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Autor:
Tawfiqul Bhuiya, Juan P. Idrovo, Jin Cao, Pooja Navale, Louis J. Auguste, Sudarshana Roychoudhury, Silvat Sheikh-Fayyaz, Hua Guo
Publikováno v:
Clinical Breast Cancer. 21:e638-e646
This study explored human papillomavirus (HPV) amplification in breast benign and malignant lesions by chromogenic in situ hybridization (CISH) and the concordance of p16 expression by immunohistochemistry.The presence of HPV6/11 and HPV16/18 in 33 c
Autor:
Atanas Ignatov, Piotr Czapiewski, Thomas Kalinski, Willi Pieper, Norbert Nass, Johannes Haybaeck
Publikováno v:
Cancer Biomarkers. 32:161-173
BACKGROUND: Neuronatin (NNAT) determined by immunohistochemistry is a negative prognostic biomarker for breast cancer, independent of the major clinicopathological markers. OBJECTIVE: Here, we investigated whether NNAT is also a predictive biomarker
Publikováno v:
Modern Pathology. 34:1738-1749
Invasive stratified mucin-producing carcinoma (ISMC) is a recently described entity of human papillomavirus (HPV)-associated endocervical adenocarcinoma with phenotypic plasticity and aggressive clinical behavior. To identify the cell of origin of IS
Autor:
Mingming Yuan, Bei Wang, Rongrong Chen, Xuefeng Xia, Huang Chen, Dingrong Zhong, Jia Guo, Changxi Wang
Publikováno v:
Human Pathology. 114:90-98
Anaplastic lymphocyte kinase (ALK) rearrangement, a key oncogenic driver promoting the expression of ALK protein in tumor cells, is found in 2%-7% of patients with nonsmall cell lung cancer (NSCLC). ALK fusion is routinely determined with immunohisto
Autor:
Yuichi Takahashi, Ryuta Iwamoto, Yurina Mikasa, Mitsuaki Okodo, Ayaka Shirasaki, Ibu Matsuzaki, Fumiyoshi Kojima, Shin-ichi Murata, Fidele Y. Musangile
Publikováno v:
Cancer Medicine, Vol 10, Iss 16, Pp 5534-5544 (2021)
Cancer Medicine
Cancer Medicine
Background Human papillomavirus (HPV) is a well‐established mucosotropic carcinogen, but its impact on urothelial neoplasm is unclear. We aimed to clarify the clinical and pathological features of HPV‐related urothelial carcinoma (UC). Methods Ti
Autor:
Abdurrahman Aldiab, Ammar C. Al-Rikabi, Khalid Alsaleh, Nashwa Abd El-Aziz, Tareq Salah, Sufia Husain, Maria Arafah
Publikováno v:
Clinical Breast Cancer. 21:e362-e367
Progesterone receptor (PR), estrogen receptor (ER), and human epidermal growth factor receptor 2 (HER2) significantly influence disease prognosis and therapeutic response in patients with breast cancer. Neoadjuvant chemotherapy (NACT) can change the
Autor:
Gary A. Palmer, Caroline G. Epstein, Michael D. Axelson, Michael E. Salazar, Matthew Kase, Martin C. Stumpe, Calvin McCarter, Ashraf T. Hafez, Joyce O'Shaughnessy, Alexandria M. Bobe, Benjamin D. Leibowitz, Ameen A. Salahudeen, Joshua S.K. Bell, Nike Beaubier, Catherine Igartua, Robert Huether, Mark D. Pegram, Louis E. Fernandes, Ruth A. Pe Benito, Sarah Sammons
Publikováno v:
Clinical Breast Cancer. 21:e340-e361
Objective/Background We performed a retrospective analysis of longitudinal real-world data (RWD) from patients with breast cancer to replicate results from clinical studies and demonstrate the feasibility of generating real-world evidence. We also as
Autor:
Jurgen M.J. Piek, Phyllis van der Ploeg, Laura A.M. van Lieshout, Marjolein H.F.M. Lentjes-Beer, Ruud L.M. Bekkers, Steven L. Bosch, Anja van de Stolpe
Publikováno v:
Cellular Oncology (Dordrecht)
Cellular oncology, 44(4), 951-957. Springer
Cellular oncology, 44(4), 951-957. Springer
Purpose Anti-estrogen therapy may be used as a palliative treatment option in high-grade serous ovarian carcinomas (HGSC). However, clinical implementation is limited as the use of estrogen receptor (ER) protein expression by immunohistochemistry rem
Autor:
Christian Röder, Sandra Krüger, Christine Halske, Anna Trauzold, Jan-Paul Gundlach, Anna Willms, Franka Maria Schlegel, Holger Kalthoff, Charlotte Hauser, Thomas E. Becker, Christoph Röcken
Publikováno v:
Journal of Cancer Research and Clinical Oncology
Purpose HMGA2 has frequently been found in benign as well as malignant tumors and a significant association between HMGA2 overexpression and poor survival in different malignancies was described. In pancreatic ductal adenocarcinoma (PDAC), nuclear HM
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-14 (2021)
BMC Cancer
BMC Cancer
Background To examine the value of energetic-spectrum computed tomography (spectral CT) quantitative parameters in renal cell carcinoma (RCC) microvascular angiogenesis. Methods The authors evaluated 32 patients with pathologically confirmed RCC who