Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Ajay P. Singh"'
Autor:
James E. Carter, Luciana Madeira da Silva, Harrison Ndetan, Fnu Sameeta, Kate L. Hertweck, Seema Singh, Sanjeev K. Srivastava, Santanu Dasgupta, Karan Pal Singh, Orlandric Miree, Rodney P. Rocconi, Mohammad Aslam Khan, Srijan Acharya, Ajay P. Singh
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Scientific Reports
Scientific Reports
Late diagnosis, unreliable prognostic assessment, and poorly-guided therapeutic planning result in dismal survival of ovarian cancer (OC) patients. Therefore, identifying novel functional biomarker(s) is highly desired for improved clinical managemen
Publikováno v:
J Cell Biochem
Pancreatic tumors are highly desmoplastic and poorly-vascularized, and therefore must develop adaptive mechanisms to sustain their survival under hypoxic condition. Extracellular vesicles (EV) play vital roles in pancreatic tumor pathobiology by faci
Autor:
Santanu Dasgupta, Ajay P. Singh, Seema Singh, Sachin Pai, Sirin Saranyutanon, Sachin Kumar Deshmukh
Publikováno v:
Cancers, Vol 12, Iss 2651, p 2651 (2020)
Cancers
Cancers
Simple Summary The molecular progression of prostate cancer is complex and elusive. Biological research relies heavily on in vitro and in vivo models that can be used to examine gene functions and responses to the external agents in laboratory and pr
Autor:
Donna Lynn Dyess, Teja Poosarla, Sarabjeet Kour Sudan, Nicolette Holliday, Sachin Kumar Deshmukh, Seema Singh, Ajay P. Singh
Publikováno v:
Biochim Biophys Acta Rev Cancer
Systemic and organ-confined inflammation has been associated with cancer development and progression. Resistin, initially described as an adipocyte-derived cytokine in mice, is mostly expressed by the macrophages in humans. It has potent pro-inflamma
Autor:
Ajay P. Singh, Anu Singh Maharjan, Cindy Nelson, Peter J. Hosein, Moh’d Khushman, Gwendolyn A. McMillin, Girijesh Kumar Patel
Publikováno v:
The Pharmacogenomics Journal
Introduction The prevalence of 2R/2R TYMS genotype is variable but estimated to be around 20–30% in Caucasians. The clinical relevance of TYMS 2R/2R genotype in predicting severe fluoropyrimidine-related adverse events (FrAE) is controversial. Here
Autor:
Haseeb Zubair, Sanjeev K. Srivastava, Seema Singh, Shashi Anand, Mohammad Aslam Khan, Ajay P. Singh
Publikováno v:
Semin Cancer Biol
The development of cancer is not just the growth and proliferation of a single transformed cell, but its surrounding environment also coevolves with it. Indeed, successful cancer progression depends on the ability of the tumor cells to develop a supp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fba00032914a8a7cccea8e7518d88f44
https://europepmc.org/articles/PMC7688484/
https://europepmc.org/articles/PMC7688484/
Publikováno v:
Cancers
Cancers, Vol 12, Iss 1, p 51 (2019)
Cancers, Vol 12, Iss 1, p 51 (2019)
Prostate cancer is the mostly commonly diagnosed non-cutaneous malignancy and the second leading cause of cancer-related death affecting men in the United States. Moreover, it disproportionately affects the men of African origin, who exhibit signific
Autor:
Ajay P. Singh, Shashi Anand, Sanjeev K. Srivastava, Haseeb Zubair, Seema Singh, Mohammad Aslam Khan
Publikováno v:
Cancer Lett
Altered cellular metabolism is a hallmark of cancer. Metabolic rewiring in cancer cells occurs due to the activation of oncogenes, inactivation of tumor suppressor genes, and/or other adaptive changes in cell signaling pathways. Furthermore, altered
Autor:
Rodney P. Rocconi, Aamir Ahmad, Orlandric Miree, Girijesh Kumar Patel, Seema Singh, Ajay P. Singh, Sanjeev K. Srivastava
Publikováno v:
Journal of Ovarian Research, Vol 10, Iss 1, Pp 1-9 (2017)
Journal of Ovarian Research
Journal of Ovarian Research
Ovarian cancer (OC) is the most lethal gynecological malignancy, which disproportionately affects African American (AA) women. Lack of awareness and socioeconomic factors are considered important players in OC racial health disparity, while at the sa
Autor:
Ajay P. Singh, James E. Carter, Rodney P. Rocconi, Mohammad Aslam Khan, Aamir Ahmad, Seema Singh, Shafquat Azim, Haseeb Zubair
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer. 1868:16-28
Despite efforts at various levels, racial health disparities still exist in cancer patients. These inequalities in incidence and/or clinical outcome can only be explained by a multitude of factors, with genetic basis being one of them. Several invest