Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Jakub Tomasik"'
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-11 (2021)
Translational Psychiatry
Translational Psychiatry
Funder: Stanley Medical Research Institute (SMRI); doi: https://doi.org/10.13039/100007123
Mental health disorders are a leading cause of disability worldwide. Challenges such as disease heterogeneity, incomplete characterization of the targets
Mental health disorders are a leading cause of disability worldwide. Challenges such as disease heterogeneity, incomplete characterization of the targets
Autor:
Paula Suárez-Pinilla, Jordan M. Ramsey, Bonnie Auyeug, Volker Arolt, Jantine A. C. Broek, Tillmann Ruland, Marina Rubey, Olya Mikova, Javier Vázquez-Bourgon, Sergi Papiol, Frieder Haenisch, Sabine Bahn, Emiliano Gonzalez-Vioque, Santiago G. Lago, Geertje F. van Rees, Nikolett Kabacs, Jakub Tomasik, Benedicto Crespo-Facorro, Simon Baron-Cohen
Publikováno v:
Brain, Behavior, and Immunity. Volume 91, January 2021, Pages 673-682
UCrea Repositorio Abierto de la Universidad de Cantabria
Universidad de Cantabria (UC)
Digital.CSIC. Repositorio Institucional del CSIC
instname
UCrea Repositorio Abierto de la Universidad de Cantabria
Universidad de Cantabria (UC)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Recent evidence suggests that comorbidities between neuropsychiatric conditions and metabolic syndrome may precede and even exacerbate long-term side-effects of psychiatric medication, such as a higher risk of type 2 diabetes and cardiovascular disea
Autor:
Nitin Rustogi, Jakub Tomasik, Emily K. Bell, Nayra A Martin-Key, Sabine Bahn, Grégoire Thomas, Sureyya Ozcan, Robin Tuytten, Dan Cowell, Jason D. Cooper, Santiago G. Lago, Tim Metcalfe, Pawel Eljasz, Lauren V. Friend, Sung Yeon Sarah Han, Dan-Mircea Mirea, Tony Olmert, Thea Sofie Schei, Lynn P. Farrag, Giles Barton-Owen
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-12 (2021)
Translational Psychiatry
Translational Psychiatry
The vast personal and economic burden of mood disorders is largely caused by their under- and misdiagnosis, which is associated with ineffective treatment and worsening of outcomes. Here, we aimed to develop a diagnostic algorithm, based on an online
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::794f0df223e28101d5de5bf372224af4
https://www.repository.cam.ac.uk/handle/1810/318516
https://www.repository.cam.ac.uk/handle/1810/318516
Autor:
Jordan M. Ramsey, Frieder Haenisch, Olya Mikova, Bonnie Auyeug, Jantine A. C. Broek, Tillmann Ruland, Simon Baron-Cohen, Jakub Tomasik, Nikolett Kabacs, Jason D. Cooper, Paula Suárez-Pinilla, Volker Arolt, Geertje F. van Rees, Santiago G. Lago, Benedicto Crespo-Facorro, Sabine Bahn
Publikováno v:
Lago, S G, Tomasik, J, van Rees, G F, Ramsey, J M, Haenisch, F, Cooper, J D, Broek, J A, Suarez-Pinilla, P, Ruland, T, Auyeung, B, Mikova, O, Kabacs, N, Arolt, V, Baron-Cohen, S, Crespo-Facorro, B & Bahn, S 2018, ' Exploring the neuropsychiatric spectrum using high-content functional analysis of single-cell signaling networks ', Molecular Psychiatry, pp. 1-18 . https://doi.org/10.1038/s41380-018-0123-4
Neuropsychiatric disorders overlap in symptoms and share genetic risk factors, challenging their current classification into distinct diagnostic categories. Novel cross-disorder approaches are needed to improve our understanding of the heterogeneous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eff30939d496f4cd0b4b3a51cfd107b9
https://www.repository.cam.ac.uk/handle/1810/292585
https://www.repository.cam.ac.uk/handle/1810/292585
Autor:
