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pro vyhledávání: '"Daniel Savic"'
Autor:
Mengxi Sun, Casey T. Weaver, Carson E. Moseley, Colleen J. Winstead, Min Gao, Daniel Savic, Robin D. Hatton, Barbara L. Kee, Richard M. Myers, Duy Pham
Publikováno v:
Cell reports
Cell Reports, Vol 29, Iss 5, Pp 1203-1220.e7 (2019)
Cell Reports, Vol 29, Iss 5, Pp 1203-1220.e7 (2019)
SUMMARY The basic leucine zipper transcription factor activating transcription factor-like (Batf) contributes to transcriptional programming of multiple effector T cells and is required for T helper 17 (Th17) and T follicular helper (Tfh) cell develo
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36501 (2012)
PLoS ONE
PLoS ONE
Genome-wide association studies (GWAS) have repeatedly shown an association between non-coding variants in the TCF7L2 locus and risk for type 2 diabetes (T2D), implicating a role for cis-regulatory variation within this locus in disease etiology. Sup
Autor:
Greta Sokoloff, Marcelo A. Nobrega, Nancy A. Shanahan, Abraham A. Palmer, Margaret G. Distler, Daniel Savic, Stephanie C. Dulawa
Publikováno v:
PLoS ONE
PLoS ONE, Vol 6, Iss 10, p e26897 (2011)
PLoS ONE, Vol 6, Iss 10, p e26897 (2011)
The comorbidity of type 2 diabetes (T2D) with several psychiatric diseases is well established. While environmental factors may partially account for these co-occurrences, common genetic susceptibilities could also be implicated in the confluence of
Publikováno v:
Genome Biology
Distal transcription enhancers are cis-regulatory elements that promote gene expression, enabling spatiotemporal control of genetic programs such as those required in metazoan developmental processes. Because of their importance, their disruption can