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pro vyhledávání: '"Robert Somerville"'
Autor:
Norris Lam, Steven A. Rosenberg, John J. Rossi, James N. Kochenderfer, Adrian Bot, Robert Somerville, James Chih-Hsin Yang, Richard M. Sherry, Steven A. Feldman, Lori McIntyre, Tangying Lu
Publikováno v:
Molecular therapy : the journal of the American Society of Gene Therapy. 25(10)
T cells expressing anti-CD19 chimeric antigen receptors (CARs) can induce complete remissions (CRs) of diffuse large B cell lymphoma (DLBCL). The long-term durability of these remissions is unknown. We administered anti-CD19 CAR T cells preceded by c
Autor:
Steven A. Rosenberg, Tangying Lily Lu, Omar Pugach, Robert Somerville, Steven A. Feldman, James N. Kochenderfer, Marc Better
Publikováno v:
Human gene therapy methods. 27(6)
The treatment of B-cell malignancies by adoptive cell transfer (ACT) of anti-CD19 chimeric antigen receptor T cells (CD19 CAR-T) has proven to be a highly successful therapeutic modality in several clinical trials.(1–6) The anti-CD19 CAR-T cell pro