Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Robert Somerville"'
Autor:
Steven A. Rosenberg, Arvind Sabesan, John R. Wunderlich, David N. Danforth, Christopher A. Klebanoff, Stephanie L. Goff, Mary Ann Toomey, Liqiang Xi, Daniel Zlott, Robert Somerville, James Chih-Hsin Yang, Mark Raffeld, Donald E. White, Trinh Hoc Tran Pham, Smita S. Chandran, Richard M. Sherry, Abhishek K. Srivastava, Udai S. Kammula, Biman C. Paria
Publikováno v:
The Lancet Oncology. 18:792-802
Summary Background Uveal melanoma is a rare tumour with no established treatments once metastases develop. Although a variety of immune-based therapies have shown efficacy in metastatic cutaneous melanoma, their use in ocular variants has been disapp
Autor:
John R. Wunderlich, Robert Somerville, Udai S. Kammula, James Chih-Hsin Yang, Richard M. Sherry, Steven A. Rosenberg, Sarah R. Helman, Mei Li M. Kwong, Michelle M. Langhan, Christopher A. Klebanoff, Stacey L. Doran, Christian S. Hinrichs, Sanja Stevanović
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 25(5)
Purpose: Cellular therapy is an emerging cancer treatment modality, but its application to epithelial cancers has been limited. This clinical trial evaluated tumor-infiltrating lymphocyte (TIL) therapy for the treatment of patients with metastatic hu
Autor:
John R. Wunderlich, Daniel J. Stephens, Liqiang Xi, Biman C. Paria, Smita S. Chandran, Arvind Sabesan, Mark Raffeld, Parthav Jailwala, Manjula Kasoji, Robert Somerville, Chyi-Chia Richard Lee, Trinh Hoc Tran Pham, Luke D. Rothermel, Abhishek K. Srivastava, Udai S. Kammula
Publikováno v:
Clinical Cancer Research. 22:2237-2249
Purpose: Uveal melanoma is a rare melanoma variant with no effective therapies once metastases develop. Although durable cancer regression can be achieved in metastatic cutaneous melanoma with immunotherapies that augment naturally existing antitumor
Autor:
Norris Lam, Steven A. Rosenberg, John J. Rossi, James N. Kochenderfer, Adrian Bot, Robert Somerville, James Chih-Hsin Yang, Richard M. Sherry, Steven A. Feldman, Lori McIntyre, Tangying Lu
Publikováno v:
Molecular therapy : the journal of the American Society of Gene Therapy. 25(10)
T cells expressing anti-CD19 chimeric antigen receptors (CARs) can induce complete remissions (CRs) of diffuse large B cell lymphoma (DLBCL). The long-term durability of these remissions is unknown. We administered anti-CD19 CAR T cells preceded by c
Autor:
Kathleen E. Morton, Udai S. Kammula, David N. Danforth, Thomas E. Shelton, Sadia Ilyas, Richard M. Sherry, Mary Ann Toomey, Eden C. Payabyab, Donald E. White, Seth M. Steinberg, Nicholas P. Restifo, Christopher A. Klebanoff, Michael S. Hughes, Steven A. Rosenberg, Mark E. Dudley, Deborah Citrin, Lily Lu, Nicholas D. Klemen, Mei Li M. Kwong, Daniel Zlott, James Chih-Hsin Yang, Michelle M. Langhan, John R. Wunderlich, Robert Somerville, Stephanie L. Goff
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 34(20)
Purpose Adoptive cell transfer, the infusion of large numbers of activated autologous lymphocytes, can mediate objective tumor regression in a majority of patients with metastatic melanoma (52 of 93; 56%). Addition and intensification of total body i
Autor:
Steven A. Rosenberg, Victoria Shi, Tangying L. Lu, Roger Kurlander, R. E. Gress, Brenna G. Hansen, Dennis D. Hickstein, Jeremy J. Rose, Steven A. Feldman, Jennifer N. Brudno, David Halverson, Bazetta Blacklock-Schuver, Irina Maric, Jennifer S. Wilder, Daniel H. Fowler, Robert Somerville, Juan C. Gea-Banacloche, Frances T. Hakim, Steven Z. Pavletic, James N. Kochenderfer, Andre Goy, Alexander T. Iwamoto
Purpose Progressive malignancy is the leading cause of death after allogeneic hematopoietic stem-cell transplantation (alloHSCT). After alloHSCT, B-cell malignancies often are treated with unmanipulated donor lymphocyte infusions (DLIs) from the tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78731f1c73af0683f0b5eca4e5d2e804
https://europepmc.org/articles/PMC4872017/
https://europepmc.org/articles/PMC4872017/