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pro vyhledávání: '"Mandy L. Ford"'
Autor:
Anna B. Morris, Mandy L. Ford
Publikováno v:
Curr Opin Organ Transplant
Purpose of review Studies on adaptive cells have largely focused on features that are specific to adaptive immunity. However, adaptive cells utilize innate cell features to modulate their responses, and this area of T and B-cell biology is understudi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04bb1a89968e6e732cfd7a4e933c3d07
https://europepmc.org/articles/PMC7175961/
https://europepmc.org/articles/PMC7175961/
Autor:
Danya Liu, Maylene E. Wagener, G. Ding, Idelberto R. Badell, G. M. La Muraglia, Mandy L. Ford
Publikováno v:
American Journal of Transplantation. 18:89-101
Donor-specific antibodies (DSA) are a barrier to improved long-term outcomes following kidney transplantation. Costimulation blockade with CTLA-4-Ig has shown promise as a potential therapeutic strategy to control DSA. T follicular helper (Tfh) cells
Publikováno v:
Am J Transplant
Donor-specific antibodies (DSA) contribute to renal allograft loss. However, biomarkers to guide clinical management of DSA post-transplant or detect humoral alloimmune responses before alloantibodies develop are not available. Circulating T follicul
Autor:
Mandy L. Ford
Publikováno v:
Immunity. 44:1020-1033
The ultimate outcome of alloreactivity versus tolerance following transplantation is potently influenced by the constellation of cosignaling molecules expressed by immune cells during priming with alloantigen, and the net sum of costimulatory and coi
Publikováno v:
JCI insight. 3(1)
Memory T cells pose a significant problem to successful therapeutic control of unwanted immune responses during autoimmunity and transplantation, as they are differentially controlled by cosignaling receptors such as CD28 and CTLA-4. Treatment with a
Autor:
I. Raul Badell, Mandy L. Ford
Publikováno v:
Current opinion in organ transplantation. 21(1)
PURPOSE OF REVIEW T follicular helper (Tfh) cells are an increasingly relevant CD4 T cell subset responsible for the provision of help to B cells for the generation of an effective humoral immune response. Here we review recent studies that have prov
Autor:
Joshua A. Albrecht, David V. Mathews, Andrew B. Adams, Steven C. Kim, Mandy L. Ford, Kenneth A. Newell, Jun Wang, Alton B. Farris, Aron E. Lukacher, Ying Dong, Cynthia P. Breeden
Publikováno v:
Transplantation Direct
Background The interplay between viral infection and alloimmunity is known to influence the fate of transplanted organs. Clarifying how local virus-associated inflammation/injury and antiviral immunity can alter host alloimmune responses in transplan