Zobrazeno 1 - 10
of 57 272
pro vyhledávání: '"Biophysics"'
Publikováno v:
J Biomol Struct Dyn
Modulation of proteasome function by pharmacological interventions and molecular biology tools is an active area of research in cancer biology and neurodegenerative diseases. Curcumin (diferuloylmethane) is a naturally occurring polyphenol that affec
Autor:
Ali Sadeghi-Naini, Alborz Gorjizadeh, Hyunjung Christina Kim, Azza Al-Mahrouki, Raffi Karshafian, Gregory J. Czarnota
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 7, p e102343 (2014)
PLoS ONE, Vol 9, Iss 7, p e102343 (2014)
The aim of this study was to assess the efficacy of quantitative ultrasound imaging in characterizing cancer cell death caused by enhanced radiation treatments. This investigation focused on developing this ultrasound modality as an imaging-based non
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65b1faeddc6d9cd9391ea31d52c968e9
https://doi.org/10.32920/14668827.v1
https://doi.org/10.32920/14668827.v1
Autor:
David Benoist, David Baddeley, Nicolas P. Smith, Richard D. Walton, Gregory B. Sands, Bruce H. Smaill, Olivier Bernus, Igor R. Efimov, Mark L. Trew, Jesse L. Ashton
Publikováno v:
Progress in Biophysics and Molecular Biology. 168:18-32
Recent developments in clearing and microscopy enable 3D imaging with cellular resolution up to the whole organ level. These methods have been used extensively in neurobiology, but their uptake in other fields has been much more limited. Application
Publikováno v:
Frontiers in Pharmacology. 14
The voltage-gated sodium (Nav) channel subtype Nav1.7 plays a critical role in pain signaling, making it an important drug target. A number of peptide toxins from cone snails (conotoxins) bind to the extracellular vestibule of the Nav channel pore an
Publikováno v:
Nano Letters, 21(22). American Chemical Society
Nano Letters
Nano Letters
Super-resolution microscopy via PAINT has been widely adopted in life sciences to interrogate the nanoscale architecture of many cellular structures. However, obtaining quantitative information in fixed cellular samples remains challenging because co
Autor:
Gunnar Jeschke, Christoph Gmeiner, Daniel Klose, Maxim Yulikov, Andrea Holla, Daniel Nettels, Irina Ritsch, Frédéric H.-T. Allain, Benjamin Schuler, Nadja Bross
Publikováno v:
Biophys J
Biophysical Journal, 120 (21)
Biophysical Journal, 120 (21)
Förster resonance energy transfer (FRET) and electron paramagnetic resonance (EPR) spectroscopy are complementary techniques for quantifying distances in the nanometer range. Both approaches are commonly employed for probing the conformations and co
Autor:
Crescent L. Combe, Sonia Gasparini
Publikováno v:
Prog Biophys Mol Biol
Hyperpolarization-activated cyclic nucleotide gated (HCN) channels and the current they carry, Ih, are widely and diversely distributed in the central nervous system (CNS). The distribution of the four subunits of HCN channels is variable within the
Autor:
Michael Levin
Publikováno v:
Progress in Biophysics and Molecular Biology. 165:102-113
One lens with which to understand the complex phenomenon of cancer is that of developmental biology. Cancer is the inevitable consequence of a breakdown of the communication that enables individual cells to join into computational networks that work
Publikováno v:
Nature Methods
Nature methods
Nature methods
The quantification of membrane-associated biomolecular interactions is crucial to our understanding of various cellular processes. State-of-the-art single-molecule approaches rely largely on the addition of fluorescent labels, which complicates the q
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Communications Biology
Communications Biology
The HIV-1 envelope glycoprotein (Env) mediates viral entry into the host cell. Although the highly dynamic nature of Env intramolecular conformations has been shown with single molecule spectroscopy in vitro, the bona fide Env intra- and intermolecul