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Autor:
Ricardo Giovannini, Giulia Poggi, Irina Adamcyzk, Christopher R. Pryce, Stefan Just, Diana Kúkeľová, Nagiua Cuomo-Haymour, Rene Amport, Hannes Sigrist
Publikováno v:
Biological Psychiatry Global Open Science. 2:470-479
Background Excessive processing of aversive life events is a major pathology in stress-related anxiety and depressive disorders. Current pharmacological treatments have rather non-specific mechanisms of action. Somatostatin is synthesized and release
Autor:
Xi Zhao, Gangcai Xie, Enkui Duan, Shitao Chen, Fei Sun, Xiaorong Wang, Zhichuan Chen, Shengnan Gong, Mengmeng Sang, Zhiran Li, Yingying Huang, Guishuan Wang
Publikováno v:
Genes & Diseases. 9:1062-1073
As a BET bromodomain inhibitor, JQ1 has been proven have efficacy against a number of different cancers. In terms of male reproduction, JQ1 may be used as a new type of contraceptive, since JQ1 treatment in male mice could lead to germ cell defects a
Autor:
Kozo Kaibuchi, Masaki Sone, Yoshiya Kawaguchi, Shinichiro Taya, Yusuke Seto, Kentaro Ichijo, Shogo Aida, Tomoo Owa, Tomoki Nishioka, Mariko Yamashita, Mikio Hoshino, Satoshi Miyashita
Publikováno v:
EMBO J
During development, neural progenitors are in proliferative and immature states; however, the molecular machinery that cooperatively controls both states remains elusive. Here, we report that cyclin D1 (CCND1) directly regulates both proliferative an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3d1bcf7b666b0b1d0234a2005dfebe1
https://europepmc.org/articles/PMC10106980/
https://europepmc.org/articles/PMC10106980/
Publikováno v:
Neuroscience. 489:34-43
GABAergic interneurons are a highly diverse class of neurons in the mammalian brain with a critical role in orchestrating multiple cognitive functions and maintaining the balance of excitation/ inhibition across neuronal circuitries. In this perspect
Autor:
Jonas Zaman, Irene Tracey, Joachim Vandekerckhove, Francis Tuerlinckx, Katerina Placek, Johan W.S. Vlaeyen, Katja Wiech, Falk Eippert
Publikováno v:
bioXriv
The Journal of Pain, 23(4), 680-692. Churchill Livingstone
The Journal of Pain
The Journal of Pain, 23(4), 680-692. Churchill Livingstone
The Journal of Pain
Prior expectations can bias how we perceive pain. Using a drift diffusion model, we recently showed that this influence is primarily based on changes in perceptual decision-making (indexed as shift in starting point). Only during unexpected applicati
Publikováno v:
bioRxiv
Xiao, Y, Petrucco, L, Hoodless, L J, Portugues, R & Czopka, T 2022, ' Oligodendrocyte precursor cells sculpt the visual system by regulating axonal remodeling ', Nature Neuroscience . https://doi.org/10.1038/s41593-022-01023-7
Nature Neuroscience
Xiao, Y, Petrucco, L, Hoodless, L J, Portugues, R & Czopka, T 2022, ' Oligodendrocyte precursor cells sculpt the visual system by regulating axonal remodeling ', Nature Neuroscience . https://doi.org/10.1038/s41593-022-01023-7
Nature Neuroscience
Many oligodendrocyte precursor cells (OPCs) do not differentiate to form myelin, suggesting additional roles of this cell population. The zebrafish optic tectum contains OPCs in regions devoid of myelin. Elimination of these OPCs impaired precise con
Autor:
Nico Bast, Clara Moreau, Andre F. Marquand, Varun Warrier, Jan K. Buitelaar, Julian Tillmann, Tim Schaefer, Sarah Baumeister, Andreas G. Chiocchetti, Mariam Zabihi, Christine Ecker, Simon Baron-Cohen, Will Spooren, Flavio Dell’Acqua, Claire Leblond, Carolin Moessnang, Afsheen Yousaf, Christian F. Beckmann, Tobias Banaschewski, Guillaume Dumas, Anke Bletsch, Michael V. Lombardo, Luke Mason, Dorothea L. Floris, Antonio M. Persico, Sara Ambrosino, Declan G. Murphy, Charlotte M. Pretzsch, Emily J.H. Jones, Sven Bölte, Caroline Mann, Sarah Durston, Tony Charman, Christine M. Freitag, Freddy Cliquet, Andreas Meyer-Lindenberg, Thomas Bourgeron, Eva Loth, Nick Puts
Publikováno v:
American Journal of Psychiatry
American Journal of Psychiatry, American Psychiatric Publishing, 2021, appi.ajp.2021.2. ⟨10.1176/appi.ajp.2021.20050630⟩
The American Journal of Psychiatry
The American Journal of Psychiatry, 2021, appi.ajp.2021.2. ⟨10.1176/appi.ajp.2021.20050630⟩
American Journal of Psychiatry, 179, 242-254
American Journal of Psychiatry, 179, 3, pp. 242-254
American Journal of Psychiatry, American Psychiatric Publishing, 2021, appi.ajp.2021.2. ⟨10.1176/appi.ajp.2021.20050630⟩
The American Journal of Psychiatry
The American Journal of Psychiatry, 2021, appi.ajp.2021.2. ⟨10.1176/appi.ajp.2021.20050630⟩
American Journal of Psychiatry, 179, 242-254
American Journal of Psychiatry, 179, 3, pp. 242-254
Contains fulltext : 248865.pdf (Publisher’s version ) (Closed access) OBJECTIVE: Autism spectrum disorder (ASD) is accompanied by highly individualized neuroanatomical deviations that potentially map onto distinct genotypes and clinical phenotypes.
Autor:
Paul H. Goodwin, Nuria Morfin, Thu Huong Pham, Tiffany A. Fillier, Ernesto Guzman-Novoa, Raymond Thomas
Publikováno v:
Journal of Advanced Research. 37:75-89
Introduction Honey bees (Apis mellifera) play key roles in food production performing complex behaviors, like self-grooming to remove parasites. However, the lipids of their central nervous system have not been examined, even though they likely play
Publikováno v:
Scientific Reports. 13
Deficits in arousal and stress responsiveness are a feature of numerous psychiatric disorders including depression and anxiety. Arousal is supported by norepinephrine (NE) released from specialized brainstem nuclei, including the locus coeruleus (LC)
Autor:
Rahul Sanwlani, Sai V. Chitti, Taeyoung Kang, Mohashin Pathan, Suresh Mathivanan, Pamali Fonseka, Jan Van Deun, An Hendrix
Publikováno v:
NUCLEIC ACIDS RESEARCH
Nucleic Acids Research
Nucleic Acids Research
Extracellular vesicles (EVs) are membranous vesicles that are released by both prokaryotic and eukaryotic cells into the extracellular microenvironment. EVs can be categorised as exosomes, ectosomes or shedding microvesicles and apoptotic bodies base
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47aee62d24f009c7bead8e3135e75e56