Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Yate-Ching Yuan"'
Autor:
Susanne G. Warner, Sang-In Kim, Haiyong Han, Shyambabu Chaurasiya, Annie Yang, Anthony K. Park, Daniel D. Von Hoff, Zhifang Zhang, Yuman Fong, Yanghee Woo, Zheng Liu, Jianming Lu, Yate-Ching Yuan
Publikováno v:
Cancer Gene Ther
Immunotherapeutic strategies that combine oncolytic virus (OV) and immune checkpoint inhibitors have the potential to overcome treatment resistance in pancreatic ductal adenocarcinoma (PDAC), one of the least immunogenic solid tumors. Oncolytic viral
Autor:
Zheng Liu, Karen S. Aboody, Connor Burke, Min Li, Yuman Fong, Jianming Lu, Yate-Ching Yuan, Rachael Mooney, Jennifer Batalla-Covello, Yvonne R. Cornejo, Asma Abdul Majid, Mohamed Hammad, Thanh H. Dellinger, Nanhai G. Chen
Publikováno v:
Molecular Therapy: Oncolytics, Vol 18, Iss, Pp 326-334 (2020)
Molecular Therapy Oncolytics
Molecular Therapy Oncolytics
Oncolytic virotherapy represents a promising approach for treating recurrent and/or drug-resistant ovarian cancer. However, its successful application in the clinic has been hampered by rapid immune-mediated clearance, which reduces viral delivery to
Autor:
Rakhshanda Layeequr Rahman, Jihyun Lee, Sharad S. Singhal, Sharda P. Singh, Hongzhi Li, Philip Palade, Chhanda Bose, Jonathan Kopel, Catherine Jones, Sanjay Awasthi, Yate-Ching Yuan, Ashly Hindle
Publikováno v:
Cancers, Vol 13, Iss 3329, p 3329 (2021)
Cancers
Volume 13
Issue 13
Cancers
Volume 13
Issue 13
Simple Summary Rlip knockout has been reported to prevent cancer in highly cancer-susceptible mice lacking p53, and Rlip knockdown kills many types of cancer cells. In humans, breast cancer shows diverse characteristics, including HER2-driven subtype
Autor:
Daniel Schmolze, Yate-Ching Yuan, Yuan Yuan, Feng-Mao Lin, Zheng Liu, Paul Frankel, John H. Yim, Wei Wen, Zhen Chen, Susan E. Yost, Peiguo Chu
Publikováno v:
Oncotarget
Background: Metastatic triple negative breast cancer (mTNBC) is a heterogeneous disease with poor prognosis. Molecular evolution of TNBC through chemotherapy selection pressure is well recognized but poorly understood. PI3K/AKT/mTOR is one of the mos
CCNE1 amplification is associated with poor prognosis in patients with triple negative breast cancer
Autor:
Zi-Ming Zhao, Jeffrey H. Chuang, Xiwei Wu, Katherine E. Hutchinson, Sierra Min Li, Javad Noorbakhsh, Zheng Liu, Radia M. Johnson, Yuan Yuan, Susan E. Yost, Yate-Ching Yuan, Charles Warden
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-11 (2019)
BMC Cancer
BMC Cancer
Background Triple negative breast cancer (TNBC) is aggressive with limited treatment options upon recurrence. Molecular discordance between primary and metastatic TNBC has been observed, but the degree of biological heterogeneity has not been fully e
Autor:
Henry Palangdao Igid, Lokesh Dalasanur Nagaprashantha, William C. Green, Vijay S. Tonk, David Berz, Lukman Tijani, Yogesh C. Awasthi, Aditya Rajan, Zheng Liu, Sharad S. Singhal, Yate-Ching Yuan, Hongzhi Li, Jyotsana Singhal, Sharda P. Singh, Sanjay Awasthi
Publikováno v:
Oncotarget
Scopus-Elsevier
Scopus-Elsevier
In previous studies, we found that 2'-hydroxyflavonone (2HF), a citrus flavonoid, inhibits the growth of renal cell carcinoma in a VHL-dependent manner. This was associated with the inhibition of glutathione S-transferases (GSTs), the first step enzy
Autor:
Zhaohui Feng, Yate-Ching Yuan, Nicole Mattson, Mingli Li, Kevin Yining Chen, Steven T. Rosen, Xi Wang, Markus Müschen, Anthony K. N. Chan, Xiaobao Xu, Qiao Liu, Jinhui Wang, Wei Lu, Hongzhi Li, Kazuya Miyashita, Christopher D. Delaney, Chun-Wei Chen, Lu Yang, Jianjun Chen, Yadira M. Soto-Feliciano, Scott A. Armstrong, Sheela Pangeni Pokharel, David Horne, Gang Xiao, Takayuki Hoshii, Sandra Li
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Identification of novel functional domains and characterization of detailed regulatory mechanisms in cancer-driving genes is critical for advanced cancer therapy. To date, CRISPR gene editing has primarily been applied to defining the role of individ
Autor:
Keane K Y Lai, Aurelia Lugea, Jia-Ling Teo, Mingtian Che, Laleh G. Melstrom, Yate-Ching Yuan, Soo-Mi Kweon, Stephen J. Pandol, Richard T. Waldron, Raul Urrutia
Publikováno v:
Cancers, Vol 12, Iss 1476, p 1476 (2020)
Cancers
Cancers
Background: Although cyclic AMP-response element binding protein-binding protein (CBP)/β-catenin signaling is known to promote proliferation and fibrosis in various organ systems, its role in the activation of pancreatic stellate cells (PSCs), the k
Autor:
Yate-Ching Yuan, Ajay Goel, Laleh G. Melstrom, Lily L. Lai, Yanghee Woo, Mustafa Raoof, Yuman Fong, Philip H.G. Ituarte, I. Benjamin Paz, Haiqing Li, Amir Ali Khan
Publikováno v:
Annals of surgical oncology. 28(2)
The rise in the incidence of gastric cancer (GC) and colorectal cancer (CRC) in young adults (YA) remains unexplained. We aim to identify differences in these malignancies between YA and older patients. We retrospectively analyzed the California Canc
Autor:
Herman Wu, Guerry J. Cook, Emily Carnahan, Russell C. Rockne, Stephen J. Forman, Davide Maestrini, Nadia Carlesso, Leo D. Wang, Xiwei Wu, Wei Kai Hua, Yate Ching Yuan, David Frankhouser, Denis O’Meally, Zheng Liu, Ya-Huei Kuo, Guido Marcucci, Jing Qi, Lianjun Zhang, Ayelet Marom, Sergio Branciamore
Publikováno v:
Cancer Res
Temporal dynamics of gene expression inform cellular and molecular perturbations associated with disease development and evolution. Given the complexity of high-dimensional temporal genomic data, an analytic framework guided by a robust theory is nee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ebb8b05c3084eff2a33321070e63703
https://europepmc.org/articles/PMC7416495/
https://europepmc.org/articles/PMC7416495/