Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Terrie E. Moffitt"'
Autor:
Felipe Sierra, Gordon J. Lithgow, George A. Kuchel, Avshalom Caspi, Eric Verdin, Daniel Perry, Laura Haynes, S. Jay Olshansky, Richard H. Fortinsky, Terrie E. Moffitt
Publikováno v:
J Am Geriatr Soc
Geriatricians and others must embrace the emerging field of geroscience. Until recently geroscience research was pursued in laboratory animals, but now this field requires specialized expertise in the care of vulnerable older patients with multiple c
Autor:
Avshalom Caspi, Jasmin Wertz, Richie Poulton, Antony Ambler, Francesca Happé, David Mason, Terrie E. Moffitt, Angelica Ronald, Sandhya Ramrakha, Renate Houts
Publikováno v:
Mason, D, Ronald, A, Ambler, A, Caspi, A, Houts, R, Poulton, R, Ramrakha, S, Wertz, J, Moffitt, T E & Happé, F 2021, ' Autistic traits are associated with faster pace of aging : Evidence from the Dunedin study at age 45 ', Autism Research, vol. 14, no. 8, pp. 1684-1694 . https://doi.org/10.1002/aur.2534
Autism Res
Autism Res
Growing evidence indicates that the defining characteristics of autism spectrum disorder (ASD) are distributed throughout the general population; hence, understanding the correlates of aging in people with high autistic traits could shed light on ASD
Autor:
Avshalom Caspi, Terrie E. Moffitt, Louise Arseneault, Daniel W. Belsky, Elsje van Bergen, Jasmin Wertz, Simon R. Cox, Joseph A. Prinz, Eveline L. de Zeeuw, Pietro Biroli, Richie Poulton, David L. Corcoran, Benjamin Williams, Perline Demange, Margherita Malanchini, Elliot M. Tucker-Drob, Abdel Abdellaoui, Karen Sugden, Hill F. Ip, Dorret I. Boomsma, Travis T. Mallard, K. Paige Harden, Benjamin W. Domingue, Kathleen Mullan Harris, Michel G. Nivard, Andrew D. Grotzinger, Colter Mitchell
Publikováno v:
Demange, P A, Malanchini, M, Mallard, T T, Biroli, P, Cox, S R, Grotzinger, A D, Tucker-drob, E M, Abdellaoui, A, Arseneault, L, Van Bergen, E, Boomsma, D I, Caspi, A, Corcoran, D L, Domingue, B W, Harris, K M, Ip, H F, Mitchell, C, Moffitt, T E, Poulton, R, Prinz, J A, Sugden, K, Wertz, J, Williams, B S, De Zeeuw, E L, Belsky, D W, Harden, K P & Nivard, M G 2021, ' Investigating the genetic architecture of noncognitive skills using GWAS-by-subtraction ', Nature Genetics, vol. 53, no. 1, pp. 35-44 . https://doi.org/10.1038/s41588-020-00754-2
Nature genetics, 53(1), 35-44. Nature Publishing Group
Nature Genetics, 53(1), 35-44. Nature Publishing Group
Nature genetics
Nature genetics, 53(1), 35-44. Nature Publishing Group
Nature Genetics, 53(1), 35-44. Nature Publishing Group
Nature genetics
Little is known about the genetic architecture of traits affecting educational attainment other than cognitive ability. We used Genomic Structural Equation Modeling and prior genome-wide association studies (GWAS) of educational attainment (n = 1,131
Autor:
Paul Mitchell, Clement C Y Tham, Louise M Burrell, Avshalom Caspi, Charumathi Sabanayagam, Tien Yin Wong, Jost B. Jonas, Gavin Tan, Jason C. S. Yam, Bamini Gopinath, Mong Li Lee, Tyler Hyungtaek Rim, Chew Yian Chai, Marco Yu, Ling-Jun Li, Carol Y. Cheung, Daniel S W Ting, Omar Farouque, Yih Chung Tham, Terrie E. Moffitt, Richie Poulton, Dejiang Xu, Wynne Hsu, Su Jeong Song, Ya Xing Wang, Ching-Yu Cheng
Publikováno v:
Nature Biomedical Engineering. 5:498-508
Retinal blood vessels provide information on the risk of cardiovascular disease (CVD). Here, we report the development and validation of deep-learning models for the automated measurement of retinal-vessel calibre in retinal photographs, using divers
Autor:
