Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Thomas Farge"'
Autor:
Lara Gales, Camille Montersino, Marc Conti, Pierre Bories, Courtney D. DiNardo, Brandon Nicolay, Fabien Jourdan, Nicolas Broin, Mohsen Hosseini, Guillaume Cognet, Yves Gibon, Marie Sabatier, Tony Kaoma, Marina Konopleva, Lucille Stuani, Mathilde Gotanègre, Christian Recher, Laurent Fernando, Vera Pancaldi, Nathalie Poupin, Estelle Saland, Jean-Emmanuel Sarry, Joseph R. Marszalek, Andrei Turtoi, Thomas Farge, Feng Wang, Yves Collette, Laurent Le Cam, Madi Y. Cissé, Cédric Cassan, Alexis Hucteau, Claudie Bosc, Natalia Baran, Sebastien Ronseaux, Aliki Zavoriti, François Fenaille, Florence Castelli, Laetitia K. Linares, Evgenia Turtoi, Emeline Chu-Van, Martin Carroll, Pierre-Luc Mouchel, Mary A. Selak, Guillaume Cazals, Emeline Boet, Rémy Castellano, Floriant Bellvert, Norbert Vey, Clément Larrue, Koichi Takahashi, Ambrine Sahal, Sylvain Loric, Jean-Charles Portais
Publikováno v:
Journal of Experimental Medicine
Journal of Experimental Medicine, 2021, 218 (5), pp.e20200924. ⟨10.1084/jem.20200924⟩
Journal of Experimental Medicine, Rockefeller University Press, 2021, 218 (5), ⟨10.1084/jem.20200924⟩
The Journal of Experimental Medicine
Journal of Experimental Medicine, 2021, 218 (5), pp.e20200924. ⟨10.1084/jem.20200924⟩
Journal of Experimental Medicine, Rockefeller University Press, 2021, 218 (5), ⟨10.1084/jem.20200924⟩
The Journal of Experimental Medicine
Stuani et al. demonstrate that IDH mutant AML cells display an enhanced mitochondrial phenotype, which is not reversed by IDH mutant inhibitors. This study provides a scientific rationale for combinatory mitochondrial-targeted therapies to treat IDH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dfb2b30f8b948c067d643d1119fbb0e
https://amu.hal.science/hal-03563454/file/jStuani_em_20200924.pdf
https://amu.hal.science/hal-03563454/file/jStuani_em_20200924.pdf
Autor:
Thomas Farge, Marie-Virginie Larcher, Françoise Huguet, Estelle Saland, Suzanne Tavitian, Emilie Bérard, Audrey Sarry, Mauricette Michallet, François Vergez, Sarah Bertoli, Claudie Bosc, Etienne Paubelle, Jean-Emmanuel Sarry, Eric Delabesse, Xavier Thomas, Christian Recher, Clément Larrue
Publikováno v:
European Journal of Haematology. 102:131-142
Objectives We previously reported the prognostic value of serum ferritin in younger patients with intermediate-risk acute myeloid leukemia (AML). The aims of this study were to confirm this finding in a larger cohort regardless of age and prognostic
Autor:
Margherita Ghisi, Jerome Tamburini, Marie Sabatier, Massimiliano Bardotti, Francisco Azuaje, Jean-Charles Portais, Christian Récher, Carine Joffre, Lucille Stuani, Pierre-Luc Mouchel, Camille Laurent, Marie-Laure Nicolau-Travers, Fetta Mazed, Claudie Bosc, Nathalie Nicot, Nesrine Aroua, Mathilde Gotanègre, Jean-Emmanuel Sarry, Estelle Saland, Clément Larrue, Floriant Bellvert, Fabienne De Toni, Latifa Jarrou, Mohsen Hosseini, Charlotte Syrykh, Ryan Gwilliam, François Vergez, Tony Kaoma, Sarah Gandarillas, Muriel Picard, Thomas Farge, Emeline Boet, Nathalie Bonnefoy
Publikováno v:
Cancer Discovery
Cancer Discovery, 2020, 10 (10), pp.1544-1565. ⟨10.1158/2159-8290.CD-19-1008⟩
Cancer Discovery, American Association for Cancer Research, 2020, 10 (10), pp.1544-1565. ⟨10.1158/2159-8290.CD-19-1008⟩
Cancer Discovery, 2020, 10 (10), pp.1544-1565. ⟨10.1158/2159-8290.CD-19-1008⟩
Cancer Discovery, American Association for Cancer Research, 2020, 10 (10), pp.1544-1565. ⟨10.1158/2159-8290.CD-19-1008⟩
Relapses driven by chemoresistant leukemic cell populations are the main cause of mortality for patients with acute myeloid leukemia (AML). Here, we show that the ectonucleotidase CD39 (ENTPD1) is upregulated in cytarabine-resistant leukemic cells fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12d1d987207bbabb0832871f8ebdd298
https://hal.inrae.fr/hal-02983257
https://hal.inrae.fr/hal-02983257
Autor:
Floriant Bellvert, Camille Montersino, Pierre-Luc Mouchel, Brandon Nicolay, Guillaume Cazals, Laurent Fernando, Nicolas Broin, Jean-Charles Portais, Joe Marszalek, Clément Larrue, Norbert Vey, Sebastien Ronseaux, Thomas Farge, Jean-Emmanuel Sarry, Andrei Turtoi, Aliki Zavoriti, Tony Kaoma, Courtney D. DiNardo, Emeline Chu-Van, Claudie Bosc, Guillaume Cognet, Rémy Castellano, Héléna Boutzen, Cédric Cassan, Claire Calmettes, Florence Castelli, Marie Sabatier, Arnaud Pigneux, Evgenia Turtoi, Yves Collette, Martin Carroll, Yves Gibon, Emeline Boet, Laetitia K. Linares, Mathilde Gotanègre, Francois Fenaille, Laurent Le Cam, Lara Gales, Marc Conti, Nathalie Poupin, Mary A. Selak, Lucille Stuani, Andrew Futreal, Christian Recher, Marina Konopleva, Feng Wang, Estelle Saland, Mohsen Hosseini, Audrey Bidet, Kiyomi Morita, Natalia Baran, Koichi Takahashi, Sylvain Loric, Pierre Bories, Fabien Jourdan
