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pro vyhledávání: '"William S. Hambright"'
Autor:
Yan Cui, Paul D. Robbins, Chih Yi Lin, William S. Hambright, Wanqun Chen, Palas K. Chanda, Xiaodong Mu, Ling Zhong, Laura J. Niedernhofer, John P. Cooke, Sudheer Ravuri, Jianhua Gu, Johnny Huard, Polina Matre, Chieh Tseng
Publikováno v:
Aging Cell
Hutchinson–Gilford progeria syndrome (HGPS) is caused by the accumulation of mutant prelamin A (progerin) in the nuclear lamina, resulting in increased nuclear stiffness and abnormal nuclear architecture. Nuclear mechanics are tightly coupled to cy