Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Kathryn A. Hanley"'
Autor:
Shannan L. Rossi, Steven G. Widen, Kathryn A. Hanley, Jeffrey B. Arterburn, Ramesh Chinnasamy, Stacey L P Scroggs, Nikos Vasilakis, Sasha R. Azar, Jordan T. Gass
Drugs against flaviviruses such as dengue (DENV) and Zika (ZIKV) virus are urgently needed. We previously demonstrated that three fluoroquinolones, ciprofloxacin, enoxacin, and difloxacin, suppress replication of six flaviviruses. To investigate the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecc3959a8b22e8c2089d27ab87665464
Publikováno v:
Journal of Genomics
In the CRISPR-Cas systems, Cas13a is an RNA-guided RNA nuclease specifically targeting single strand RNA. We developed a Cas13a mediated CRISPR interference tool to target mRNA for gene silencing in mosquitoes. A Cas13a expressing plasmid was deliver
Autor:
Stacey L P Scroggs, Johnny Sena, Darci R. Smith, Nathan D. Grubaugh, Gregory D. Ebel, Faye D. Schilkey, Kathryn A. Hanley, Anitha Sundararajan
Publikováno v:
mSphere
mSphere, Vol 4, Iss 3 (2019)
mSphere, Vol 4, Iss 3, p e00291-19 (2019)
mSphere, Vol 4, Iss 3 (2019)
mSphere, Vol 4, Iss 3, p e00291-19 (2019)
The enzymes that copy RNA genomes lack proofreading, and viruses that possess RNA genomes, such as West Nile virus, rapidly diversify into swarms of mutant lineages within a host. Intrahost variation of the primary genomic sequence of RNA viruses has
Autor:
Julia Vulcan, Yashoda Kandel, Kathryn A. Hanley, Jiannong Xu, Sandra D. Melman, Emily Moore, Stacy D. Rodriguez, Kalli J. L. Martinez, Paul Ettestad, Joel J. Cordova, Michaela Buenemann, Soumi Mitra, Hae-Na Chung, Aditi Kulkarni, Immo A. Hansen, Alex S. Moon
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0212693 (2019)
PLoS ONE
PLoS ONE
BackgroundAedes aegypti mosquitoes are vectors of a variety of emerging viral pathogens, including yellow fever, dengue, chikungunya, and Zika virus. This species has established endemic populations in all cities across southern New Mexico sampled to
Autor:
Rui-de Xue, Immo A. Hansen, Ajit K. Karna, Paul Ettestad, Michaela Buenemann, Concepcion Sanchez, Sandra D. Melman, Dagne Duguma, Wanqin Yu, Aditi Kulkarni, Kathryn A. Hanley, Jiannong Xu, Kalli J. L. Martinez, Mustapha Debboun, Jinjin Jiang
Publikováno v:
Ecology and Evolution
Ecology and Evolution, Vol 9, Iss 10, Pp 6148-6156 (2019)
Ecology and Evolution, Vol 9, Iss 10, Pp 6148-6156 (2019)
The mosquitoesAedes aegypti(L.) andAe. albopictusSkuse are the major vectors of dengue, Zika, yellow fever and chikungunya viruses worldwide.Wolbachia, an endosymbiotic bacterium present in many insects, is being utilized in novel vector control stra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca4f33522debe8daec71a27d28054d06
https://doi.org/10.1101/455014
https://doi.org/10.1101/455014
Autor:
Federico Valdez, Julienne Salvador, Douglas M. Watts, Pedro M. Palermo, Kathryn A. Hanley, Jonathon E. Mohl, Manuel Llano
Schlafen 11 (Slfn11) is a ubiquitously expressed interferon stimulating gene (ISG) that controls synthesis of proteins by regulating tRNA abundance. Likely through this mechanism, Slfn11 has previously been shown to impair human immunodeficiency viru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aef5e403587731b7f839749f46f973fa
Publikováno v:
Evolutionary Applications. 2:24-31
Two or more viruses infecting the same host cell can interact in ways that profoundly affect disease dynamics and control, yet the factors determining coinfection rates are incompletely understood. Previous studies have focused on the mechanisms that
Autor:
Stephen S. Whitehead, Ethan Weinberg, Amadou A. Sall, Christopher T. Hanson, Eric B. Fokam, Scott C. Weaver, Nikos Vasilakis, Kathryn A. Hanley
Publikováno v:
Virology. 377(2):296-307
The four serotypes of endemic dengue viruses (DENV) circulate between humans and peridomestic Aedes mosquitoes. At present endemic DENV infect 100 million people per year, and a third of the global population is at risk. In contrast, sylvatic DENV st
Autor:
Scott C. Weaver, Ibrahima Dia, Douglas M. Watts, Kathryn A. Hanley, Rubing Chen, Amadou A. Sall, Diawo Diallo, Michaela Buenemann, Oumar Faye, Cheikh Tidiane Diagne, Ousmane Faye, Yamar Ba, Mawlouth Diallo
Publikováno v:
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 6, Iss 6, p e1649 (2012)
PLoS Neglected Tropical Diseases, Vol 6, Iss 6, p e1649 (2012)
The risk of human infection with sylvatic chikungunya (CHIKV) virus was assessed in a focus of sylvatic arbovirus circulation in Senegal by investigating distribution and abundance of anthropophilic Aedes mosquitoes, as well as the abundance and dist
Publikováno v:
BMC Microbiology, Vol 8, Iss 1, p 28 (2008)
BMC Microbiology
BMC Microbiology
Background Within-host competition between strains of a vector-borne pathogen can affect strain frequencies in both the host and vector, thereby affecting viral population dynamics. However little is known about inter-strain competition in one of the