Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Barbara McKnight"'
Autor:
Chani J. Hodonsky, Antoine R Baldassari, Colleen M. Sitlani, Christy L. Avery, Barbara McKnight, Heather M. Highland
Publikováno v:
Hum Mol Genet
Genome-wide association studies have been successful mapping loci for individual phenotypes, but few studies have comprehensively interrogated evidence of shared genetic effects across multiple phenotypes simultaneously. Statistical methods have been
Autor:
Mariaelisa Graff, Zhaoming Wang, David R. Weir, Ann W. Hsing, Joel N. Hirschhorn, Rebecca S. Fine, Wei Zheng, William Maixner, Adebowale Adeyemo, Rick A. Kittles, Rebecca Rohde, Krista A. Zanetti, Elizabeth K. Speliotes, Keri L. Monda, Ingrid B. Borecki, Yaming Shao, Suhn K. Rhie, Sanjay R. Patel, Richard S. Cooper, Jerome I. Rotter, Michael J. Thun, William J. Blot, Brendan J. Keating, Michèle M. Sale, Scott M. Williams, Yingchang Lu, Margaret A. Tucker, Eric A. Klein, Uma Nayak, Curtis A. Pettaway, Yii-Der Ida Chen, Sailaja Vedantam, Pamela J. Schreiner, Phyllis J. Goodman, Babatunde L. Salako, Christine Neslund-Dudas, Andrew B. Singleton, Michael F. Press, Neil E. Caporaso, Maureen Sanderson, Diane M. Becker, Michele K. Evans, Margaret R. Spitz, Christopher I. Amos, Susan Redline, Kurt Lohman, Ching-Ti Liu, Hampton L. Leonard, Kris Monroe, Sun J. Kang, David Van Den Berg, Janet L. Stanford, Lewis H. Kuller, Traci M. Bartz, J. M. Zmuda, Christopher S. Carlson, Ruth J. F. Loos, Joanne M. Jordan, Guillaume Lettre, Youfang Liu, Lara Sucheston, Mike A. Nalls, Shad B. Smith, Suzanne Kolb, Lisa B. Signorello, Daniel Shriner, Tamara B. Harris, Larry D. Atwood, Wei-Min Chen, Oladosu Ojengbede, Kristin A. Rand, Claudia Schurmann, Guanjie Chen, Sharon L.R. Kardia, Graham Casey, Lawrence F. Bielak, Dena G. Hernandez, Talin Haritunians, Rajiv Nadukuru, Elisa V. Bandera, Matthew A. Allison, Amidou N'Diaye, Donna K. Arnett, Olufunmilayo I. Olopade, Ellen W. Demerath, Babette S. Zemel, Margaret Wrensch, Myriam Fornage, John K. Wiencke, George J. Papanicolaou, Sara S. Strom, Temidayo O. Ogundiran, Gregory L. Burke, Erin B. Ware, Marian L. Neuhouser, James G. Wilson, Dhananjay Vaidya, Nicholette D. Palmer, Marguerite R. Irvin, JoAnn E. Manson, Benjamin A. Rybicki, Laurence N. Kolonel, Chad D. Huff, Jennifer J. Hu, Jennifer A. Brody, L. Keoki Williams, Leslie A. Lange, Qing Duan, David S. Siscovick, Yongmei Liu, Leslie Bernstein, Jennifer A. Smith, Latchezar Dimitrov, Sarah J. Nyante, Sue A. Ingles, Yu Han H. Hsu, Xifeng Wu, Heather M. Ochs-Balcom, Jingzhong Ding, David V. Conti, L. Adrienne Cupples, Gerry A. Coetzee, Thomas H. Mosley, Kristin L. Young, Donald W. Bowden, Edmond K. Kabagambe, Christine B. Ambrosone, Karen C. Johnson, Patricia A. Peyser, Stefan Ambs, Victoria L. Stevens, Minhui Chen, Carl D. Langefeld, Sonja I. Berndt, Andrew F. Olshan, Qiuyin Cai, Jessica D. Faul, Mary F. Feitosa, Brian E. Cade, Esther M. John, Ann G. Schwartz, Yan V. Sun, Xinruo Zhang, Stephen J. Chanock, Jason H. Moore, Alexander P. Reiner, Caroline S. Fox, Charles Kooperberg, Anne E. Justice, Jin Li, Lorna H. McNeill, Alex Stram, Jie Yao, Xiuqing Guo, Mara Z. Vitolins, Edward A. Ruiz-Narváez, Abdullah Kutlar, Charleston W. K. Chiang, Jing Hua Zhao, Lisa R. Yanek, Poorva Mudgal, John D. Carpten, Barbara V. Howard, Anselm Hennis, Charles N. Rotimi, Ulrich Broeckel, Albert M. Levin, Jonathan P. Bradfield, Curtis C. Harris, Regina G. Ziegler, Brian E. Henderson, Bruce M. Psaty, Adeyinka G. Falusi, Katherine L. Nathanson, Barbara McKnight, Melinda C. Aldrich, Herman A. Taylor, Melissa Garcia, Degui Zhi, Dezheng Huo, Barry I. Freedman, D. C. Rao, Sylvia Wassertheil-Smoller, Jie Zhou, Adam