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Autor:
Anya Plutynski
Publikováno v:
Frontiers in Ecology and Evolution, Vol 9 (2021)
Recently Hausser and Alon (2019, 2020) have argued that trade-offs in the evolution of a tumor constrain optimal traits. They describe a set of archetypical gene expression profiles, and represent different cancer types and subtypes as falling within
Autor:
Anya Plutynski
Publikováno v:
Biology & Philosophy. 36
In 2015, Tomasetti and Vogelstein published a paper in Science containing the following provocative statement: “… only a third of the variation in cancer risk among tissues is attributable to environmental factors or inherited predispositions. Th
Publikováno v:
Biology & Philosophy. 31:39-57
One of the major developments in cancer research in recent years has been the construction of models that treat cancer as a cellular population subject to natural selection. We expand on this idea, drawing upon multilevel selection theory. Cancer is