Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Hong Quach"'
Autor:
Lisa F. Barcellos, Leslie Benson, Amy Waldman, Benjamin Greenberg, Bianca Weinstock-Guttman, Janace Hart, Mark Gorman, Tanuja Chitnis, Jennifer Graves, Moses Rodriguez, Gregory Aaen, T. Charles Casper, Jan Mendelt Tillema, John W. Rose, Jayne Ness, Emmanuelle Waubant, Xiaorong Shao, Teri Schreiner, Lauren Krupp, Mar Soe, Anita Belman, Hong Quach, Timothy Lotze
Publikováno v:
Multiple sclerosis (Houndmills, Basingstoke, England), vol 26, iss 8
Mult Scler
Mult Scler
Objective:The aim of this study was to determine whether a vitamin D genetic risk score (vitDGRS) is associated with 25-hydroxyvitamin D (25(OH)D) level and multiple sclerosis (MS) relapses in children.Methods:DNA samples were typed for single nucleo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f303f79a4d5ca45ba706e7f3258df925
https://escholarship.org/uc/item/4m24z973
https://escholarship.org/uc/item/4m24z973
Autor:
Tanuja Chitnis, Moses Rodriguez, Emmanuelle Waubant, Ingrid Kockum, Jayne Ness, Lisa F. Barcellos, Jennifer Rubin, Jan M. Tillema, Lauren Krupp, Diana Quach, Stacy J. Caillier, Gregory Aaen, Leslie Benson, Yolanda Harris, T. Charles Casper, Shelly Roalstad, Teri Schreiner, Soe Mar, Tomas Olsson, Jan Hillert, Amy Waldman, Benjamin Greenberg, Milena A. Gianfrancesco, Jennifer Graves, Bianca Weinstock-Guttman, Meghan Candee, Xiaorong Shao, Ling Shen, Anita Belman, Janace Hart, Pernilla Stridh, Timothy Lotze, Brooke Rhead, Ilana Kahn, Mark Gorman, Catherine Schaefer, Lars Alfredsson, John W. Rose, Anna Karin Hedström, Hong Quach
Publikováno v:
Multiple Sclerosis Journal. 24:1825-1834
Background: Strong evidence supports the role of both genetic and environmental factors in pediatric-onset multiple sclerosis (POMS) etiology. Objective: We comprehensively investigated the association between established major histocompatibility com
Autor:
Annette Langer-Gould, Jessica Smith, Jun Wu, Samantha Haraszti, Hong Quach, Robyn M. Lucas, Judith A. James, Lie Hong Chen, Lilyana Amezcua, Lisa F. Barcellos, Anny H. Xiang, Edlin Gonzales
Publikováno v:
Neurology. 89:1330-1337
Objective:To determine whether Epstein-Barr virus (EBV) or cytomegalovirus (CMV) seropositivity is associated with multiple sclerosis (MS) in blacks and Hispanics and to what extent measures of the hygiene hypothesis or breastfeeding could explain th
Autor:
Jennifer Graves, Ellen M. Mowry, Anita Belman, Hong Quach, T. Charles Casper, Emmanuelle Waubant, Janelle A. Noble, Lauren B. Krupp, Lisa F. Barcellos, Xiaorong Shao
Publikováno v:
Multiple Sclerosis Journal. 22:1528-1535
Background:Genetic ancestry, sex, and individual alleles have been associated with multiple sclerosis (MS) susceptibility.Objective:To determine whether established risk factors for disease onset are associated with relapse rate in pediatric MS.Metho
Autor:
Edlin Gonzalez, Anny H. Xiang, Lie H. Chen, Annette Langer-Gould, Jun Wu, Jessica B. Smith, Robyn M. Lucas, Samantha Haraszti, Hong Quach, Lisa F. Barcellos
Publikováno v:
Nutrients, Vol 10, Iss 3, p 268 (2018)
Nutrients; Volume 10; Issue 3; Pages: 268
Nutrients
Nutrients, vol 10, iss 3
Nutrients; Volume 10; Issue 3; Pages: 268
Nutrients
Nutrients, vol 10, iss 3
Multiple sclerosis (MS) incidence and serum 25-hydroxyvitamin D (25OHD) levels vary by race/ethnicity. We examined the consistency of beneficial effects of 25OHD and/or sun exposure for MS risk across multiple racial/ethnic groups. We recruited incid
Autor:
Lars Alfredsson, Xiaorong Shao, Brooke Rhead, Anna Karin Hedström, Lisa F. Barcellos, Hong Quach, M. Maria Glymour, Ling Shen, Alan E. Hubbard, Kari Stefansson, Milena A. Gianfrancesco, Jan Hillert, Tomas Olsson, Catherine Schaefer, Stefan Walter, Ingileif Jonsdottir, Pernilla Strid, Ingrid Kockum
Multiple sclerosis (MS) is an autoimmune disease with both genetic and environmental risk factors. Recent studies indicate that childhood and adolescent obesity double the risk of MS, but this association may reflect unmeasured confounders rather tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::669be3f3127b5818b6fb69f0bad62997
https://europepmc.org/articles/PMC5391720/
https://europepmc.org/articles/PMC5391720/
Autor:
Teri Schreiner, Anna Karin Hedström, Gregory Aaen, T. Charles Casper, Jennifer Rubin, Lars Alfredsson, Brooke Rhead, John W. Rose, Moses Rodriguez, Janace Hart, Soe Mar, Jennifer Graves, Lisa F. Barcellos, Amy Waldman, Benjamin Greenberg, Jan M. Tillema, Diana Quach, Stacy J. Caillier, Ilana Kahn, Emmanuelle Waubant, Tomas Olsson, Mark Gorman, Shelly Roalstad, Meghan Candee, Hong Quach, Xiaorong Shao, Catherine Schaefer, Ling Shen, Yolanda Harris, Jan Hillert, Catherine Metayer, Bianca Weinstock-Guttman, Anita Belman, Jayne Ness, Lauren Krupp, Edison Xu, Tanuja Chitnis, Ingrid Kockum, Maria Bäärnhielm, Timothy Lotze, Leslie Benson, Milena A. Gianfrancesco, Pernilla Stridh
Publikováno v:
Neurology, vol 88, iss 17
Objective:To utilize Mendelian randomization to estimate the causal association between low serum vitamin D concentrations, increased body mass index (BMI), and pediatric-onset multiple sclerosis (MS) using genetic risk scores (GRS).Methods:We constr
Autor:
Bénédicte Dubois, Lucia Corrado, Deborah F. Mason, Allan G. Kermode, Pentti J. Tienari, Annette Bang Oturai, Charles Hillier, Adrian J. Ivinson, Stephen L. Hauser, Ashley Beecham, Jeannette Lechner-Scott, Vincent Thijs, Jonathan L. Haines, Sarah Edkins, Alexander T. Dilthey, Daniele Cusi, Guy Nagels, David A. Hafler, Mark Slee, Petra Nilsson, James S. Wiley, Lou Brundin, Amy Strange, Elizabeth Visser, Mireia Sospedra, Athena Hadjixenofontos, Sergio E. Baranzini, Jenny Link, Robert Andrews, Viola Biberacher, Helle Bach Søndergaard, Vittorio Martinelli, Tomas Olsson, Gillian L Hall, Stephen Sawcer, Stacy J. Caillier, Per Soelberg Sørensen, Céline Bellenguez, Cornelia M. van Duijn, Frauke Zipp, Nikolaos A. Patsopoulos, Cristin McCabe, Colin Freeman, Simon Broadley, Luisa Bernardinelli, Margaret A. Pericak-Vance, Jan Hillert, Wassila Carpentier, Sandip Shaunak, Anne Spurkland, Barnaby Fiddes, Judith