B. Murphy, Eric E. Schadt, Sandra L. Deming, John S. Witte, Julie R. Palmer, Neil A. Zakai, Adesola Ogunniyi, Yun Li, Mary Cushman, Victoria L. Buchanan, Jorge L. Rodriguez-Gil, Struan F.A. Grant, Timothy D. Howard, Omri Gottesman, Wei Zhao, Kira C. Taylor, Yan Meng, Hayrettin Okut, Hakon Hakonarson, Xiaofeng Zhu, Elizabeth M. Gillanders, Alan B. Zonderman, Lisa Chu, Badri Padhukasahasram, Vaneet Lotay, W. Ryan Diver, Mary K. Wojczynski, Simin Liu, Erwin P. Bottinger, Cameron D. Palmer, Alessandra Chesi, Elise Lim, Laura J. Rasmussen-Torvik, Eirini Marouli, Kari E. North, Salman M. Tajuddin, Christopher A. Haiman, Barbara Nemesure, Loic Le Marchand, Bamidele O. Tayo, Maggie C.Y. Ng
Publikováno v:
Am J Hum Genet
Although many loci have been associated with height in European ancestry populations, very few have been identified in African ancestry individuals. Furthermore, many of the known loci have yet to be generalized to and fine-mapped within a large-scal
Autor:
Colleen M. Sitlani, Nels C. Olson, Joseph A.C. Delaney, Barbara McKnight, Margaret F. Doyle, Sally A. Huber, Kenneth Rice, Thomas Lumley, Russell P. Tracy, Bruce M. Psaty
Publikováno v:
BMC Medical Research Methodology
BMC Medical Research Methodology, Vol 20, Iss 1, Pp 1-10 (2020)
BMC Medical Research Methodology, Vol 20, Iss 1, Pp 1-10 (2020)
Background Cox proportional hazards regression models are used to evaluate associations between exposures of interest and time-to-event outcomes in observational data. When exposures are measured on only a sample of participants, as they are in a cas
Autor:
Barbara McKnight, Theresa Aliwarga, Eric A. Evangelista, Paul N. Jensen, Nona Sotoodehnia, Rheem A. Totah, Sina A. Gharib, Rozenn N. Lemaitre
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
CYP2J2, a member of the Cytochrome P450 family of enzymes, is the most abundant epoxygenase in the heart and has multifunctional properties including bioactivation of arachidonic acid to epoxyeicosatrienoic acids, which, in turn, have been implicated
Autor:
Paul N. Jensen, Colleen M. Sitlani, Susan R. Heckbert, Amanda M. Fretts, Irena B. King, Rozenn N. Lemaitre, Dariush Mozaffarian, Andrew N. Hoofnagle, Nona Sotoodehnia, Barbara McKnight, Bruce M. Psaty, David S. Siscovick
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Ceramides exhibit multiple biological activities that may influence the pathophysiological characteristics of atrial fibrillation (AF). Whether the length of the saturated fatty acid carried by the ceramide or their sphingomyelin precursor
Autor:
Xiaoling Song, Amanda R. Vest, Barbara McKnight, Yujin Lee, Rozenn N. Lemaitre, Dariush Mozaffarian, Heidi Lai, Irena B. King, Gordon S. Huggins, Marcia C de Oliveira Otto, David S. Siscovick
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background De novo lipogenesis ( DNL ) is an endogenous pathway that converts excess dietary starch, sugar, protein, and alcohol into specific fatty acids ( FA s). Although elevated DNL is linked to several metabolic abnormalities, little is known ab
Autor:
Barbara McKnight, Martina Müller-Nurasyid, Raha Pazoki, Michael W.T. Tanck, Thomas Engstrøm, Arthur A.M. Wilde, Man Li, Martin VanDenburgh, Marieke T. Blom, Reza Jabbari, Thomas Meitinger, Philippe Goyette, Anna Moes, Rebecca N. Mitchell, Christine M. Albert, Aravinda Chakravarti, Dan E. Arking, Jean-Claude Tardif, Rozenn N. Lemaitre, Foram N. Ashar, Pui-Yan Kwok, Frank D. Kolodgie, Jacob Tfelt-Hansen, Renu Virmani, Susan R. Heckbert, Angel C.Y. Mak, David S. Siscovick, Vinicius Tragante, Xavier Jouven, Hanno L. Tan, John D. Rioux, Mark Eijgelsheim, Ronald J. Prineas, Nona Sotoodehnia, Xiaoqing Zhao, Stefan A. Escher, Heikki V. Huikuri, Bruce M. Psaty, Charlotte Glinge, Albert Hofman, Oscar H. Franco, Florence Dumas, Bruno H. Stricker, M. Juhani Junttila, Folkert W. Asselbergs, Josef Coresh, Christopher J. O'Donnell, Paul W. Franks, Shih-Jen Hwang, Veikko Salomaa, Jan-Håkan Jansson, Stefan Kääb, Christopher Newton-Cheh, Joseph J. Maleszewski, Paul I.W. de Bakker, Jennifer A. Brody, Aki S. Havulinna, André G. Uitterlinden, Georg Ehret, Jerome I. Rotter, Thomas Lumley, Connie R. Bezzina, Marc K. Halushka, Sara L. Pulit