Isocitrate dehydrogenases (IDH) are involved in redox control and central metabolism. Mutations in IDH induce epigenetic and transcriptional reprogramming, differentiation bias, BCL-2 dependence and susceptibility to mitochondrial inhibitors in cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55157cd88bc325916e6636c39f8f7b18
https://hal.archives-ouvertes.fr/hal-02935177
https://hal.archives-ouvertes.fr/hal-02935177
Autor:
Claudie Bosc, Jean-Emmanuel Sarry, Marc Piechaczyk, Thomas Farge, Sonia Zaghdoudi, Mohsen Hosseini, Hamid Reza Rezvani, Véronique Guyonnet-Duperat, Clément Larrue, Mathilde Gotanègre, Nesrine Aroua, Pierre Luc Mouchel, Latifa Jarrou, Marie Sabatier, Christian Recher, Guillaume Bossis, Estelle Saland
Publikováno v:
Cancer Research
Cancer Research, American Association for Cancer Research, 2019, 79 (20), pp.5191-5203. ⟨10.1158/0008-5472.CAN-19-0515⟩
Cancer Research, American Association for Cancer Research, 2019, 79 (20), pp.5191-5203. ⟨10.1158/0008-5472.CAN-19-0515⟩
Chemotherapies alter cellular redox balance and reactive oxygen species (ROS) content. Recent studies have reported that chemoresistant cells have an increased oxidative state in hematologic malignancies. In this study, we demonstrated that chemoresi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc41bc9f60c1650a8b74e7e7404e62da
https://hal.umontpellier.fr/hal-02394533
https://hal.umontpellier.fr/hal-02394533
Autor:
Christian Récher, Marc Poirot, Philippe de Medina, Rémy Betous, Jean-Emmanuel Sarry, Sandrine Silvente-Poirot, Thomas Farge, Estelle Saland, Pierre-Luc Mouchel, Jean-Sébastien Hoffmann, Nizar Serhan
Publikováno v:
Cancers
Volume 12
Issue 10
Cancers, 2020, 12 (10), pp.2933. ⟨10.3390/cancers12102933⟩
Cancers, MDPI, 2020, 12 (10), pp.2933. ⟨10.3390/cancers12102933⟩
Cancers, Vol 12, Iss 2933, p 2933 (2020)
Volume 12
Issue 10
Cancers, 2020, 12 (10), pp.2933. ⟨10.3390/cancers12102933⟩
Cancers, MDPI, 2020, 12 (10), pp.2933. ⟨10.3390/cancers12102933⟩
Cancers, Vol 12, Iss 2933, p 2933 (2020)
Dendrogenin A (DDA), a mammalian cholesterol metabolite with tumor suppressor properties, has recently been shown to exhibit strong anti-leukemic activity in acute myeloid leukemia (AML) cells by triggering lethal autophagy. Here, we demonstrated tha
Autor:
François Vergez, Marine Fraisse, Nicolas Broin, Thomas Farge, Robin L. Perry, Jean-Emmanuel Sarry, Audrey Sarry, Suzanne Tavitian, Stéphanie Cassant-Sourdy, Mayumi Sugita, Laetitia K. Linares, Jason S. Iacovoni, Claudie Bosc, Olivier Duchamp, Gwenn Danet-Desnoyers, Fabienne De Toni, Sarah J. Scotland, Y Barreira, Pierre Hirsch, Emmanuel Griessinger, Estelle Saland, Camille Montersino, Rémy Castellano, Héléna Boutzen, Nizar Serhan, Laurent Vallar, Martin Carroll, Christian Recher, Moshen Hosseini, Yves Collette, Lara Gales, François Delhommeau, Marion David, Marie-Laure Nicolau-Travers, Jean-Charles Portais, Nesrine Aroua, Lucille Stuani, Clément Larrue, Tony Kaoma, Tony Lionel Palama, Mary A. Selak, Barbara Garmy-Susini, Virginie Féliu
Publikováno v:
Cancer Discovery
Cancer Discovery, American Association for Cancer Research, 2017, 7 (7), pp.716-735. ⟨10.1158/2159-8290.cd-16-0441⟩
Cancer Discovery, American Association for Cancer Research, 2017, 7 (7), pp.716-735. ⟨10.1158/2159-8290.CD-16-0441⟩
Cancer Discovery, 2017, 7 (7), pp.716-735. ⟨10.1158/2159-8290.cd-16-0441⟩
Cancer Discovery, American Association for Cancer Research, 2017, 7 (7), pp.716-735. ⟨10.1158/2159-8290.cd-16-0441⟩
Cancer Discovery, American Association for Cancer Research, 2017, 7 (7), pp.716-735. ⟨10.1158/2159-8290.CD-16-0441⟩
Cancer Discovery, 2017, 7 (7), pp.716-735. ⟨10.1158/2159-8290.cd-16-0441⟩
Chemotherapy-resistant human acute myeloid leukemia (AML) cells are thought to be enriched in quiescent immature leukemic stem cells (LSC). To validate this hypothesis in vivo, we developed a clinically relevant chemotherapeutic approach treating pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66c6cd90750845fe1c10175feb49744a
https://hal.archives-ouvertes.fr/hal-01608532
https://hal.archives-ouvertes.fr/hal-01608532