Zobrazeno 1 - 10
of 22
pro vyhledávání: 'Lüllmann-Rauch, Renate'
Autor:
Norbert Frey, Lucie Carrier, Franziska Dierck, Frauke Senger, Gabriele Brunke, Christian Kuhn, Nesrin Schmiedel, Ashraf Yusuf Rangrez, Derk Frank, Susanne Hille, Rainer Will, Samuel Sossalla, Maja Menke, Thomas Eschenhagen, Renate Lüllmann-Rauch, Inga Schmidt, Pia Bünger, Claudia Mack
Publikováno v:
JACC: Basic to Translational Science
Visual Abstract
Highlights • FYCO1, a component of the autophagic machinery, is highly expressed in the heart and a potent inducer of cardiomyocyte autophagy. • Loss of FYCO1 in vivo inhibits adaptation to starvation or biomechanical stress
Highlights • FYCO1, a component of the autophagic machinery, is highly expressed in the heart and a potent inducer of cardiomyocyte autophagy. • Loss of FYCO1 in vivo inhibits adaptation to starvation or biomechanical stress
Autor:
Bernd Knöll, Renate Lüllmann-Rauch, Paul Saftig, Christian Haass, Yasuo Uchiyama, Wolfgang Wurst, Renate Wanner, Anja Capell, Rudi D'Hooge, Georg Werner, Stijn Stroobants, Patrick Lüningschrör, Benedikt Wefers, Daniela Sinske, Soichiro Kakuta, Michael Sendtner, Benjamin Dombert, Markus Damme
Publikováno v:
Cell Reports, Vol 30, Iss 10, Pp 3506-3519.e6 (2020)
Cell reports 30(10), 3506-3519.e6 (2020). doi:10.1016/j.celrep.2020.02.060
Cell reports 30(10), 3506-3519.e6 (2020). doi:10.1016/j.celrep.2020.02.060
Summary: Genetic variations in TMEM106B, coding for a lysosomal membrane protein, affect frontotemporal lobar degeneration (FTLD) in GRN- (coding for progranulin) and C9orf72-expansion carriers and might play a role in aging. To determine the physiol
Autor:
Stefan F. Lichtenthaler, Paul Saftig, Tobias B. Huber, Lukas Heintz, Lisa Seipold, Lisa Schebsdat, Maja T. Lindenmeyer, Renate Lüllmann-Rauch, Sebastian Wetzel, Stephanie Zielinski, Oliver Kretz, Catherine Meyer-Schwesinger, Marlies Sachs, Wiebke Sachs, Julia Reichelt, Thorsten Wiech, Stephan A. Müller
Publikováno v:
Journal of the American Society of Nephrology 32(6), 1389-1408 (2021). doi:10.1681/ASN.2020081213
J Am Soc Nephrol
J Am Soc Nephrol
Background Podocytes embrace the glomerular capillaries with foot processes, which are interconnected by a specialized adherens junction to ultimately form the filtration barrier. Altered adhesion and loss are common features of podocyte injury, whic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cd38702448fa14059c39567c6bc8975
Autor:
Paul Saftig, Sönke Rudnik, Irm Hermans-Borgmeyer, Markus Glatzel, Thuy Linh Nguyen, Christian Bernreuther, Janna Schneppenheim, Bernd Schröder, Renate Lüllmann-Rauch
Publikováno v:
Oncotarget
// Thuy Linh Nguyen 1 , Janna Schneppenheim 2 , Sonke Rudnik 1 , Renate Lullmann-Rauch 2 , Christian Bernreuther 3 , Irm Hermans-Borgmeyer 4 , Markus Glatzel 3 , Paul Saftig 1 and Bernd Schroder 1 1 Biochemical Institute, Christian Albrechts Universi
Autor:
Vivian Adamski, Torben Mentrup, Regina Fluhrer, Martina Haug-Kröper, Uddipta Biswas, Rolf Jessberger, Ronny Heidasch, Verena Dederer, Bernd Schröder, Paul Saftig, Alkmini A Papadopoulou, Rieke Meyer, Stefan F. Lichtenthaler, Johannes Niemeyer, Renate Lüllmann-Rauch, Martin Bergmann, Artur Mayerhofer, Gunther Wennemuth, Marius K. Lemberg, Stephan A. Müller
Publikováno v:
EMBO reports 20(3), e46449 (2019). doi:10.15252/embr.201846449
