Zobrazeno 1 - 10
of 73
pro vyhledávání: '"David C. Rice"'
Autor:
John V. Heymach, Barbara Mino, J. Jack Lee, Pedro Rocha, Cesar A. Moran, David C. Rice, Edwin R. Parra, Humam Kadara, Boris Sepesi, Lei Feng, Luisa M. Solis, Carmen Behrens, Ignacio I. Wistuba, Don L. Gibbons, Jianjun Zhang, Chad J. Creighton, Jaime Rodriguez-Canales
Publikováno v:
Clinical Lung Cancer. 22:e415-e424
Introduction Immune infiltration in lung adenocarcinomas (LUADs) has been associated with response to immune checkpoint inhibitors. Clinical features underlying differential responses of patients with LUADs to immunotherapy are not well understood. H
Autor:
Wayne L. Hofstetter, Ara A. Vaporciyan, Mara B. Antonoff, Ravi Rajaram, Nicolas Zhou, Boris Sepesi, David C. Rice, Andres Zorrilla-Vaca, Reza J. Mehran, Hope A. Feldman
Publikováno v:
Journal of Surgical Oncology. 123:1633-1639
BACKGROUND: For patients with bilateral pulmonary metastases, staged resections have historically been the preferred surgical intervention. During the spring of 2020, the COVID-19 pandemic made patient travel to the hospital challenging and necessita
Autor:
Cheuk Hong Leung, Wayne L. Hofstetter, John V. Heymach, Alexandre Reuben, Myrna C.B. Godoy, Ara A. Vaporciyan, Padmanee Sharma, Yasir Elamin, Neda Kalhor, Robert R. Jenq, Junya Fujimoto, Tina Cascone, Anne S. Tsao, William N. William, Charles Lu, Frank E. Mott, Nadim J. Ajami, Don L. Gibbons, Jack A. Roth, David C. Rice, Luisa M. Solis, Hai T. Tran, Brett W. Carter, Lauren Averett Byers, Andrew Futreal, Lorenzo Federico, Annikka Weissferdt, Garrett L. Walsh, Reza J. Mehran, Chantale Bernatchez, George R. Blumenschein, Jennifer A. Wargo, Heather Lin, Cara Haymaker, Xiuning Le, Jonathan M. Kurie, Mehmet Altan, James P. Allison, Stephen G. Swisher, Edwin R. Parra, Boris Sepesi, Hitoshi Dejima, Frank V. Fossella, Jianjun Zhang, Bonnie S. Glisson, Mara B. Antonoff, Abdul Wadud Khan, Apar Pataer, Alejandro Francisco-Cruz, Ignacio I. Wistuba, Humam Kadara, J. Jack Lee, Ferdinandos Skoulidis
Publikováno v:
Nat Med
Ipilimumab improves clinical outcomes when combined with nivolumab in metastatic non-small cell lung cancer (NSCLC), but its efficacy and impact on the immune microenvironment in operable NSCLC remain unclear. We report the results of the phase 2 ran
Autor:
Mara B. Antonoff, Wayne L. Hofstetter, Garrett L. Walsh, Boris Sepesi, Jack A. Roth, Ravi Rajaram, Ara A. Vaporciyan, David C. Rice, Stephen G. Swisher, Kyle G. Mitchell, Erin M. Corsini, Nicolas Zhou, Reza J. Mehran
Publikováno v:
Journal of Gastrointestinal Surgery. 25:2185-2191
Most patients undergoing esophagectomy will experience intermittent reflux of gastric and biliary content into the remnant esophagus postoperatively. The incidence of new or recurrent intestinal metaplasia following chemoradiation and surgery has not
Autor:
Pedro Rocha, Dzifa Y. Douse, Lixia Diao, Humam Kadara, Jianjun Zhang, Debora A. Ledesma, Jose Luis Solorzano, John V. Heymach, Ruth Salazar, Luisa M. Solis, Neda Kalhor, Barbara Mino, J. Jack Lee, Don L. Gibbons, Cesar A. Moran, David C. Rice, Carmen Behrens, Pamela Villalobos, Ara A. Vaporciyan, Jiexin Zhang, Hitoshi Dejima, Annikka Weissferdt, Kyle G. Mitchell, Tina Cascone, Edwin Parra-Cuentas, Boris Sepesi, Xiuning Le, Ignacio I. Wistuba
Publikováno v:
Cancer Immunology, Immunotherapy
