Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Thomas F. Schilling"'
Publikováno v:
PLoS Computational Biology
PLoS Computational Biology, Vol 17, Iss 6, p e1009077 (2021)
PLoS computational biology, vol 17, iss 6
PLoS Computational Biology, Vol 17, Iss 6, p e1009077 (2021)
PLoS computational biology, vol 17, iss 6
The vertebrate hindbrain is segmented into rhombomeres (r) initially defined by distinct domains of gene expression. Previous studies have shown that noise-induced gene regulation and cell sorting are critical for the sharpening of rhombomere boundar
Autor:
Lina Meinecke, Adam L. MacLean, David E. Clouthier, Qing Nie, Praveer P. Sharma, Thomas F. Schilling
Publikováno v:
Genesis (New York, N.Y. : 2000), vol 57, iss 1
The mandibular or first pharyngeal arch forms the upper and lower jaws in all gnathostomes. A gene regulatory network that defines ventral, intermediate, and dorsal domains along the dorsal-ventral (D-V) axis of the arch has emerged from studies in z
Autor:
Julian Sosnik, Enrico Gratton, Qing Nie, Christopher Rackauckas, Michelle A. Digman, Likun Zheng, Thomas F. Schilling
Publikováno v:
eLife
Sosnik, J; Zheng, L; Rackauckas, CV; Digman, M; Gratton, E; Nie, Q; et al.(2016). Noise modulation in retinoic acid signaling sharpens segmental boundaries of gene expression in the embryonic zebrafish hindbrain. ELIFE, 5, e14034. doi: 10.7554/eLife.14034. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/8v88t9j4
eLife, Vol 5 (2016)
Sosnik, J; Zheng, L; Rackauckas, CV; Digman, M; Gratton, E; Nie, Q; et al.(2016). Noise modulation in retinoic acid signaling sharpens segmental boundaries of gene expression in the embryonic zebrafish hindbrain. ELIFE, 5, e14034. doi: 10.7554/eLife.14034. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/8v88t9j4
eLife, Vol 5 (2016)
Morphogen gradients induce sharply defined domains of gene expression in a concentration-dependent manner, yet how cells interpret these signals in the face of spatial and temporal noise remains unclear. Using fluorescence lifetime imaging microscopy
Publikováno v:
PLoS genetics, vol 10, iss 10
Le Pabic, P; Ng, C; & Schilling, TF. (2014). Fat-Dachsous Signaling Coordinates Cartilage Differentiation and Polarity during Craniofacial Development. PLoS Genetics, 10(10). doi: 10.1371/journal.pgen.1004726. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/9s28c4js
PLoS Genetics
PLoS Genetics, Vol 10, Iss 10, p e1004726 (2014)
Le Pabic, P; Ng, C; & Schilling, TF. (2014). Fat-Dachsous Signaling Coordinates Cartilage Differentiation and Polarity during Craniofacial Development. PLoS Genetics, 10(10). doi: 10.1371/journal.pgen.1004726. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/9s28c4js
PLoS Genetics
PLoS Genetics, Vol 10, Iss 10, p e1004726 (2014)
Organogenesis requires coordinated regulation of cellular differentiation and morphogenesis. Cartilage cells in the vertebrate skeleton form polarized stacks, which drive the elongation and shaping of skeletal primordia. Here we show that an atypical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab93caffa9520d85ee461d5453ccfee1
https://escholarship.org/uc/item/9s28c4js
https://escholarship.org/uc/item/9s28c4js
Publikováno v:
PLoS Biology
Tuttle, AM; Hoffman, TL; & Schilling, TF. (2014). Rabconnectin-3a Regulates Vesicle Endocytosis and Canonical Wnt Signaling in Zebrafish Neural Crest Migration. PLoS Biology, 12(5). doi: 10.1371/journal.pbio.1001852. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/99d4419f
PLoS Biology, Vol 12, Iss 5, p e1001852 (2014)
PLoS biology, vol 12, iss 5
Tuttle, AM; Hoffman, TL; & Schilling, TF. (2014). Rabconnectin-3a Regulates Vesicle Endocytosis and Canonical Wnt Signaling in Zebrafish Neural Crest Migration. PLoS Biology, 12(5). doi: 10.1371/journal.pbio.1001852. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/99d4419f
PLoS Biology, Vol 12, Iss 5, p e1001852 (2014)
PLoS biology, vol 12, iss 5
A novel role for Rabconnectin-3a in endosome maturation regulates Wnt signaling, migration, and fate specification in zebrafish neural crest cells.
Cell migration requires dynamic regulation of cell–cell signaling and cell adhesion. Both of th
Cell migration requires dynamic regulation of cell–cell signaling and cell adhesion. Both of th
Publikováno v:
Zhang, Lei; Radtke, Kelly; Zheng, Likun; Cai, Anna Q.; Schilling, Thomas F.; & Nie, Qing. (2012). Noise drives sharpening of gene expression boundaries in the zebrafish hindbrain. Molecular Systems Biology, 8, 613. doi: 10.1038/msb.2012.45. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/3mv418m9
Molecular Systems Biology
Molecular Systems Biology
Fluctuations in morphogens often lead to gene expression domains with rough boundaries during development. A mechanism is described whereby intracellular noise can help coordinate cellular decisions during patterning and thereby sharpen expression bo
Publikováno v:
White, Richard J; Nie, Qing; Lander, Arthur D; & Schilling, Thomas F. (2007). Complex Regulation of cyp26a1 Creates a Robust Retinoic Acid Gradient in the Zebrafish Embryo. PLoS Biology, 5(11), e304. doi: 10.1371/journal.pbio.0050304. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/6hd5n65t
PLoS Biology
PLoS Biology, Vol 5, Iss 11, p e304 (2007)
PLoS Biology
PLoS Biology, Vol 5, Iss 11, p e304 (2007)
Positional identities along the anterior–posterior axis of the vertebrate nervous system are assigned during gastrulation by multiple posteriorizing signals, including retinoic acid (RA), fibroblast growth factors (Fgfs), and Wnts. Experimental evi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc83ffc05070ecfe347798c0c08b80fa
http://www.escholarship.org/uc/item/6hd5n65t
http://www.escholarship.org/uc/item/6hd5n65t
Publikováno v:
Current biology : CB. 9(24)
Pharyngeal arches are a prominent and critical feature of the developing vertebrate head. They constitute a series of bulges within which musculature and skeletal elements form; importantly, these tissues derive from different embryonic cell types [1
Publikováno v:
Developmental Biology. (2):277-287
Left‐right (LR) asymmetry of the heart in vertebrates is regulated by early asymmetric signals in the embryo, including the secreted signal Sonic hedgehog (Shh), but less is known about LR asymmetries of visceral organs. Here we show that Shh also