Jordana T. Bell, Claudio D. Stern, Scott D. Gordon, Erik A. Ehli, Silvère M. van der Maarel, Jonathan Mill, Gibran Hemani, Hamdi Mbarek, Juan E. Castillo-Fernandez, Tim D. Spector, Allan F. McRae, Catharina E. M. van Beijsterveldt, Jouke-Jan Hottenga, Veronika V. Odintsova, Nicholas G. Martin, Jaakko Kaprio, Eilis Hannon, P. Eline Slagboom, Gonneke Willemsen, Bastiaan T. Heijmans, Sara N. Lundgren, Josine L. Min, Jenny van Dongen, Miina Ollikainen, Dorret I. Boomsma, Pei-Chien Tsai, Karen Sugden, Charles E. Breeze, Terrie E. Moffitt, Bruno Reversade, Lucia Daxinger, Franziska Paul, Fiona A. Hagenbeek, Eco J. C. de Geus, Grant W. Montgomery, T.D. Spector, Avshalom Caspi
Publikováno v:
Nature communications, 12(1):5618. Nature Publishing Group
Nature Communications
Nature Communications, 12(1):5618, 1-14. Nature Publishing Group
Hemani, G 2021, ' Identical twins carry a persistent epigenetic signature of early genome programming ', Nature Communications, vol. 12, no. 1, 5618 . https://doi.org/10.1038/s41467-021-25583-7
Nature Communications, 12(1). NATURE PORTFOLIO
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
van Dongen, J, Gordon, S D, Odintsova, V V, Mbarek, H, Hagenbeek, F A, van Beijsterveldt, C E M, Jan Hottenga, J, de Geus, E J C, Willemsen, G, Boomsma, D I, Genetics of DNA Methylation Consortium & BIOS Consortium 2021, ' Identical twins carry a persistent epigenetic signature of early genome programming ', Nature Communications, vol. 12, no. 1, 5618, pp. 1-14 . https://doi.org/10.1038/s41467-021-25583-7, https://doi.org/10.1038/s41467-021-25583-7
Nature Communications
Nature Communications, 12(1):5618, 1-14. Nature Publishing Group
Hemani, G 2021, ' Identical twins carry a persistent epigenetic signature of early genome programming ', Nature Communications, vol. 12, no. 1, 5618 . https://doi.org/10.1038/s41467-021-25583-7
Nature Communications, 12(1). NATURE PORTFOLIO
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
van Dongen, J, Gordon, S D, Odintsova, V V, Mbarek, H, Hagenbeek, F A, van Beijsterveldt, C E M, Jan Hottenga, J, de Geus, E J C, Willemsen, G, Boomsma, D I, Genetics of DNA Methylation Consortium & BIOS Consortium 2021, ' Identical twins carry a persistent epigenetic signature of early genome programming ', Nature Communications, vol. 12, no. 1, 5618, pp. 1-14 . https://doi.org/10.1038/s41467-021-25583-7, https://doi.org/10.1038/s41467-021-25583-7
The mechanisms underlying how monozygotic (or identical) twins arise are yet to be determined. Here, the authors investigate this in an epigenome-wide association study, showing that monozygotic twinning has a characteristic DNA methylation signature
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c8782e417f5a11b5e6694746e20eb68
https://pure.amc.nl/en/publications/identical-twins-carry-a-persistent-epigenetic-signature-of-early-genome-programming(73725bc1-8f93-4e02-88e9-189d0ad79157).html
https://pure.amc.nl/en/publications/identical-twins-carry-a-persistent-epigenetic-signature-of-early-genome-programming(73725bc1-8f93-4e02-88e9-189d0ad79157).html
Autor:
Terrie E. Moffitt, Renate Houts, Avshalom Caspi, Wickliffe C. Abraham, Jonathan M. Broadbent, Aaron Reuben, Ahmad R. Hariri, Sandhya Ramrakha, Richie Poulton, Maxwell L. Elliott, Annchen R. Knodt, David Ireland
Publikováno v:
JAMA
Reuben, A, L Elliott, M, Wickliffe C., A, Jonathan, B, Houts, R M, Ireland, D, Knodt, A R, Poulton, R, Ramrakha, S, Hariri, A R, Caspi, A & Moffitt, T 2020, ' Association of Childhood Lead Exposure With MRI Measurements of Structural Brain Integrity in Midlife ', JAMA : the journal of the American Medical Association, vol. 324, no. 19, pp. 1970-1979 . https://doi.org/10.1001/jama.2020.19998
Reuben, A, L Elliott, M, Wickliffe C., A, Jonathan, B, Houts, R M, Ireland, D, Knodt, A R, Poulton, R, Ramrakha, S, Hariri, A R, Caspi, A & Moffitt, T 2020, ' Association of Childhood Lead Exposure With MRI Measurements of Structural Brain Integrity in Midlife ', JAMA : the journal of the American Medical Association, vol. 324, no. 19, pp. 1970-1979 . https://doi.org/10.1001/jama.2020.19998
