Zobrazeno 1 - 1
of 1
pro vyhledávání: '"Gelderblom, Hans"'
Autor:
Lunenburg, Carin A T C, Henricks, Linda M, Guchelaar, Henk-Jan, Swen, Jesse J, Deenen, Maarten J, Schellens, Jan H M, Gelderblom, Hans, Sub Clinical Pharmacology, Pharmacoepidemiology and Clinical Pharmacology
Publikováno v:
European Journal of Cancer, 54, 40-48
European Journal of Cancer, 54, 40. Elsevier Ltd
European Journal of Cancer, 54, 40. Elsevier Ltd
5-Fluorouracil (5-FU) and capecitabine (CAP) are among the most frequently prescribed anticancer drugs. They are inactivated in the liver by the enzyme dihydropyrimidine dehydrogenase (DPD). Up to 5% of the population is DPD deficient and these patie