Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Federico M. Giorgi"'
Autor:
Caterina Garone, Francesca De Giorgio, Nicola Balboni, Emanuela Aleo, Daniele Mercatelli, Federico M. Giorgi
Publikováno v:
Methods and Protocols
Volume 4
Issue 2
Methods and Protocols, Vol 4, Iss 28, p 28 (2021)
Volume 4
Issue 2
Methods and Protocols, Vol 4, Iss 28, p 28 (2021)
Cellular Indexing of Transcriptomes and Epitopes by Sequencing (CITE-seq) is a recently established multimodal single cell analysis technique combining the immunophenotyping capabilities of antibody labeling and cell sorting with the resolution of si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57024d222175a963fe2ef961e496324f
http://hdl.handle.net/11585/829368
http://hdl.handle.net/11585/829368
Autor:
Barry Honig, Diana Murray, Alexander Lachmann, Peter K. Jackson, David R. Simpson, Andrea Califano, E. Alejandro Sweet-Cordero, Sunny J. Jones, Somnath Tagore, Brennan Chu, Evan O. Paull, Federico M. Giorgi, Joshua Broyde, Aaron T. Griffin
Publikováno v:
Nature biotechnology, vol 39, iss 2
Nat Biotechnol
Nat Biotechnol
Tumor-specific elucidation of physical and functional oncoprotein interactions could improve tumorigenic mechanism characterization and therapeutic response prediction. Current interaction models and pathways, however, lack context specificity and ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d750cb705059dd4f64232fd4130928bd
http://hdl.handle.net/11585/785854
http://hdl.handle.net/11585/785854
Publikováno v:
Briefings in Bioinformatics
The current outbreak of COVID-19 has generated an unprecedented scientific response worldwide, with the generation of vast amounts of publicly available epidemiological, biological and clinical data. Bioinformatics scientists have quickly produced on
Autor:
Daniele Mercatelli, Federico M. Giorgi
Publikováno v:
Frontiers in Microbiology
Frontiers in Microbiology, Vol 11 (2020)
Frontiers in Microbiology, Vol 11 (2020)
The novel respiratory disease COVID-19 has reached the status of worldwide pandemic and large efforts are currently being undertaken in molecularly characterizing the virus causing it, SARS-CoV-2. The genomic variability of SARS-CoV-2 specimens scatt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f83cefe826718ecc0b4ffef83e391a9
Publikováno v:
Journal of Clinical Medicine
Journal of Clinical Medicine, Vol 9, Iss 982, p 982 (2020)
Journal of Clinical Medicine, 9(4):982
Volume 9
Issue 4
Journal of Clinical Medicine, Vol 9, Iss 982, p 982 (2020)
Journal of Clinical Medicine, 9(4):982
Volume 9
Issue 4
the recent epidemic outbreak of a novel human coronavirus called SARS-CoV-2 and causing the respiratory tract disease COVID-19 has reached worldwide resonance and a global effort is being undertaken to characterize the molecular features and evolutio
Publikováno v:
Bioinformatics (Oxford, England). 36(12)
MotivationGene Network Inference and Master Regulator Analysis (MRA) have been widely adopted to define specific transcriptional perturbations from gene expression signatures. Several tools exist to perform such analyses, but most require a computer
Autor:
Bruce A.J. Ponder, Tamar Paz-Elizur, Ronen Fluss, Martin O'Reilly, Robert C. Rintoul, Federico M. Giorgi, Laurence S. Freedman, Hyunjin Kim, Zvi Livneh, Yael Leitner-Dagan, Barak Markus, Yentl Evgy, Kerstin B. Meyer
Publikováno v:
JNCI Cancer Spectrum
Background Improving lung cancer risk assessment is required because current early-detection screening criteria miss most cases. We therefore examined the utility for lung cancer risk assessment of a DNA Repair score obtained from OGG1, MPG, and APE1
Autor:
Florian Markowetz, Amy E Cullen, Sankari Nagarajan, Andrew N Holding, Federico M. Giorgi, Amanda Donnelly, Luke A. Selth
Publikováno v:
Holding, A N, Giorgi, F M, Donnelly, A, Cullen, A E, Nagarajan, S, Selth, L A & Markowetz, F 2019, ' VULCAN integrates ChIP-seq with patient-derived co-expression networks to identify GRHL2 as a key co-regulator of ERa at enhancers in breast cancer ', Genome biology, vol. 20, no. 1 . https://doi.org/10.1186/s13059-019-1698-z
Genome Biology, Vol 20, Iss 1, Pp 1-16 (2019)
Genome Biology, Vol 20, Iss 1, Pp 1-16 (2019)
BackgroundVirtUaL ChIP-seq Analysis through Networks (VULCAN) infers regulatory interactions of transcription factors by overlaying networks generated from publicly available tumor expression data onto ChIP-seq data. We apply our method to dissect th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::617bf496f488e44f30a5814f52a23286
Autor:
Alessandro Vasciaveo, Andrea Califano, Brennan Chu, Somnath Tagore, Sunny J. Jones, Cory Abate-Shen, Federico M. Giorgi, Evan O. Paull, Siyuan Zheng, Prem S. Subramaniam, Mariano J. Alvarez, Eugene F Douglass, Alvaro Aytes, Roel G.W. Verhaak
Publikováno v:
Cell
Despite considerable efforts, the mechanisms linking genomic alterations to the transcriptional identity of cancer cells remain elusive. Integrative genomic analysis, using a network-based approach, identified 407 master regulator (MR) proteins respo
Autor:
Andrea Califano, Federico M. Giorgi, E. Alejandro Sweet-Cordero, Barry Honig, Diana Murray, Peter K. Jackson, David R. Simpson, Alexander Lachmann, Joshua Broyde
The largely incomplete and tissue-independent nature of cancer pathways represents a key limitation to the ability to elucidate mechanistic determinants of cancer phenotypes and to predict adaptive response to targeted therapy. To address these chall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe04232ca62dc4f17af0362a313792cc
https://doi.org/10.1101/289538
https://doi.org/10.1101/289538