Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Jeremie Boucher"'
Autor:
Ida Alexandersson, Nahida Arifen, Firoozeh Salehzadeh, Anders Thorell, Carolina E. Hagberg, Jeremie Boucher, Kirsty L. Spalding, Qian Li, Ping Chen, Niels Krämer, Matthew J. Harms, Carole Knibbe, Shuai Lang, Helena Silva Cascales, Eleni Terezaki, Mervi T. Hyvönen, Myriam Aouadi, Maria Kutschke
Publikováno v:
Nature Medicine
Nature Medicine, 2021, 27 (11), pp.1941-1953. ⟨10.1038/s41591-021-01501-8⟩
Nature Medicine, Nature Publishing Group, 2021, 27 (11), pp.1941-1953. ⟨10.1038/s41591-021-01501-8⟩
Nature Medicine, 2021, 27 (11), pp.1941-1953. ⟨10.1038/s41591-021-01501-8⟩
Nature Medicine, Nature Publishing Group, 2021, 27 (11), pp.1941-1953. ⟨10.1038/s41591-021-01501-8⟩
International audience; Obesity is considered an important factor for many chronic diseases, including diabetes, cardiovascular disease and cancer. The expansion of adipose tissue in obesity is due to an increase in both adipocyte progenitor differen
Autor:
Nils-Göran Larsson, Olivier Bezy, Cristina M. Zingaretti, Kevin Y. Lee, Arnaud Mourier, Graham Smyth, C. Ronald Kahn, Cecile Vernochet, Ding An, Jeremie Boucher, Matthew J. Rardin, Olga Ilkayeva, Yazmín Macotela, Bradford W. Gibson, Brice Emanuelli, Christopher B. Newgard, Saverio Cinti
Publikováno v:
Cell Metabolism; Vol 16
Cell Metab
Cell Metab
SummaryObesity and type 2 diabetes are associated with mitochondrial dysfunction in adipose tissue, but the role for adipose tissue mitochondria in the development of these disorders is currently unknown. To understand the impact of adipose tissue mi
Autor:
Rohit N. Kulkarni, Cristina Mallol, Yu-Hua Tseng, Alessandro Doria, Jit Kong Cheong, Cecile Vernochet, Jeremie Boucher, Ho-Jin Koh, Jiang Hu, Dan Kawamori, Matthias Blüher, Stephen I-Hong Hsu, Kristy L. Townsend, Marc K. Hellerstein, Chong Wee Liew, Stephen R. Farmer, Dominique Langin, Laurie J. Goodyear
Publikováno v:
Nature medicine
Obesity develops as a result of altered energy homeostasis favoring fat storage. Here we describe a new transcription co-regulator for adiposity and energy metabolism, SERTA domain containing 2 (TRIP-Br2, also called SERTAD2). TRIP-Br2-null mice are
Autor:
Matthias Blüher, Yazmín Macotela, Michael Rourk, C. Ronald Kahn, Kevin Y. Lee, Marcelo A. Mori, Steven Russell, Graham Smyth, Chong Wee Liew, Jeremie Boucher
Publikováno v:
Nature communications
Insulin and insulin-like growth factor 1 (IGF-1) have important roles in adipocyte differentiation, glucose tolerance and insulin sensitivity. Here to assess how these pathways can compensate for each other, we created mice with a double tissue-speci
Autor:
James L. Kirkland, Marcelo A. Mori, Stacey Robida-Stubbs, Steven Russell, C. Ronald Kahn, Thomas Thomou, Jeremie Boucher, Prashant Raghavan, Yazmín Macotela, T. Keith Blackwell
Publikováno v:
Cell metabolism. 16(3)
SummaryExcess adipose tissue is associated with metabolic disease and reduced life span, whereas caloric restriction decreases these risks. Here we show that as mice age, there is downregulation of Dicer and miRNA processing in adipose tissue resulti
SummaryIn obesity, adipocytes distant from vasculature become hypoxic and dysfunctional. This hypoxic response is mediated by hypoxia-inducible factors (Hif1α, Hif2α, and Hif3α) and their obligate partner, Hif1β (Arnt). We show that mice lacking
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e99fc36ceb94c77e5c953a6289ccd415
https://europepmc.org/articles/PMC3206000/
https://europepmc.org/articles/PMC3206000/
Autor:
C. Ronald Kahn, Brice Emanuelli, Kirk Beebe, Daniel Espinoza, Walter Gall, Anneli M. Bång, Jeremie Boucher, Yazmín Macotela
Publikováno v:
PLoS ONE
PLoS ONE, Vol 6, Iss 6, p e21187 (2011)
PLoS ONE, Vol 6, Iss 6, p e21187 (2011)
Environmental factors, such as the macronutrient composition of the diet, can have a profound impact on risk of diabetes and metabolic syndrome. In the present study we demonstrate how a single, simple dietary factor--leucine--can modify insulin resi
Publikováno v:
Diabetes
OBJECTIVE To investigate how insulin sensitivity and glucose metabolism differ in adipocytes between different fat depots of male and female mice and how sex steroids contribute to these differences. RESEARCH DESIGN AND METHODS Adipocytes from intra-
Autor:
Philippe Valet, Marie-Noëlle Monthouël-Kartmann, Isabelle Castan-Laurell, Emmanuel Van Obberghen, Jeremie Boucher, Sophie Tartare-Deckert, E. Helene Sage, Carine Chavey
Publikováno v:
Obesity
Obesity, Wiley, 2006, 14 (11), pp.1890-1897. ⟨10.1038/oby.2006.220⟩
Obesity, Wiley, 2006, 14 (11), pp.1890-1897. ⟨10.1038/oby.2006.220⟩
Objective: To explore the regulation of secreted protein acidic and rich in cysteine (SPARC) expression and its role in adipose tissue. Research Methods and Procedures: We studied the regulation of SPARC expression in transgenic mice expressing the h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::894be6cb261f94e759c3215d8507ff05
https://hal.archives-ouvertes.fr/hal-03066287
https://hal.archives-ouvertes.fr/hal-03066287
Autor:
Christian Carpéné, Philippe Valet, Charlotte Guigné, J. P. Pradères, Didier Quilliot, Gilles Ferry, Jean A. Boutin, Jean Sébastien Saulnier-Blache, Marie-Françoise Simon, Jeremie Boucher, D. Prévot, Sandra Grès
Publikováno v:
Diabetologia
Diabetologia, 2005, 48 (3), pp.569-77. ⟨10.1007/s00125-004-1660-8⟩
Diabetologia, Springer Verlag, 2005, 48 (3), pp.569-77. ⟨10.1007/s00125-004-1660-8⟩
Diabetologia, 2005, 48 (3), pp.569-77. ⟨10.1007/s00125-004-1660-8⟩
Diabetologia, Springer Verlag, 2005, 48 (3), pp.569-77. ⟨10.1007/s00125-004-1660-8⟩
AIMS/HYPOTHESIS: Autotaxin is a lysophospholipase D that is secreted by adipocytes and whose expression is substantially up-regulated in obese, diabetic db/db mice. The aim of the present study was to depict the physiopathological and cellular mechan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f431589051e692f4dbcc60969025f19a
https://www.hal.inserm.fr/inserm-00110116
https://www.hal.inserm.fr/inserm-00110116