Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Yunshan Wang"'
Autor:
Yunshan Wang, Guangwei Wei, Jian-Hua Mao, Maoxiao Feng, Pengju Zhang, Huaizhi Wang, Zhongxi Zhao, Lei Bi
Publikováno v:
Oncogene
Oncogene, vol 40, iss 11
Oncogene, vol 40, iss 11
Genomic instability induced by DNA damage and improper DNA damage repair is one of the main causes of malignant transformation and tumorigenesis. DNA double strand breaks (DSBs) are the most detrimental form of DNA damage, and nonhomologous end-joini
Autor:
Lei Bi, Fuqiong Zhou, Peng Meng, Bo Tang, Yidan Ren, Yunshan Wang, Yu-Cui Jiang, Weiping Chen, Qin Wang, Chuanxin Wang, Maoxiao Feng, Yuli Wang, Feiyan Chen, Qinlian Jiao, Lutao Du
Publikováno v:
Cancer Research. 81:2015-2028
Hepatocellular carcinoma (HCC) contains a subset of cancer stem cells (CSC) that cause tumor recurrence, metastasis, and chemical resistance. Histone deacetylase 11 (HDAC11) mediates diverse immune functions and metabolism, yet little is known about
Autor:
Hubo Shi, Chengke Zhang, Chengjun Zhou, Yu Liu, Yuliang Li, Chuanliang Peng, Yingtao Hao, Yunshan Wang, Xiaogang Zhao, Jie Zhou, Li Peichao, Weiquan Zhang, Ning Jiang, Qifeng Sun, Wenhao Zhang
Publikováno v:
Thoracic Cancer. 12:181-193
BACKGROUND To distinguish early-stage lung cancer from benign disease in pulmonary nodules, especially lesions with ground-glass opacity (GGO), we assessed gene mutations of ctDNA in peripheral blood using targeted next-generation sequencing (NGS). M
Autor:
Helen Binang, Mi Qi, Juan Li, Ning Li, Qing Wang, Peilong Li, Yingjie Chen, Yan Xie, Chuanxin Wang, Yanlei Wang, Haiting Mao, Yunshan Wang, Lili Wang, Lutao Du
Publikováno v:
Journal of Cellular and Molecular Medicine
Long non‐coding RNAs (lncRNAs) have come out as critical molecular regulators of human tumorigenesis. In this study, we sought to identify and functionally characterize lncRNAs as potential mediators of colorectal cancer progression. We screened an
Autor:
Hai-Yan Ding, Guo-Qing Zhang, Ping Shi, Chenjing Wang, Yanping Liu, Yunshan Wang, Xin Li, Yu Cao, Ting Li, Ping-Ping Lin
Publikováno v:
Cell Death and Disease, Vol 11, Iss 5, Pp 1-14 (2020)
Cell Death & Disease
Cell Death & Disease
Holliday junction recognition protein (HJURP) refers to a histone H3 chaperone that has been implicated in different kinds of malignancies. Yet, its character in pancreatic cancer remains unclear. The expression of HJURP was assessed in PDAC tissues
Autor:
Yunshan Wang, Yuli Wang, Yidan Ren, Fang Wang, Peilong Li, Peng Meng, Chuanxin Wang, Juan Li, Qinlian Jiao, Xiaoyan Liu, Lutao Du
Publikováno v:
Theranostics
Rationale: It has been proposed that cancer stem/progenitor cells (or tumor-initiating cells, TICs) account for breast cancer initiation and progression. Sirtuins are nicotinamide adenine dinucleotide (NAD+)-dependent class-III histone deacetylases a
Autor:
Xiang-Dong Liu, Mingjie Yuan, Shuyi Han, Jun Wang, Jing Wang, Yihui Xu, Yanfei Jia, Xiaoli Ma, Min Wang, Yan Qi, Yunshan Wang
Publikováno v:
Cancer Cell International, Vol 21, Iss 1, Pp 1-11 (2021)
Cancer Cell International
Cancer Cell International
Background Gastric cancer (GC) remains an important cancer worldwide. Further understanding of the molecular mechanisms of gastric carcinogenesis will enhance the diagnosis and treatment of GC. Methods The expression of DLEU2 and ETS2 was analyzed in
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Frontiers in Cell and Developmental Biology
Frontiers in Cell and Developmental Biology
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers with minimally effective treatments, highlighting the importance of developing novel biomarkers and therapeutic targets. Here, we disclosed the mechanisms that leukocyte cell-d
Autor:
Yunshan Wang, Ji-Eun Kim, Roshane Francis, Shaheed W Hakim, Jung-Eun Kim, Housheng Hansen He, Jieun Seo, Tae-Hee Kim, Haiyang Guo, Adrian Kwan Ho Loe, Lutao Du
Publikováno v:
The Journal of Experimental Medicine
Loe et al. demonstrate dosage-dependent roles of Arid1a, whereby the loss of its single copy promotes tumor progression, but tumor cells lacking both copies exhibit a survival disadvantage. This finding leads to a novel combined targeting approach fo
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-13 (2019)
Journal of Experimental & Clinical Cancer Research : CR
Journal of Experimental & Clinical Cancer Research : CR
Background Ubiquitin E3 ligase CUL4A plays important oncogenic roles in the development of cancers. DTL, one of the CUL4-DDB1 associated factors (DCAFs), may involve in the process of cancer development. Programmed cell death 4 (PDCD4) is a tumor sup