Field, Jan Lycke, Christina M. Lill, Federica Esposito, Ioanna Konidari, Elisabeth Gulowsen Celius, Christian Gieger, Helmut Butzkueven, Ling Shen, James F. Wilson, Magdalena Lindén, Tejas S. Shah, Amie Baker, Dionysia K. Xifara, Hong Quach, Laura Bergamaschi, Rogier Q. Hintzen, Jacob L. McCauley, Janna Saarela, J W Thorpe, Christine Lebrun-Frenay, Felix Luessi, Sandra D'Alfonso, B. E. Kendall, Helga Westerlind, Giancarlo Comi, Nathalie Schnetz-Boutaud, Paola Brambilla, Chris Cotsapas, Anders Hamsten, William Camu, Achim Berthele, Kjell-Morten Myhr, Clive Hawkins, Richard Nicholas, James Harley, Carl A. Anderson, Keijo Koivisto, Irene Coman, Neil Robertson, Hakon Hakonarson, Finn Sellebjerg, Fredrik Piehl, Alessia Di Sapio, Loukas Moutsianas, Mehdi Alizadeh, Lars Alfredsson, Catherine Schaefer, David Rog, Virpi Leppa, C. Martin, Bruce A.C. Cree, Christopher Halfpenny, Irina Elovaara, Filippo Martinelli-Boneschi, Cordelia Langford, Hanne F. Harbo, Wim Robberecht, Isabelle Cournu-Rebeix, Steve Vucic, Izaura Lima Bomfim, Irene Y. Frohlich, Michelle Lee, Bertrand Fontaine, Bernhard Hemmer, Eva Zindler, Chris C. A. Spencer, Malin Larsson, Simon Shields, Ilijas Jelcic, Juliane Winkelmann, Jorge R. Oksenberg, Alastair Wilkins, Silvia Delgado, Volker Siffrin, Helena C. Kronsbein, Bruno Brochet, Panos Deloukas, Daniela Galimberti, Nikos Evangelou, Rebecca C. Selter, Maja Jagodic, Martin Duddy, Timothy Harrower, Per Hall, Nadia Barizzone, Siân Price, Matti Pirinen, Pierre-Antoine Gourraud, Thomas M.C. Binder, Giuseppe Liberatore, Mark Lathrop, M.-M. Hoshi, Garrett Hellenthal, Melissa Sorosina, Thomas Korn, Clara Guaschino, Roland Martin, Jeremy Hobart, Marco Salvetti, Peter Donnelly, Ingrid Kockum, An Goris, Alastair Compston, Mariaemma Rodegher, Dorothea Buck, Clara P. Manrique, Christiane Graetz, Benedicte A. Lie, Trevor J. Kilpatrick, Andrew Graham, Anu Kemppinen, Maria Ban, Gil McVean, John Zajicek, Hannah Blackburn, Mary F. Davis, Emilie Sundqvist, Bruce V. Taylor, Maurizio Leone, Lisa F. Barcellos, Fabio Macciardi, Gilles Defer, Vincent Damotte, Satu Männistö, Graeme J. Stewart, Gordon Mazibrada, Inger Lise Mero, Andre Franke, Philip L. De Jager, Verena Grummel, Mauri Reunanen, David R. Booth, Anna Ticca, Angela Jochim, Leentje Cosemans, Julia Y Mescheriakova, Cristina Agliardi, Paola Cavalla, Jeffrey C. Barrett, Sarah E. Hunt, Gavin Band
Publikováno v:
Nature Genetics
Nature Genetics, Nature Publishing Group, 2013, 45 (11), pp.1353-1360. ⟨10.1038/ng.2770⟩
Beecham, A H, Patsopoulos, N A, Xifara, D K, Davis, M F, Kemppinen, A, Cotsapas, C, Shah, T S, Spencer, C, Booth, D, Goris, A, Oturai, A, Saarela, J, Fontaine, B, Hemmer, B, Martin, C, Zipp, F, D'Alfonso, S, Martinelli-Boneschi, F, Taylor, B, Harbo, H F, Kockum, I, Hillert, J, Olsson, T, Ban, M, Oksenberg, J R, Hintzen, R, Barcellos, L F, Agliardi, C, Alfredsson, L, Alizadeh, M, Anderson, C, Andrews, R, Søndergaard, H B, Baker, A, Band, G, Baranzini, S E, Barizzone, N, Barrett, J, Bellenguez, C, Bergamaschi, L, Bernardinelli, L, Berthele, A, Biberacher, V, Binder, T M C, Blackburn, H, Bomfim, I L, Brambilla, P, Broadley, S, Wilson, J F & Henderson, P 2013, ' Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis ', Nature Genetics, vol. 45, no. 11, pp. 1353-60 . https://doi.org/10.1038/ng.2770