Grégoire Thomas, Giles Barton-Owen, Jason D. Cooper, Jakub Tomasik, Lauren V. Friend, Tony Olmert, Robin Tuytten, Lynn P. Farrag, Sabine Bahn, Dan Cowell, Pawel Eljasz, Santiago G. Lago, Sureyya Ozcan, Sung Yeon Sarah Han, Nitin Rustogi, Emily K. Bell
Publikováno v:
Brain, behavior, and immunity. 90
With less than half of patients with major depressive disorder (MDD) correctly diagnosed within the primary care setting, there is a clinical need to develop an objective and readily accessible test to enable earlier and more accurate diagnosis. The
Autor:
Mathilde S. L. Jakobsen, Louise Vedtofte, Ole Schjerning, Jens J. Holst, Camilla K Svensson, Jimmi Nielsen, Anders Fink-Jensen, Claus Thorn Ekstrøm, Christoph U. Correll, Sabine Bahn, Tina Vilsbøll, Julie R. Larsen, Hans R. Jespersen, Kamuran Koyuncu, Michelle I Jakobsen, Jakub Tomasik, Nitin Rustogi
Publikováno v:
Tomasik, J, Rustogi, N, Larsen, J R, Jakobsen, M I, Svensson, C K, Vedtofte, L, Jakobsen, M S L, Jespersen, H R, Koyuncu, K, Schjerning, O, Nielsen, J, Ekstrøm, C T, Correll, C U, Holst, J J, Vilsbøll, T, Bahn, S & Fink-Jensen, A 2020, ' Leptin Serum Levels are Associated With GLP-1 Receptor Agonist-Mediated Effects on Glucose Metabolism in Clozapine-or Olanzapine-Treated, Prediabetic, Schizophrenia Patients ', Schizophrenia Bulletin Open, vol. 1, no. 1, sgaa044 . https://doi.org/10.1093/schizbullopen/sgaa044
Background We previously demonstrated that the glucagon-like peptide-1 receptor agonist (GLP-1RA) liraglutide significantly reduced glucometabolic disturbances and body weight vs placebo in prediabetic, overweight, or obese schizophrenia-spectrum dis
Autor:
Nitin Rustogi, Jason D. Cooper, Sabine Bahn, Jakub Tomasik, F. Markus Leweke, Nico J.M. van Beveren, Sureyya Ozcan, Sung Yeon Sarah Han
Publikováno v:
Translational Psychiatry
Translational Psychiatry, Vol 9, Iss 1, Pp 1-10 (2019)
Translational Psychiatry, 9:83. Nature Publishing Group
Translational Psychiatry, Vol 9, Iss 1, Pp 1-10 (2019)
Translational Psychiatry, 9:83. Nature Publishing Group
In the present study, to improve the predictive performance of a model and its reproducibility when applied to an independent data set, we investigated the use of multimodel inference to predict the probability of having a complex psychiatric disorde
Autor:
Pawel Eljasz, Dan-Mircea Mirea, Tony Olmert, Giles Barton-Owen, Jakub Tomasik, Jason D. Cooper, Emily K. Bell, Nayra A Martin-Key, Sabine Bahn, Lynn P. Farrag, Daniel Cowell, Sung Yeon Sarah Han, Lauren V. Friend
Publikováno v:
JMIR Mental Health
JMIR Mental Health, Vol 8, Iss 2, p e23813 (2021)
JMIR Mental Health, Vol 8, Iss 2, p e23813 (2021)
Background Web-based assessments of mental health concerns hold great potential for earlier, more cost-effective, and more accurate diagnoses of psychiatric conditions than that achieved with traditional interview-based methods. Objective The aim of
Publikováno v:
Schizophrenia Research, 176(1), 3-13. Elsevier
Schizophrenia is a heterogeneous psychiatric disorder with a broad spectrum of clinical and biological manifestations. Due to the lack of objective tests, the accurate diagnosis and selection of effective treatments for schizophrenia remains challeng
Autor:
Lauren V. Friend, Lynn P. Farrag, Sung Yeon Sarah Han, Pawel Eljasz, Emily K. Bell, Jason D. Cooper, Rhian Lauren Preece, Jakub Tomasik, Sabine Bahn, Sureyya Ozcan, Giles Barton-Owen, Daniel Cowell, Tony Olmert, Nitin Rustogi
Publikováno v:
JMIR Research Protocols
JMIR Research Protocols, Vol 9, Iss 8, p e18453 (2020)
JMIR Research Protocols, Vol 9, Iss 8, p e18453 (2020)
BackgroundMood disorders affect hundreds of millions of people worldwide, imposing a substantial medical and economic burden. Existing diagnostic methods for mood disorders often result in a delay until accurate diagnosis, exacerbating the challenges