Signal peptide peptidase (SPP) and the four homologous SPP‐like (SPPL) proteases constitute a family of intramembrane aspartyl proteases with selectivity for type II‐oriented transmembrane segments. Here, we analyse the physiological function of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1418b4ad477efe0f728a4ddd7233c8b6
https://opus.bibliothek.uni-augsburg.de/opus4/frontdoor/index/index/docId/51759
https://opus.bibliothek.uni-augsburg.de/opus4/frontdoor/index/index/docId/51759
Autor:
Gregor Martin, Radislav Sedlacek, Stefan Rose-John, Miryam Müller, R Barikbin, Sebastian Wetzel, Julia Köhn-Gaone, Olga Zbodakova, Renate Lüllmann-Rauch, Paul Saftig, Ivo Leuschner, Birte Wöhner, Gisa Tiegs, Juri Bergmann, Karel Chalupsky, Janina E.E. Tirnitz-Parker, Dirk Schmidt-Arras
Publikováno v:
Oncotarget
// Miryam Muller 1,* , Sebastian Wetzel 1,* , Julia Kohn-Gaone 2 , Karel Chalupsky 3 , Renate Lullmann-Rauch 4 , Roja Barikbin 5 , Juri Bergmann 1,6 , Birte Wohner 1 , Olga Zbodakova 3 , Ivo Leuschner 7 , Gregor Martin 3,9 , Gisa Tiegs 5 , Stefan Ros
Autor:
Norbert Frey, Alexandra Rosskopf, Lynn Christen, Nesrin Schmiedel, Matthias Eden, Ankush Borlepawar, Derk Frank, Renate Lüllmann-Rauch, Ashraf Yusuf Rangrez
Publikováno v:
Cells, Vol 9, Iss 2390, p 2390 (2020)
Cells
Volume 9
Issue 11
Cells
Volume 9
Issue 11
Dysbindin, a schizophrenia susceptibility marker and an essential constituent of BLOC-1 (biogenesis of lysosome-related organelles complex-1), has recently been associated with cardiomyocyte hypertrophy through the activation of Myozap-RhoA-mediated
Autor:
Renate Lüllmann-Rauch, Judith Blanz, Julia Mayerle, Ilya Gukovsky, Samuel W. French, Olga Vagin, Sudarshan R. Malla, Elmira Tokhtaeva, Iskandar Yakubov, Markus M. Lerch, Viola Oorschot, Matthias Sendler, Olga A. Mareninova, David W. Dawson, Judith Klumperman, Anna S. Gukovskaya
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and molecular gastroenterology and hepatology, vol 1, iss 6
ResearcherID
Cellular and Molecular Gastroenterology and Hepatology, Vol 1, Iss 6, Pp 678-694 (2015)
Cellular and molecular gastroenterology and hepatology, 1(6), 678. Elsevier Inc.
Cellular and molecular gastroenterology and hepatology, vol 1, iss 6
ResearcherID
Cellular and Molecular Gastroenterology and Hepatology, Vol 1, Iss 6, Pp 678-694 (2015)
Cellular and molecular gastroenterology and hepatology, 1(6), 678. Elsevier Inc.
Background & Aims: The pathogenic mechanism of pancreatitis is poorly understood. Recent evidence implicates defective autophagy in pancreatitis responses; however, the pathways mediating impaired autophagy in pancreas remain largely unknown. Here, w
PURPOSE. Retinal degeneration is a common feature of several lysosomal storage disorders, including the mucopolysaccharidoses, a group of metabolic disorders that is characterized by widespread accumulation of glycosaminoglycans due to lysosomal enzy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a899de0b25eb16d98389942cb29a949
https://pub.uni-bielefeld.de/record/2904124
https://pub.uni-bielefeld.de/record/2904124
Autor:
Franziska Dierck, Renate Lüllmann-Rauch, Dieter Adam, Norbert Frey, Sabine Adam-Klages, Constantin Kühl, Justyna Sosna, Susanne Hille, Christian Kuhn
Publikováno v:
Cardiovascular research. 110(3)
Aims Down syndrome-associated dual-specificity tyrosine-(Y)-phosphorylation-regulated kinase 1A (DYRK1A) is a ubiquitously expressed protein kinase. Up to date a variety of targets have been identified, establishing a key role for Dyrk1a in selected