Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Nicholas J. Agard"'
Autor:
Alberto Estevez, Sharmila Rajan, John Ridgway Brady, Henry Chiu, Phil Hass, Claudio Ciferri, Greg A. Lazar, Amin Famili, Brandon Leonard, Nicholas J. Agard, Julie A. Zorn, Susan Crowell, Yvonne Chen, Marissa L. Matsumoto, Maciej Paluch, Wilson Phung, Minhong Yan
Publikováno v:
mAbs
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Treatment of ocular disease is hindered by the presence of the blood-retinal barrier, which restricts access of systemic drugs to the eye. Intravitreal injections bypass this barrier, delivering high concentrations of drug to the targeted tissue. How
Autor:
Kenichi Shimada, Arnold L. Rheingold, Kazutaka Shimbo, Nicholas J. Agard, Vincent J. Venditto, Olivier Julien, Jonathan S. Weissman, Brent R. Stockwell, Julie A. Zorn, Michael C. Bassik, James A. Wells, Martin Kampmann
Publikováno v:
Nature chemical biology
We previously discovered a small-molecule inducer of cell death, named 1541, that noncovalently self-assembles into chemical fibrils ('chemi-fibrils') and activates procaspase-3 in vitro. We report here that 1541-induced cell death is caused by the f
Autor:
Nicholas J. Agard, Carolyn R. Bertozzi
Publikováno v:
Accounts of Chemical Research
Glycosylation is an essential form of post-translational modification that regulates intracellular and extracellular processes. Regrettably, conventional biochemical and genetic methods often fall short for the study of glycans, because their structu