Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Guy Garty"'
Autor:
Jacob Raber, Sarah Holden, David J. Brenner, Christina M. Fallgren, Michael M. Weil, Ruby Perez, Guy Garty, Reed Hall, Brian Ponnaiya
Publikováno v:
Radiat Res
During space missions, astronauts experience acute and chronic low-dose-rate radiation exposures. Given the clear gap of knowledge regarding such exposures, we assessed the effects acute and chronic exposure to a mixed field of neutrons and photons a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb249d0c391456e77aa37b59dd7cea2a
https://europepmc.org/articles/PMC8297553/
https://europepmc.org/articles/PMC8297553/
Autor:
Guy Garty, Jay R. Perrier, Helen Turner, David J. Brenner, Monica Pujol-Canadell, Igor Shuryak
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific Reports
Scientific Reports
We implemented machine learning in the radiation biodosimetry field to quantitatively reconstruct neutron doses in mixed neutron + photon exposures, which are expected in improvised nuclear device detonations. Such individualized reconstructions are
VADER: a variable dose-rate external 137Cs irradiator for internal emitter and low dose rate studies
Autor:
Shanaz A. Ghandhi, Sally A. Amundson, Peter F. Caracappa, Evagelia C. Laiakis, David J. Brenner, Rompin Shih, Albert J. Fornace, Qi Wang, David E. Cuniberti, Shad R. Morton, Lubomir B. Smilenov, Thomas L. Morgan, Carlos Bueno-Beti, Helen Turner, Guy Garty, Gary W. Johnson, Yanping Xu, Monica Pujol-Canadell, Robert C. Morton, Simon Joseph
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
In the long term, 137Cs is probably the most biologically important agent released in many accidental (or malicious) radiation disasters. It can enter the food chain, and be consumed, or, if present in the environment (e.g. from fallout), can provide
Autor:
Maria Taveras, Carlos Bueno-Beti, Jay R. Perrier, David J. Brenner, Guy Garty, Qi Wang, Monica Pujol-Canadell, Helen Turner, Igor Shuryak
Publikováno v:
Radiat Environ Biophys
Environmental contamination and ingestion of the radionuclide Cesium-137 ((137)Cs) is a large concern in fallout from a nuclear reactor accident or improvised nuclear device, and highlights the need to develop biological assays for low-dose rate, int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1290ef70f986892ff14628046b10d94a
https://europepmc.org/articles/PMC7441378/
https://europepmc.org/articles/PMC7441378/
Autor:
David J. Brenner, Antonella Bertucci, Igor Shuryak, Jay R. Perrier, Guy Garty, Andrew D. Harken, Lydia Cunha, Maria Taveras, Helen Turner, Monica Pujol Canadell, Mohammad H. Durrani
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Biodosimetry-based individualized reconstruction of complex irradiation scenarios (partial-body shielding and/or neutron + photon mixtures) can improve treatment decisions after mass-casualty radiation-related incidents. We used a high-throughput mic
Publikováno v:
Radiat Res
We developed a fully-automated dicentric chromosome assay (DCA) in multiwell plates. All operations, from sample loading to chromosome scoring, are performed, without human intervention, by the second-generation Rapid Automated Biodosimetry Tool II (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a58e83e1e6ca694ed2cd8ef939668c6
https://europepmc.org/articles/PMC8567107/
https://europepmc.org/articles/PMC8567107/
Autor:
Jay R. Perrier, Lydia Cunha, Helen Turner, Maria Taveras, Monica Pujol Canadell, Antonella Bertucci, David J. Brenner, Igor Shuryak, Guy Garty, Andrew D. Harken, Mohammad H. Durrani
Biodosimetry-based discrimination between homogeneous total-body photon exposure and complex irradiation scenarios (partial-body shielding and/or neutron + photon mixtures) can improve treatment decisions after mass-casualty radiation-related inciden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::333b704213ec19d99a4c83bda0c30d0a
https://doi.org/10.1101/646711
https://doi.org/10.1101/646711
Publikováno v:
Journal of Radiation Research
The cytokinesis-block micronucleus (CBMN) assay is considered to be the most suitable biodosimetry method for automation. Previously, we automated this assay on a commercial robotic biotech high-throughput system (RABiT-II) adopting both a traditiona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c6d2d3b37e488fbdf98089b70c418f1
https://doi.org/10.1101/627596
https://doi.org/10.1101/627596
Publikováno v:
Phys Med Biol
Accuracy and precision in dosimetry is crucial in studies involving animal models. Small animal dosimetry, in particular for protracted exposures to non uniform radiation fields is particularly challanging. We have developed a novel in vivo dosimeter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ac23a5b05fc251d79bfca8fa0853d5e
http://arxiv.org/abs/1904.07311
http://arxiv.org/abs/1904.07311
Autor:
Matthew A. Rodrigues, Jay R. Perrier, Guy Garty, Helen Turner, Qi Wang, Mikhail Repin, Sergey Pampou, Ruth C. Wilkins, David J. Brenner, Lindsay A. Beaton-Green
The cytokinesis-block micronucleus (CBMN) assay has become a fully-validated and standardized method for radiation biodosimetry. The assay is typically performed using microscopy, which is labor intensive, time consuming and impractical after a large
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8408a3a566ed8b8a158ed3b2ee4e119
https://europepmc.org/articles/PMC6483078/
https://europepmc.org/articles/PMC6483078/