Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Paul K. Audhya"'
Autor:
C. Kors van der Ent, Renske van der Meer, Sylvia F. Boj, Robert G.J. Vries, Harry G.M. Heijerman, Peter van Mourik, Paul K. Audhya, Jamie R Doyle, Jeffrey M. Beekman, Zheng Jason Yuan, N. Kinnman, Gitte Berkers
Publikováno v:
Journal of Cystic Fibrosis. 20:761-767
Background Previous in vitro organoid data showed A455E–CFTR, a rare CFTR mutation with 4.1% prevalence in the Netherlands, responds to lumacaftor/ivacaftor (LUM/IVA). We explored LUM/IVA's clinical efficacy in people with CF and ≥1 A455E–CFTR
Autor:
Neil Ahluwalia, Bote G. Bruinsma, Carsten Schwarz, Margaret E. Duncan, Rainald Fischer, Ralph Epaud, Paul K. Audhya, X You, Ross C. Klingsberg, Steven M. Rowe, Thomas J. Ferro, Sivagurunathan Sutharsan
Publikováno v:
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society. 20(2)
Background: Increased rates of respiratory adverse events have been observed in people ≥12 years of age with cystic fibrosis homozygous for the Phe508del-CFTR mutation treated with lumacaftor/ivacaftor, particularly in those with percent predicted