Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Wen-Hui Tsai"'
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Whole-exome sequencing (WES) has advantages over the traditional molecular test by screening 20,000 genes simultaneously and has become an invaluable tool for genetic diagnosis in clinical practice. Here, we reported a family with a child and a fetus
Autor:
Lan-Wan Wang, Yung-Chieh Lin, Shan-Tair Wang, Chao-Ching Huang, Kuo-Inn Tsou, Po-Nien Tsao, Shu-Chi Mu, Chyong-Hsin Hsu, Reyin Lien, Hung-Chih Lin, Chien-Chou Hsiao, Chih-Cheng Chen, Yi-Fang Tu, Li-Wen Chen, Chyi-Her Lin, Yuh-Jyh Lin, Lin-Yu Wang, Wen-Hui Tsai, Yi-Yin Chen, Ai-Xi Lin
Publikováno v:
Journal of the Formosan Medical Association, Vol 120, Iss 6, Pp 1314-1323 (2021)
Background: Using regression modeling analysis to investigate the breakpoints of the trends in survival-without-major-neonatal-morbidities (MNM) or -without-neurodevelopmental- impairment (NDI) by year and gestational age (GA) in preterm infants. Met
Autor:
Yin-Hsiu Chien, Siew Lee Wong, Fuu Jen Tsai, Wen Hui Tsai, Ni-Chung Lee, Chaw Liang Chang, Pao Chin Chiu, Wuh-Liang Hwu, Yen Yin Chou
Publikováno v:
Molecular Genetics and Metabolism Reports
Molecular Genetics and Metabolism Reports, Vol 23, Iss, Pp-(2020)
Molecular Genetics and Metabolism Reports, Vol 23, Iss, Pp-(2020)
Objective Enzyme replacement therapy (ERT), the only approved therapy for infantile-onset Pompe disease (IOPD), had heterogeneous clinical effects due to factors such as severity, age at first treatment, dosage, and dosing regimens. We report the cli
Autor:
Hao-Chun Chang, Keng Hsun Hu, Po Lin Tseng, Jiin Haur Chuang, Wei Hsuan Wu, Chin Wei Yeh, Wen Hui Tsai, Yan Shen Shan, Chih Wei Chen, Hung Chi Cheng, Tain Junn Cheng, Wen Tsan Chang, Chin Chih Lin, Hui Ju Tsai, Yuan Ho Lin
Publikováno v:
Oncotarget
Malignant tumors often display an aberrant energy metabolism that relies primarily on glycolysis to produce adenosine triphosphate (ATP) the so-called Warburg effect or aerobic glycolysis. Thus, the elucidation of this energetic alteration in maligna
Autor:
Wen Hui Tsai, Jiin Haur Chuang, Wen Tsan Chang, Chien-Feng Li, Chih Wei Chen, Hung Chi Cheng, Hui Ju Tsai, Meng Che Hsieh, Po Lin Tseng, Tsung Hui Hu, Wei Hsuan Wu
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-16 (2018)
Scientific Reports
Scientific Reports
Changes in TCA cycle enzymes or respiratory activity are possible mechanisms of aerobic glycolysis that contributes to tumor progression. To clarify whether the decrease of succinate dehydrogenase B (SDHB) alters energy metabolism, induces the Warbur
Autor:
Hsin Hua Wang, Yea Shwu Hwang, Yu Chin Chen, Chung-Han Ho, Lin Yu Wang, Wen Hui Tsai, Lan Wan Wang, Hsuan Wen Wang
Publikováno v:
International Journal of Environmental Research and Public Health
Volume 18
Issue 12
International Journal of Environmental Research and Public Health, Vol 18, Iss 6438, p 6438 (2021)
Volume 18
Issue 12
International Journal of Environmental Research and Public Health, Vol 18, Iss 6438, p 6438 (2021)
This study aimed to compare the prevalence rate of atypical sensory processing in late preterm (LP) and term children at two years of age and to further investigate the co-occurrence of atypical sensory processing and behavioral problems (internalizi
Albuterol as an adjunctive treatment to enzyme replacement therapy in infantile-onset Pompe disease☆
Autor:
Ni-Chung Lee, Wen Hui Tsai, Yin-Hsiu Chien, Pao Chin Chiu, Dwight D. Koeberl, Chaw Liang Chang, Fuu Jen Tsai, Wuh-Liang Hwu
Publikováno v:
Molecular Genetics and Metabolism Reports
Molecular Genetics and Metabolism Reports, Vol 11, Iss C, Pp 31-35 (2017)
Molecular Genetics and Metabolism Reports, Vol 11, Iss C, Pp 31-35 (2017)
Background Early initiation of enzyme replacement therapy (ERT) with recombinant human acid alpha-glucosidase is an effective treatment for patients with infantile-onset Pompe disease (IOPD) but cannot prevent a slow progression of myopathy. Albutero
Autor:
Chen-Hao Lee, Wu-Shiun Hsieh, Wuh-Liang Hwu, Feipei Lai, Wen-Hui Tsai, I-Jung Tsai, Ni-Chung Lee, Ting-Fu Chen, En-Ting Wu, Nai-Qi Chen, Hung-Chieh Chou, Yin-Hsiu Chien, Po-Nien Tsao, Shuan-Pei Lin, Yen Yin Chou, Pi-Chuan Fan, Tung-Ming Chang, Hann-Chang Hsiung, Pao-Chin Chiu, C. T. Hsu, Chi-Nien Chen
Publikováno v:
Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies. 20(11)
Critical illnesses caused by undiagnosed genetic conditions are challenging in PICUs. Whole-exome sequencing is a powerful diagnostic tool but usually costly and often fail to arrive at a final diagnosis in a short period. We assessed the feasibility
Autor:
Chih-Kuang Chuang, Ru-Yi Tu, Wen-Hui Tsai, Yun-Ting Lo, Tung-Ming Chang, Chung-Lin Lee, Chia-Ying Chang, Pao Chin Chiu, Hsiang-Yu Lin, Shuan-Pei Lin, Dau-Ming Niu, Ya-Hui Chang
Publikováno v:
Diagnostics, Vol 9, Iss 4, p 140 (2019)
Diagnostics
Volume 9
Issue 4
Diagnostics
Volume 9
Issue 4
Background: The mucopolysaccharidoses (MPSs) are a group of rare lysosomal storage disorders characterized by the accumulation of glycosaminoglycans (GAGs) and which eventually cause progressive damage to various tissues and organs. We developed a fe
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0199355 (2018)
Background First graders born prematurely perform poorly on handwriting speed and legibility. However, whether there are specific legibility factors in which preterm children demonstrate difficulty remains unknown. In addition, handwriting performanc