Nature genetics
Nature Genetics, 2013, 45 (11), pp.1353-1360. ⟨10.1038/ng.2770⟩
Nature Genetics, 45(11), 1353-+. Nature Publishing Group
Nature Genetics, Nature Publishing Group, 2013, 45 (11), pp.1353-1360. ⟨10.1038/ng.2770⟩
Beecham, A H, Patsopoulos, N A, Xifara, D K, Davis, M F, Kemppinen, A, Cotsapas, C, Shah, T S, Spencer, C, Booth, D, Goris, A, Oturai, A, Saarela, J, Fontaine, B, Hemmer, B, Martin, C, Zipp, F, D'Alfonso, S, Martinelli-Boneschi, F, Taylor, B, Harbo, H F, Kockum, I, Hillert, J, Olsson, T, Ban, M, Oksenberg, J R, Hintzen, R, Barcellos, L F, Agliardi, C, Alfredsson, L, Alizadeh, M, Anderson, C, Andrews, R, Søndergaard, H B, Baker, A, Band, G, Baranzini, S E, Barizzone, N, Barrett, J, Bellenguez, C, Bergamaschi, L, Bernardinelli, L, Berthele, A, Biberacher, V, Binder, T M C, Blackburn, H, Bomfim, I L, Brambilla, P, Broadley, S, Wilson, J F & Henderson, P 2013, ' Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis ', Nature Genetics, vol. 45, no. 11, pp. 1353-60 . https://doi.org/10.1038/ng.2770
Nature genetics
Nature Genetics, 2013, 45 (11), pp.1353-1360. ⟨10.1038/ng.2770⟩
Nature Genetics, 45(11), 1353-+. Nature Publishing Group
International audience; Using the ImmunoChip custom genotyping array, we analyzed 14,498 subjects with multiple sclerosis and 24,091 healthy controls for 161,311 autosomal variants and identified 135 potentially associated regions (P < 1.0 × 10(-4))
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaed6c6a6596c74a380f29f543038e03
https://doi.org/10.1038/ng.2770
https://doi.org/10.1038/ng.2770
Autor:
Jan Hillert, Lisa F. Barcellos, Anna Karin Hedström, Amanda Mok, Tomas Olsson, Milena A. Gianfrancesco, Lars Alfredsson, M. Maria Glymour, Catherine Schaefer, Ingrid Kockum, Maria Bäärnhielm, Jenny Link, Brooke Rhead, Xiaorong Shao, Ling Shen, Alexandra Gyllenberg, Hong Quach
Publikováno v:
Neurology: Genetics
Neurology. Genetics, vol 2, iss 5
Neurology. Genetics, vol 2, iss 5
Objective: We sought to estimate the causal effect of low serum 25(OH)D on multiple sclerosis (MS) susceptibility that is not confounded by environmental or lifestyle factors or subject to reverse causality. Methods: We conducted mendelian randomizat
Autor:
Anny H. Xiang, Robyn M. Lucas, Samantha Haraszti, Jun Wu, Lisa F. Barcellos, Annette Langer-Gould, Edlin Gonzales, Hong Quach, Jessica B. Smith, Lie H. Chen
Publikováno v:
Nutrients, Vol 10, Iss 2, p 184 (2018)
Nutrients
Nutrients; Volume 10; Issue 2; Pages: 184
Nutrients, vol 10, iss 2
Nutrients
Nutrients; Volume 10; Issue 2; Pages: 184
Nutrients, vol 10, iss 2
Blacks have different dominant polymorphisms in the vitamin D-binding protein (DBP) gene that result in higher bioavailable vitamin D than whites. This study tested whether the lack of association between 25-hydroxyvitamin D (25OHD) and multiple scle