Publikováno v:
Ashar, F N, Mitchell, R N, Albert, C M, Newton-Cheh, C, Brody, J A, Müller-Nurasyid, M, Moes, A, Meitinger, T, Mak, A, Huikuri, H, Junttila, M J, Goyette, P, Pulit, S L, Pazoki, R, Tanck, M W, Blom, M T, Zhao, X, Havulinna, A S, Jabbari, R, Glinge, C, Tragante, V, Escher, S A, Chakravarti, A, Ehret, G, Coresh, J, Li, M, Prineas, R J, Franco, O H, Kwok, P Y, Lumley, T, Dumas, F, McKnight, B, Rotter, J I, Lemaitre, R N, Heckbert, S R, O'Donnell, C J, Hwang, S J, Tardif, J C, VanDenburgh, M, Uitterlinden, A G, Hofman, A, Stricker, B H C, De Bakker, P I W, Franks, P W, Jansson, J H, Asselbergs, F W, Halushka, M K, Maleszewski, J J, Tfelt-Hansen, J, Engstrøm, T, Salomaa, V, Virmani, R, Kolodgie, F, Wilde, A A M, Tan, H L, Bezzina, C R, Eijgelsheim, M, Rioux, J D, Jouven, X, Kääb, S, Psaty, B M, Siscovick, D S, Arking, D E & Sotoodehnia, N 2018, ' A comprehensive evaluation of the genetic architecture of sudden cardiac arrest ', European Heart Journal, vol. 39, no. 44, pp. 3961-3969 . https://doi.org/10.1093/eurheartj/ehy474
European Heart Journal
European Heart Journal, 39(44), 3961. Oxford University Press
Ashar, Foram N; Mitchell, Rebecca N; Albert, Christine M; Newton-Cheh, Christopher; Brody, Jennifer A; Müller-Nurasyid, Martina; Moes, Anna; Meitinger, Thomas; Mak, Angel; Huikuri, Heikki; Junttila, M Juhani; Goyette, Philippe; Pulit, Sara L; Pazoki, Raha; Tanck, Michael W; Blom, Marieke T; Zhao, XiaoQing; Havulinna, Aki S; Jabbari, Reza; Glinge, Charlotte; ... (2018). A comprehensive evaluation of the genetic architecture of sudden cardiac arrest. European Heart Journal, 39(44), pp. 3961-3969. Oxford University Press 10.1093/eurheartj/ehy474
European Heart Journal, 39(44), 3961-3969. Oxford University Press
European Heart Journal, 39(44), 3961-+. Oxford University Press
European Heart Journal, Vol. 39, No 44 (2018) pp. 3961-3969
European heart journal, vol 39, iss 44
European heart journal, 39(44), 3961-3969. Oxford University Press
European Heart Journal
European Heart Journal, 39(44), 3961. Oxford University Press
Ashar, Foram N; Mitchell, Rebecca N; Albert, Christine M; Newton-Cheh, Christopher; Brody, Jennifer A; Müller-Nurasyid, Martina; Moes, Anna; Meitinger, Thomas; Mak, Angel; Huikuri, Heikki; Junttila, M Juhani; Goyette, Philippe; Pulit, Sara L; Pazoki, Raha; Tanck, Michael W; Blom, Marieke T; Zhao, XiaoQing; Havulinna, Aki S; Jabbari, Reza; Glinge, Charlotte; ... (2018). A comprehensive evaluation of the genetic architecture of sudden cardiac arrest. European Heart Journal, 39(44), pp. 3961-3969. Oxford University Press 10.1093/eurheartj/ehy474
European Heart Journal, 39(44), 3961-3969. Oxford University Press
European Heart Journal, 39(44), 3961-+. Oxford University Press
European Heart Journal, Vol. 39, No 44 (2018) pp. 3961-3969
European heart journal, vol 39, iss 44
European heart journal, 39(44), 3961-3969. Oxford University Press
BackgroundSudden cardiac arrest (SCA) accounts for 10% of adult mortality in Western populations. While several risk factors are observationally associated with SCA, the genetic architecture of SCA in the general population remains unknown. Furthermo
Autor:
