Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Steven Jacobson"'
Autor:
Steven Jacobson, Tianxia Wu, Avindra Nath, Pascal Sati, Vincent Van Pesch, Daniel S. Reich, Marie Théaudin, Irene Cortese, Caroline Pot, Massimo Filippi, Vittorio Martinelli, Peter A. Calabresi, Renaud Du Pasquier, M. Absinta, Pietro Maggi, Govind Nair, Roberta Scotti, Gaetano Perrotta, Bryan Smith, Joan Ohayon
Publikováno v:
Ann Neurol
Annals of Neurology, Vol. 88, no. 5, p. 1034-1042 (2020)
Annals of Neurology, Vol. 88, no. 5, p. 1034-1042 (2020)
In multiple sclerosis (MS), a subset of chronic active white matter lesions are identifiable on magnetic resonance imaging by their paramagnetic rims, and increasing evidence supports their association with severity of clinical disease. We studied th
Publikováno v:
Journal of Neurovirology
Human T-lymphotropic virus type 1 (HTLV-1) is associated with adult T cell leukemia/lymphoma and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). HAM/TSP is an inflammatory disease of the spinal cord and clinically characterized b
Autor:
Steven Jacobson, Mary Alice Allnutt
Publikováno v:
Drug Discovery Today: Disease Models. 32:21-26
Recent studies have brought renewed interest to the hypothesis that infection plays a role in the pathogenesis of Alzheimer’s disease (AD). In particular, herpesviruses such as herpes simplex virus-1 (HSV-1) and human herpesvirus-6 (HHV-6) have had
Autor:
Ashley Vellucci, Raya Massoud, Bonita R. Bryant, Joan Ohayon, Irene Cortese, Nyater Ngouth, Unsong Oh, Bridgette Jeanne Billioux, Steven Jacobson, Yoshimi Enose-Akahata, Thomas A. Waldmann
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 6, Iss 8, Pp 1383-1394 (2019)
Annals of Clinical and Translational Neurology
Annals of Clinical and Translational Neurology
Objective Human T cell lymphotropic virus 1 (HTLV‐1)‐associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a chronic, progressive, neurological disease. Chronic activation of CD8+ T cells, as evidenced by increased spontaneous lymphopro
Publikováno v:
Epilepsy Research. 153:34-39
Infection with Human Herpesvirus-6 (HHV-6) has been associated with different epilepsy syndromes, including febrile seizures and status epilepticus, acute symptomatic seizures secondary to encephalitis and temporal lobe epilepsy. This neurotropic DNA
Autor:
Martina Absinta, Seung Kwon Ha, Nicholas J. Luciano, Steven Jacobson, Pascal Sati, Dragan Maric, Daniel S. Reich, Govind Nair, Nathanael J. Lee, Maria Chiara Monaco
Publikováno v:
Ann Neurol
Accumulating evidence corroborates the role of the "central vein sign" in the radiological diagnosis of multiple sclerosis (MS). Here, we report human magnetic resonance imaging (MRI) and corresponding pathological data that inflammation-dependent in
Autor:
Joan Ohayon, Steven Jacobson, Jun Zhu, Kory R. Johnson, Paolo A. Muraro, Alessandra de Paula Alves Sousa
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports
Scientific Reports
In this study we characterized the TCR repertoire profiles in patients with chronic progressive inflammatory neurological disorders including HAM/TSP, associated with human T-cell lymphotropic virus type I (HTLV-I) infection, and multiple sclerosis (
Publikováno v:
Clin Microbiol Rev
Human herpesvirus 6A (HHV-6A) and human herpesvirus 6B (HHV-6B), collectively termed HHV-6A/B, are neurotropic viruses that permanently infect most humans from an early age. Although most people infected with these viruses appear to suffer no ill eff
Autor:
Irene Cortese, Shila Azodi, Yair Mina, Steven Jacobson, Frances Andrada, Tianxia Wu, Tsemacha Dubuche, Kory R. Johnson, Govind Nair, Ikesinachi Osuorah, Daniel S. Reich, Joan Ohayon
Publikováno v:
NeuroImage: Clinical, Vol 30, Iss, Pp 102680-(2021)
NeuroImage : Clinical
NeuroImage : Clinical
Highlights • Spinal cord atrophy is prevalent across multiple sclerosis phenotypes. • It correlates with disability, especially in relapsing-remitting patients. • This correlation can be demonstrated both cross-sectionally and longitudinally.
Autor:
Steven Jacobson, Joshua Rim, Robert Roger Lebel, Melissa Byler, Klaus Werner, Ariane Soldatos, Luigi Notarangelo, Emily Leibovitch, Mark Gorman
Publikováno v:
Neurology
Immunodysregulation, polyendocrinopathy, and enteropathy, X-linked (IPEX) syndrome is an autoimmune condition caused by mutations in the Forkhead Box P3 ( FOXP3 ) gene, which maps to chromosome Xp11.23 (OMIM #304790).1 It typically presents within th