Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Ansuman T. Satpathy"'
Autor:
Howard Y. Chang, Peng Xu, Kevin R. Parker, Thomas J. Wandless, Zinaida Good, Elena Sotillo, Hima Anbunathan, Yanyan Qi, Robbie G. Majzner, Panayiotis Vandris, Ansuman T. Satpathy, Ling-chun Chen, Rachel C. Lynn, Crystal L. Mackall, Evan W. Weber, Andrew J. Gentles, Meena Malipatlolla, John Lattin
SUMMARYT cell exhaustion limits immune responses against cancer and is a major cause of resistance to CAR-T cell therapeutics. Using a model wherein tonic CAR signaling induces hallmark features of exhaustion, we employed a drug-regulatable CAR to te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62d0cb492f502fad83e1351f817e8403
https://doi.org/10.1101/2020.01.26.920496
https://doi.org/10.1101/2020.01.26.920496
Autor:
William J. Greenleaf, Jean Wang, Darisha Jhutty, Grace X.Y. Zheng, Kathryn E. Yost, Yifeng Yin, Preyas Shah, Corey M. Nemec, Ansuman T. Satpathy, Li Wang, Francesca Meschi, M. Ryan Corces, Howard Y. Chang, Jason C. Bell, Jeffrey M. Granja, Geoffrey P. McDermott, Paul G. Giresi, Anne Lynn S. Chang, Yanyan Qi, Brett N. Olsen, Maxwell R. Mumbach, Sarah E. Pierce
Publikováno v:
Nat Biotechnol
Understanding complex tissues requires single-cell deconstruction of gene regulation with precision and scale. Here we present a massively parallel droplet-based platform for mapping transposase-accessible chromatin in tens of thousands of single cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db0cb42476cb5620faa7fa1f6a0f5a06
Autor:
Neil E. Wilson, Aparna Bhaduri, Fang Liu, Ansuman T. Satpathy, Howard Y. Chang, Eric Perkey, Khatuna Gabunia, John Scholler, Ivan Maillard, Thomas J. Montine, Arnold R. Kriegstein, Avery D. Posey, Vijay Bhoj, Denis Migliorini, Ravinder Reddy, Carl H. June, Mohammad Haris, Kevin R. Parker, Puneet Bagga, Kathryn E. Yost, Suyash Mohan
Publikováno v:
Cell, Vol. 183, No 1 (2020) pp. 126-142.e17
Cell, vol 183, iss 1
Cell
Cell, vol 183, iss 1
Cell
CD19-directed immunotherapies are clinically effective for treating B cell malignancies but also cause a high incidence of neurotoxicity. A subset of patients treated with chimeric antigen receptor (CAR) Tcells or bispecific Tcell engager (BiTE) anti