Paul N. Jensen, Rozenn N. Lemaitre, Dariush Mozaffarian, Susan R. Heckbert, Andrew N. Hoofnagle, Nona Sotoodehnia, David S. Siscovick, Amanda M. Fretts, Bruce M. Psaty, Irena B. King, Barbara McKnight
Publikováno v:
Circulation: Heart Failure. 12
Background: Ceramides exhibit multiple biological activities that may influence the pathophysiology of heart failure. These activities may be influenced by the saturated fatty acid carried by the ceramide (Cer). However, the associations of different
Autor:
Matti Marklund, Sari Voutilainen, Claudine Berr, Nicholas J. Wareham, Dariush Mozaffarian, Albert Koulman, Cécilia Samieri, Ingeborg A. Brouwer, Jenna Veenstra, Amanda M. Fretts, Luc Djoussé, David S. Siscovick, V. Gudnason, Lynne E. Wagenknecht, Lyn M. Steffen, Maria Lankinen, Michael Y. Tsai, Nathan L. Tintle, Nona Sotoodehnia, Jyrki K. Virtanen, Fumiaki Imamura, Barbara McKnight, Catherine Helmer, Kuo-Liong Chien, Kerry L. M. Wong, Jason H Y Wu, Rozenn N. Lemaitre, Bill Harris, Chaoyu Yu, Renata Micha, Matti Uusitupa, Tamara B. Harris, Kalina Rajaobelina, Nita G. Forouhi, Alexis C. Wood, Waqas Qureshi, Rachel A. Murphy, Markku Laakso, Brian T. Steffen, Anya Kalsbeek
Publikováno v:
InterAct Consortium 2019, ' Associations of circulating very-long-chain saturated fatty acids and incident type 2 diabetes : a pooled analysis of prospective cohort studies ', The American journal of clinical nutrition, vol. 109, no. 4, pp. 1216-1223 . https://doi.org/10.1093/ajcn/nqz005
American Journal of Clinical Nutrition
American Journal of Clinical Nutrition, American Society for Nutrition, 2019, 109 (4), pp.1216-1223. ⟨10.1093/ajcn/nqz005⟩
The American Journal of Clinical Nutrition
The American Journal of Clinical Nutrition, Oxford University Press, 2019, 109 (4), pp.1216-1223. ⟨10.1093/ajcn/nqz005⟩
The American journal of clinical nutrition, 109(4), 1216-1223. Oxford University press
American Journal of Clinical Nutrition
American Journal of Clinical Nutrition, American Society for Nutrition, 2019, 109 (4), pp.1216-1223. ⟨10.1093/ajcn/nqz005⟩
The American Journal of Clinical Nutrition
The American Journal of Clinical Nutrition, Oxford University Press, 2019, 109 (4), pp.1216-1223. ⟨10.1093/ajcn/nqz005⟩
The American journal of clinical nutrition, 109(4), 1216-1223. Oxford University press
International audience; BACKGROUND:Saturated fatty acids (SFAs) of different chain lengths have unique metabolic and biological effects, and a small number of recent studies suggest that higher circulating concentrations of the very-long-chain SFAs (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd97a8e8e84453a060609f378434909d
https://hdl.handle.net/1871.1/02c70c2f-2fd8-4702-a8dc-cf15788bed7c
https://hdl.handle.net/1871.1/02c70c2f-2fd8-4702-a8dc-cf15788bed7c
Autor:
Shafqat Ahmad, Christina M Astley, Ruth J. F. Loos, Evangelos Evangelou, M. Fabiola Del Greco, Barbara McKnight, Helen R. Warren, Sonja I. Berndt, Carolina Medina-Gomez, Eirini Marouli, Jana V. van Vliet-Ostaptchouk, Joel N. Hirschhorn, Panos Deloukas, Zhihong Zhu, Mark J. Caulfield, Zoltán Kutalik, Jian Yang
Publikováno v:
Communications Biology, Vol 2, Iss 1, Pp 1-9 (2019)
Communications biology, 2:119. Nature Publishing Group
Communications Biology
Communications biology, vol. 2, pp. 119
Communications Biology, 2:119. Springer Nature
Communications biology, 2:119. Nature Publishing Group
Communications Biology
Communications biology, vol. 2, pp. 119
Communications Biology, 2:119. Springer Nature
There is evidence that lower height is associated with a higher risk of coronary artery disease (CAD) and increased risk of type 2 diabetes (T2D). It is not clear though whether these associations are causal, direct or mediated by other factors. Here