Zobrazeno 1 - 10
of 42
pro vyhledávání: '"ZHAO LI"'
Publikováno v:
Pharmacological Reports. 73:858-867
Sodium-dependent glucose co-transporter 2 (SGLT2) inhibitor empagliflozin and glucagon-like peptide-1 (GLP-1) receptor agonist liraglutide are characterized as having cardiovascular benefits in patients with type 2 diabetes (T2D). Little is known reg
Autor:
Ze Tao, Tianshan She, Yanru Feng, Shisheng Wang, Heng Li, Xiaofeng Lu, Yan Liang, Zhao Li, Jingqiu Cheng, Hao Yang, Jie Chen, Qiuxiao Shi
Publikováno v:
Theranostics
Chemotherapeutic multidrug resistance (MDR) is the major hindrance for clinical therapy of colorectal cancer (CRC). Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) with selective cytotoxicity might overcome MDR of CRC cells. Unfortuna
Publikováno v:
The American Journal of Chinese Medicine. 49:359-389
Sophora tonkinensis Gagnep. (ST) (Fabaceae) is distributed chiefly in south-central and southeast China and Vietnam. In traditional Chinese medicine theory, the root and rhizome of ST are toxic and mainly used in the treatment of pharyngeal and laryn
Autor:
Si-Qi Dong, Lian-Jing Cao, Tong-Min Wang, Pei-Fen Zhang, Wen-Qiong Xue, Jing-Wen Huang, Yong-Qiao He, Zi-Yi Wu, Xiao-Hui Zheng, Xi-Zhao Li, Wei Hua Jia, Da-Wei Yang, Jiang-Bo Zhang
Publikováno v:
Cancer Research and Treatment : Official Journal of Korean Cancer Association
Purpose Capecitabine is an extensively used oral prodrug of 5-fluorouracil in treatment of colon cancer and is known to cause hand-foot syndrome (HFS). As the target enzyme for capecitabine, thymidylate synthase (TYMS) plays a key role for 5-fluorour
Autor:
Jiang-Bo Zhang, Yong-Qiao He, Wen-Qiong Xue, Wei Hua Jia, Ming-Yuan Chen, Xiao-Hui Zheng, Shen Guoping, Shao-Dan Zhang, Ye-Zhu Hu, Tong-Min Wang, Ruo-Wen Xiao, Ying Sun, Xi-Zhao Li, Da-Wei Yang, Pei-Fen Zhang
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-12 (2020)
Journal of Translational Medicine
Journal of Translational Medicine
Background Radiation-induced oral mucositis (OM) is one of the most common acute complications for head and neck cancer. Severe OM is associated with radiation treatment breaks, which harms successful tumor management. Radiogenomics studies have indi
Autor:
Pei-Fen Zhang, Wei Hua Jia, Xiao-Hui Zheng, Jiang-Bo Zhang, Li-Xia Lu, Ruo-Zheng Wang, Xi-Zhao Li, Ting Zhou
Publikováno v:
Cancer Science
The detection of Epstein‐Barr virus (EBV) DNA load in nasopharyngeal (NP) brushing samples for diagnosis of nasopharyngeal carcinoma (NPC) has attracted great attention. Further improvements that eliminate the need for clinical settings will greatl
Autor:
Changkun Zhang, Yang Wang, Qian Cheng, Xiao Xiang, Shi-Hua Hu, Siqi Wang, Zhao Li, Jiye Zhu, Xiaodong Xun
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-15 (2020)
Journal of Experimental & Clinical Cancer Research : CR
Journal of Experimental & Clinical Cancer Research : CR
Background The mechanism underlying sorafenib resistance in hepatocellular carcinoma (HCC) remains unclear. Accumulating evidence suggests that tumor-initiating cells (TICs) are a pivotal driving force. Both CD44 and Hedgehog signaling play crucial r
RIP3/MLKL pathway‐regulated necroptosis: A new mechanism of paclitaxel‐induced peripheral neuropathy
Publikováno v:
Journal of Biochemical and Molecular Toxicology. 35
Paclitaxel (PTX) chemotherapy treatment often leads to neuropathic pain, which is resistant to available analgesic treatments. Death of cells and neuroinflammatory response are associated with PTX-induced peripheral neuropathy (PIPN). Necroptosis is
Publikováno v:
Bioscience Reports
Mechanical ventilation is extensively adopted in general anesthesia and respiratory failure management, but it can also induce ventilator-induced lung injury (VILI). Therefore, it is of great urgency to explore the mechanisms involved in the VILI pat
Autor:
Shao-Dan Zhang, Jinhong Zhu, Zhenjian Zhuo, Rui-Xi Hua, Wei Hua Jia, Wen-Qiong Xue, Jing He, Xi-Zhao Li
Publikováno v:
Gene. 705:90-94
DNA ligase III (LIG3) has been implicated in the etiology of cancer. However, few studies have accessed the association of LIG3 single nucleotide polymorphisms (SNPs) with gastric cancer risk, especially in Chinese population. The current study was u