Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Katri Koli"'
Autor:
Eva Sutinen, Henrik Wolff, Jari Räsänen, Tapio Vehmas, Katri Koli, Eeva Kuosma, Sanna Laaksonen, Jarmo A. Salo, Kirsti Husgafvel-Pursiainen, Ilkka Ilonen, Marjukka Myllärniemi
Publikováno v:
Acta Oncologica. 58:38-44
Background: Malignant pleural mesothelioma (MPM) is a rare occupational cancer with a poor prognosis. Even with a multimodality treatment approach, the treatment outcomes remain unsatisfactory. The use of asbestos has been banned in most developed co
Autor:
Mira Tissari, Irene Ylivinkka, Katri Koli, Pernilla von Nandelstadh, Mikko Rönty, Miao Yin, Kaisa Lehti, Jenni A. Tamminen, Marko Hyytiäinen, Marjukka Myllärniemi
Publikováno v:
Oncotarget
// Miao Yin 1, 2 , Mira Tissari 1, 2 , Jenni Tamminen 1, 2 , Irene Ylivinkka 1 , Mikko Ronty 3 , Pernilla von Nandelstadh 4 , Kaisa Lehti 4, 5, 6 , Marko Hyytiainen 4 , Marjukka Myllarniemi 7 and Katri Koli 1, 2 1 Research Programs Unit, Translationa
Autor:
Eeva Rouvinen, Marjukka Myllärniemi, Katri Koli, Helena Lauri, Jari Räsänen, Eva Sutinen, Ilkka Ilonen, Karl B. Lemström, Juuso Paajanen, Olli Ritvos, Tommi Järvinen, Hely Ollila
Publikováno v:
Clinical lung cancer. 21(3)
Activin A has previously been associated with cancer cachexia and in vitro resistance to platinum-based chemotherapy. We studied circulating activin A concentrations as well as activin B and their antagonists' follistatin/follistatin-like 3 in presur
Autor:
Ville Vartiainen, Katri Koli, Veronika Rezov, Emmi I. Joensuu, Chang Li, Mikko Rönty, Miao Yin, Marjukka Myllärniemi
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Malignant mesothelioma is an aggressive cancer with poor prognosis. It is characterized by prominent extracellular matrix, mesenchymal tumor cell phenotypes and chemoresistance. In this study, the ability of pirfenidone to alter mesothelioma cell pro
Publikováno v:
Molecular Endocrinology. 29:1787-1791
Recently, several LH/human chorionic gonadotropin (hCG) receptor-independent activities for hCG have been described, including activation of the TGF-β receptor (TGFβR) by hyperglycosylated hCG and stimulation of trophoblast invasion. Because the hC
Publikováno v:
Journal of Cellular Biochemistry. 113:2234-2247
The inhalation of asbestos fibers is considered to be highly harmful, and lead to fibrotic and/or malignant disease. Epithelial-to-mesenchymal transition (EMT) is a common pathogenic mechanism in asbestos associated fibrotic (asbestosis) and malignan
Publikováno v:
Bone. 43:679-688
Mesenchymal stem cells (MSCs) possess the capability to differentiate into bone forming cells, osteoblasts, and thus represent a new therapeutic tool in regenerative medicine. Transforming growth factor (TGF)-beta is abundantly present in bone tissue
Publikováno v:
Experimental Cell Research. 314:2488-2500
Latent transforming growth factor (TGF)-β binding proteins are extracellular matrix (ECM) proteins involved in the regulation of TGF-β sequestration and activation. In this study, we have identified binding domains in LTBP-4, which mediate matrix t
Autor:
Vuokko L. Kinnula, Jorma Keski-Oja, Marjukka Myllärniemi, Katri Koli, Kaisa Salmenkivi, T. Aine, Kirsi Vuorinen, Hannu Kankaanranta, Ville Pulkkinen
Publikováno v:
The Journal of Pathology. 214:456-463
Idiopathic pulmonary fibrosis (IPF) (histopathology of usual interstitial pneumonia, UIP) and non-specific interstitial pneumonia (NSIP) are diseases characterized by loss of normal lung architecture and function. The differential diagnosis between I
Publikováno v:
Experimental Cell Research. 310:370-382
Latent TGF-beta binding proteins (LTBPs) mediate the targeting of latent TGF-beta complexes into ECM structures, which is important for TGF-beta activation and functions. LTBPs-1, -3 and -4 associate with and regulate the bioavailability of TGF-betas