Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Simona Simone"'
Autor:
Simona Simone, Anna Gallone, Giovanni Stallone, Claudia Cinefra, Francesca Conserva, Chiara Divella, Michele Rossini, Paola Pontrelli, Viviana Casagrande, Giuseppe Castellano, Francesco Pesce, Francesco Giorgino, Massimo Federici, Mariagrazia Barozzino, Rossella Menghini, Loreto Gesualdo, Alessandra Stasi
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 10
International Journal of Molecular Sciences, Vol 22, Iss 5194, p 5194 (2021)
Volume 22
Issue 10
International Journal of Molecular Sciences, Vol 22, Iss 5194, p 5194 (2021)
Diabetic nephropathy (DN) is the most frequent cause of end-stage renal disease. Tubulointerstitial accumulation of lysine 63 (K63)-ubiquitinated (Ub) proteins is involved in the progression of DN fibrosis and correlates with urinary miR-27b-3p downr
Autor:
Grazia Vocino, Giuseppe Grandaliano, Luigi Laviola, Paola Pontrelli, Annarita Oranger, Francesca Conserva, Giuseppe Castellano, Francesco Giorgino, Margherita Gigante, Mariagrazia Barozzino, Salvatore Di Paolo, Michele Rossini, Maria Teresa Rocchetti, Massimo Papale, Simona Simone, Loreto Gesualdo
Publikováno v:
The FASEB Journal. 31:308-319
The purpose of our study was to evaluate how hyperglycemia (HG) influences Lys63 protein ubiquitination and its involvement in tubular damage and fibrosis in diabetic nephropathy (DN). Gene and protein expression of UBE2v1, a ubiquitin-conjugating E2
Publikováno v:
Diabetes
OBJECTIVE—To investigate potential mechanisms of oxidative DNA damage in a rat model of type 1 diabetes and in murine proximal tubular epithelial cells and primary culture of rat proximal tubular epithelial cells. RESEARCH DESIGN AND METHODS—Phos