Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jan B. Koenderink"'
Autor:
Jan B. Koenderink, Frans G. M. Russel, Ron H.J. Mathijssen, Marcel M. Verbeek, Laurens F. M. Verscheijden, Saskia N. de Wildt, Carlijn H. C. Litjens
Publikováno v:
Plos Computational Biology, 17
Plos Computational Biology, 17, 3
PLoS Computational Biology, 17(3):e1008786. Public Library of Science
PLoS Computational Biology
PLoS Computational Biology, Vol 17, Iss 3, p e1008786 (2021)
Plos Computational Biology, 17, 3
PLoS Computational Biology, 17(3):e1008786. Public Library of Science
PLoS Computational Biology
PLoS Computational Biology, Vol 17, Iss 3, p e1008786 (2021)
Morphine is a widely used opioid analgesic, which shows large differences in clinical response in children, even when aiming for equivalent plasma drug concentrations. Age-dependent brain disposition of morphine could contribute to this variability,
Autor:
Jeroen J. M. W. van den Heuvel, Galvin Vredenburg, Frans G. M. Russel, Ab Bilos, Nico P. E. Vermeulen, Jan B. Koenderink
Publikováno v:
Koenderink, J B, van den Heuvel, J J M W, Bilos, A, Vredenburg, G, Vermeulen, N P E & Russel, F G M 2020, ' Human multidrug resistance protein 4 (MRP4) is a cellular efflux transporter for paracetamol glutathione and cysteine conjugates ', Archives of Toxicology, vol. 94, no. 9, pp. 3027-3032 . https://doi.org/10.1007/s00204-020-02793-4
Archives of Toxicology, 94, 9, pp. 3027-3032
Archives of Toxicology, 94(9), 3027-3032. Springer Verlag
Archives of Toxicology, 94, 3027-3032
Archives of Toxicology
Archives of Toxicology, 94, 9, pp. 3027-3032
Archives of Toxicology, 94(9), 3027-3032. Springer Verlag
Archives of Toxicology, 94, 3027-3032
Archives of Toxicology
Paracetamol (acetaminophen, APAP) overdose is a leading cause of acute drug-induced liver failure. APAP hepatotoxicity is mediated by the reactive metabolite N-acetyl-p-benzoquinone imine (NAPQI). NAPQI is inactivated by conjugation with glutathione
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76a43eb8d3c857f5efff355c65e2a5f3
https://research.vu.nl/en/publications/3a712037-5c16-4ed9-a07a-645cade77b67
https://research.vu.nl/en/publications/3a712037-5c16-4ed9-a07a-645cade77b67
Publikováno v:
Basic & Clinical Pharmacology & Toxicology, 125, 6, pp. 490-498
Basic & Clinical Pharmacology & Toxicology, 125, 490-498
Basic & Clinical Pharmacology & Toxicology, 125, 490-498
Contains fulltext : 215788.pdf (Publisher’s version ) (Closed access) Nicotine is the addiction causing alkaloid in tobacco, and it is used in smoking cessation therapies. Although the metabolic pathways of nicotine are well known and mainly occur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5e2c59afd9449ffbb36c417688db9b8
https://doi.org/10.1111/bcpt.13281
https://doi.org/10.1111/bcpt.13281
Autor:
Rovina Ruslami, Reinout van Crevel, David M. Burger, Nanny N M Soetedjo, Eleonora W. J. van Ewijk-Beneken Kolmer, Resvi Livia, Rob E. Aarnoutse, Bachti Alisjahbana, Prayudi Santoso, Vycke Yunivita, Lindsey H.M. te Brake, Jan B. Koenderink
Publikováno v:
Clinical Pharmacology and Therapeutics, 105, 730-737
Clinical Pharmacology and Therapeutics, 105, 3, pp. 730-737
Clinical Pharmacology and Therapeutics
Clinical Pharmacology and Therapeutics, 105, 3, pp. 730-737
Clinical Pharmacology and Therapeutics
The pharmacokinetic (PK) and clinical implications of combining metformin with rifampicin are relevant to increasing numbers of patients with diabetic tuberculosis (TB) across the world and are yet unclear. We assessed the impact of rifampicin on met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c34545c9b21a6344f27b6a69dc264faa
http://hdl.handle.net/2066/202131
http://hdl.handle.net/2066/202131
Autor:
Jan B. Koenderink, Reinout van Crevel, Albert Bilos, Rob E. Aarnoutse, Lindsey H.M. te Brake, Aaron Ohene Buaben, Jeroen J. M. W. van den Heuvel, Frans G. M. Russel
Publikováno v:
Antimicrobial Agents and Chemotherapy, 60, 7105-7114
Antimicrobial Agents and Chemotherapy, 60, 12, pp. 7105-7114
Antimicrobial Agents and Chemotherapy, 60, 12, pp. 7105-7114
It is largely unknown if simultaneous administration of tuberculosis (TB) drugs and metformin leads to drug-drug interactions (DDIs). Disposition of metformin is determined by organic cation transporters (OCTs) and multidrug and toxin extrusion prote
Autor:
Albert Bilos, Elnaz Gozalpour, Jan B. Koenderink, Frans G. M. Russel, Martijn J. Wilmer, Rosalinde Masereeuw
Publikováno v:
Toxicology in Vitro, 32, 138-45
Toxicology in Vitro, 32, pp. 138-45
Toxicology in Vitro, 32, pp. 138-45
Contains fulltext : 170844.pdf (Publisher’s version ) (Closed access) Digitalis-like compounds (DLCs), the ancient medication of heart failure and Na,K-ATPase inhibitors, are characterized by their toxicity. Drug-drug interactions (DDIs) at absorpt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d86bd28196494a3c3db991976533111
http://hdl.handle.net/2066/170844
http://hdl.handle.net/2066/170844
Autor:
Jeroen J. M. W. van den Heuvel, David M. Burger, Roger J. M. Brüggemann, Rob E. Aarnoutse, Vincent J. Lempers, Frans G. M. Russel, Jan B. Koenderink
Publikováno v:
Antimicrobial Agents and Chemotherapy, 60, 3372-9
Antimicrobial Agents and Chemotherapy, 60, 6, pp. 3372-9
Antimicrobial Agents and Chemotherapy, 60, 6, pp. 3372-9
Inhibition of ABC transporters is a common mechanism underlying drug-drug interactions (DDIs). We determined the inhibitory potential of antifungal drugs currently used for invasive fungal infections on ABC transporters P-glycoprotein (P-gp), MRP1 to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5b4375520f81fc3b81e1c7a48fcf51f
https://doi.org/10.1128/AAC.02931-15
https://doi.org/10.1128/AAC.02931-15