Introduction CD73 is a membrane-bound enzyme crucial in adenosine generation. The adenosinergic pathway plays a critical role in immunosuppression and in anti-tumor effects of immune checkpoint inhibitors (ICI). Here, we interrogated CD73 expression
Autor:
John V. Heymach, David C. Rice, Neda Kalhor, William N. William, Frank V. Fossella, Don L. Gibbons, Annikka Weissferdt, Vincent K. Lam, Stephen G. Swisher, Ara A. Vaporciyan, Frank E. Mott, Heather Lin, Boris Sepesi, J. Jack Lee, Ignacio I. Wistuba, Edwin R. Parra, Reza J. Mehran, Carmen Behrens, Anne S. Tsao, Mei Jiang, Jianjun Zhang, Tina Cascone, Cesar A. Moran, Charles Lu, Myrna C.B. Godoy, George R. Simon, Mara B. Antonoff
Publikováno v:
Clinical Cancer Research. 26:3525-3536
Purpose: Nintedanib enhances the activity of chemotherapy in metastatic non–small cell lung cancer (NSCLC). In this phase I/II study, we assessed safety and efficacy of nintedanib plus neoadjuvant chemotherapy, using major pathologic response (MPR)
Autor:
Tina Cascone, Ting Xu, Quynh Nhu Nguyen, David C. Rice, Jack A. Roth, Saumil Gandhi, Wayne L. Hofstetter, Zhongxing Liao, Arlene M. Correa, Mara B. Antonoff, Anne S. Tsao, Ara A. Vaporciyan, Reza J. Mehran, Ravi Rajaram, Stephen G. Swisher, Boris Sepesi, Vassiliki A. Papadimitrakopoulou, Garrett L. Walsh
Publikováno v:
Clinical Lung Cancer. 21:e294-e301
Introduction The standard of care for stage IIIA (N2) non–small-cell lung cancer (NSCLC) includes concurrent definitive chemoradiation (dCRT) followed by durvalumab, thus challenging the role of surgery in resectable patients. We assessed locoregio
Autor:
Erin M. Corsini, David C. Rice, Ara A. Vaporciyan, Kyle G. Mitchell, Jack A. Roth, Mara B. Antonoff, Stephen G. Swisher, Wayne L. Hofstetter, Boris Sepesi, Garrett L. Walsh, Reza J. Mehran
Publikováno v:
Journal of Surgical Oncology. 122:515-522
Background and objectives It is unclear if a specific strategy for simultaneous treatment of primary thymic neoplasms and pleural metastases confers benefit for Masaoka stage IVA disease. We reviewed our experience with thymic neoplasms with concurre
Autor:
Eric L. Brown, Garrett L. Walsh, Reza J. Mehran, Luis G LeonNovelo, Jack A. Roth, Jitesh B. Shewale, Arlene M. Correa, Ara A. Vaporciyan, Wayne L. Hofstetter, Boris Sepesi, Erin M. Corsini, Mara B. Antonoff, Stephen G. Swisher, David C. Rice, Alan G. Nyitray
Publikováno v:
Journal of Surgical Oncology. 122:495-505
Background The improvement in the management of lung cancer have the potential to improve survival in patients undergoing resection for early-stage (stage I and II) non-small cell lung cancer (NSCLC), but few studies have evaluated time trends and id
Autor:
Jack A. Roth, David C. Rice, Garrett L. Walsh, Ara A. Vaporciyan, Ravi Rajaram, Rodabe N. Amaria, Cara Haymaker, Erin M. Corsini, Mara B. Antonoff, Reza J. Mehran, Stephen G. Swisher, Wayne L. Hofstetter, Amir A. Jazaeri, Nicolas Zhou, Boris Sepesi, Chantale Bernatchez, Marie-Andree Forget, Kyle G. Mitchell
Publikováno v:
Journal of surgical oncologyREFERENCES. 124(4)
Background and objectives Adoptive T-cell therapies (ACTs) using expansion of tumor-infiltrating lymphocyte (TIL) populations are of great interest for advanced malignancies, with promising response rates in trial settings. However, postoperative out