Molecular Sciences, Vol 15, Iss 12, Pp 22960-22977 (2014)
International Journal of Molecular Sciences. 2014, vol. 15, issue 12, p. 22960-22977.
International Journal of Molecular Sciences
Volume 15
Issue 12
Pages 22960-22977
International Journal of Molecular Sciences. 2014, vol. 15, issue 12, p. 22960-22977.
International Journal of Molecular Sciences
Volume 15
Issue 12
Pages 22960-22977
Doxorubicin is an effective chemotherapeutic drug, however, its toxicity is a significant limitation in therapy. Encapsulation of doxorubicin inside liposomes or ferritin cages decreases cardiotoxicity while maintaining anticancer potency. We synthes
Autor:
Michal Masarik, Veronika Dvorakova, Martina Raudenská, Hana Polanska, René Kizek, Vojtech Adam, Jaromír Gumulec, Kristyna Hudcova, Lucia Knopfová, Jan Balvan, Petr Babula, Branislav Ruttkay-Nedecky, Marie Stiborová, Markéta Sztalmachová
Publikováno v:
International Journal of Oncology. 44:923-933
Differences in the antioxidant system, apoptotic mechanism and in cell cycle between prostatic cell lines could partially elucidate the development of cisplatin resistance. The aim of this study was to identify the most characteristic parameter for a
Publikováno v:
Cellular Signalling. 25:1546-1555
Nuclear factors of activated T-cells (NFATs) are important regulators of the cytokine gene expression in activated T-cells. In the last decade, NFATs have been shown to regulate cell cycle, differentiation and apoptosis in cells of various origins re
Autor:
Lucia Knopfová, Vlasta Lungová, Eva Matalová, Jan Šmarda, Marcela Buchtová, Eva Janečková, Abigail S. Tucker
Publikováno v:
European Journal of Oral Sciences. 120:495-504
The MYB family of transcription activators has been associated with a high proliferation rate and an undifferentiated state of cells in a number of tissues. Recently emerging data suggest that these molecules may also play a role in differentiation.
Publikováno v:
Environmental and Molecular Mutagenesis. 53:515-524
Wedelolactone is one of the active plant polyphenolic compounds. Anti-tumor effects of this drug have been demonstrated recently. We have described that wedelolactone acts as catalytic inhibitor of DNA topoisomerase IIα. The aim of this study was to
Autor:
Jan Šmarda, Lucia Knopfová
Publikováno v:
Experimental and Therapeutic Medicine. 1:257-264
Increased production of the pro-inflammatory enzyme cyclooxygenase-2 (Cox-2) and altered expression and activity of peroxisome proliferator-activated receptor γ (PPARγ) have been observed in many malignancies. Both the PPARγ ligands and the Cox-2
Autor:
Lucia Knopfová, Miroslav Fojta, Diana Pinheiro, Filip Trčka, Karel Souček, Petr Beneš, Alice Nemajerova, Jan Šmarda
Publikováno v:
Cancer letters. 303(1)
The naturally occurring coumestan wedelolactone has been previously shown to reduce growth of various cancer cells. So far, the growth-suppressing effect of wedelolactone has been attributed to the inhibition of the NFκB transcription factor and/or
Autor:
Lucia Knopfová, Helena Polakova, Jan Šmarda, Radek Zboril, Eva Gabrielová, Ivan Justan, Fabio Vianello, Josef Skopalik, Massimiliano Magro, Katerina Polakova, Markéta Havrdová, David Milde, Jaroslav Michálek
Publikováno v:
International Journal of Nanomedicine
Josef Skopalik,1 Katerina Polakova,2 Marketa Havrdova,2 Ivan Justan,1 Massimiliano Magro,3 David Milde,2 Lucia Knopfova,4 Jan Smarda,4 Helena Polakova,1 Eva Gabrielova,5 Fabio Vianello,2,3 Jaroslav Michalek,1 Radek Zboril21Department of Pharmacology,