Zobrazeno 1 - 2
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pro vyhledávání: '"Gelderblom, Hans"'
Autor:
Lunenburg, Carin A T C, Henricks, Linda M, Guchelaar, Henk-Jan, Swen, Jesse J, Deenen, Maarten J, Schellens, Jan H M, Gelderblom, Hans, Sub Clinical Pharmacology, Pharmacoepidemiology and Clinical Pharmacology
Publikováno v:
European Journal of Cancer, 54, 40-48
European Journal of Cancer, 54, 40. Elsevier Ltd
European Journal of Cancer, 54, 40. Elsevier Ltd
5-Fluorouracil (5-FU) and capecitabine (CAP) are among the most frequently prescribed anticancer drugs. They are inactivated in the liver by the enzyme dihydropyrimidine dehydrogenase (DPD). Up to 5% of the population is DPD deficient and these patie
Autor:
Lancia, Carlo, Anninga, Jakob, Spitoni, Cristian, Sydes, Matthew R., Whelan, Jeremy, Hogendoorn, Pancras C.W., Gelderblom, Hans, Fiocco, Marta, Sub Mathematical Modeling, Mathematical Modeling
Publikováno v:
BMJ Open, 9(5). BMJ Publishing Group Ltd
BMJ Open
BMJ Open, 9(5)
BMJ Open
BMJ Open, 9(5)
ObjectivesIn cancer studies, the target received dose intensity (tRDI) for any regimen, the intended dose and time for the regimen, is commonly taken as a proxy for achieved RDI (aRDI), the actual individual dose and time for the regimen. Evaluating