IMPORTANCE: Childhood lead exposure has been linked to disrupted brain development, but long-term consequences for structural brain integrity are unknown. OBJECTIVE: To test the hypothesis that childhood lead exposure is associated with magnetic reso
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance We leveraged a three-generation approach in 2.1 million Danes to measure the transmission and disruption of multiple health and social disadvantages: poor physical health, poor mental health, social welfare dependency, criminal offending
Autor:
Line Jee Hartmann Rasmussen, Henrik Ullum, Avshalom Caspi, Joseph Dowsett, Søren Brunak, Karina Banasik, Louise Arseneault, Mike Frigge, Kari Stefansson, Erik Sørensen, Karen Sugden, Gudmar Thorleifsson, Sigrun H. Lund, Daniel F. Gudbjartsson, Vinicius Tragante, Kristoffer Sølvsten Burgdorf, Terrie E. Moffitt, Christian Erikstrup, Richie Poulton, Sisse R. Ostrowski, Bjarni Gunnarson, Egil Ferkingstad, Hreinn Stefansson, Lise Wegner Thørner, Lilja Stefansdottir, Thomas Hansen, Magnus K. Magnusson, Jesper Eugen-Olsen, Ole Birger Pedersen
Publikováno v:
Dowsett, J, Ferkingstad, E, Rasmussen, L J H, Thørner, L W, Magnússon, M K, Sugden, K, Thorleifsson, G, Frigge, M, Burgdorf, K S, Ostrowski, S R, Sørensen, E, Erikstrup, C, Pedersen, O B, Hansen, T F, Banasik, K, Brunak, S, DBDS Genomic Consortium, Tragante, V, Lund, S H, Stefansdottir, L, Gunnarson, B, Poulton, R, Arseneault, L, Caspi, A, Moffitt, T E, Gudbjartsson, D, Eugen-Olsen, J, Stefánsson, H, Stefánsson, K, Ullum, H & Nyegaard, M 2021, ' Eleven genomic loci affect plasma levels of chronic inflammation marker soluble urokinase-type plasminogen activator receptor ', Communications Biology, vol. 4, no. 1, pp. 655 . https://doi.org/10.1038/s42003-021-02144-8
Dowsett, J, Ferkingstad, E, Rasmussen, L J H, Thørner, L W, Magnússon, M K, Sugden, K, Thorleifsson, G, Frigge, M, Burgdorf, K S, Ostrowski, S R, Sørensen, E, Erikstrup, C, Pedersen, O B, Hansen, T F, Banasik, K, Brunak, S, DBDS Genomic Consortium, Tragante, V, Lund, S H, Stefansdottir, L, Gunnarson, B, Poulton, R, Arseneault, L, Caspi, A, Moffitt, T E, Gudbjartsson, D, Eugen-Olsen, J, Stefánsson, H, Stefánsson, K & Ullum, H 2021, ' Eleven genomic loci affect plasma levels of chronic inflammation marker soluble urokinase-type plasminogen activator receptor ', Communications Biology, vol. 4, pp. 655 . https://doi.org/10.1038/s42003-021-02144-8
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Dowsett, J, Ferkingstad, E, Rasmussen, L J H, Thørner, L W, Magnússon, M K, Sugden, K, Thorleifsson, G, Frigge, M, Burgdorf, K S, Ostrowski, S R, Sørensen, E, Erikstrup, C, Pedersen, O B, Hansen, T F, Banasik, K, Brunak, S, Tragante, V, Lund, S H, Stefansdottir, L, Gunnarson, B, Poulton, R, Arseneault, L, Caspi, A, Moffitt, T E, Gudbjartsson, D, Eugen-Olsen, J, Stefánsson, H, Stefánsson, K, Ullum, H & DBDS Genomic Consortium 2021, ' Eleven genomic loci affect plasma levels of chronic inflammation marker soluble urokinase-type plasminogen activator receptor ', Communications Biology, vol. 4, no. 1, pp. 655 . https://doi.org/10.1038/s42003-021-02144-8
Dowsett, J, Ferkingstad, E, Rasmussen, L J H, Thørner, L W, Magnússon, M K, Sugden, K, Thorleifsson, G, Frigge, M, Burgdorf, K S, Ostrowski, S R, Sørensen, E, Erikstrup, C, Pedersen, O B, Hansen, T F, Banasik, K, Brunak, S, DBDS Genomic Consortium, Tragante, V, Lund, S H, Stefansdottir, L, Gunnarson, B, Poulton, R, Arseneault, L, Caspi, A, Moffitt, T E, Gudbjartsson, D, Eugen-Olsen, J, Stefánsson, H, Stefánsson, K & Ullum, H 2021, ' Eleven genomic loci affect plasma levels of chronic inflammation marker soluble urokinase-type plasminogen activator receptor ', Communications Biology, vol. 4, no. 1, 655 . https://doi.org/10.1038/s42003-021-02144-8
Communications Biology
Dowsett, J, Ferkingstad, E, Rasmussen, L J H, Thørner, L W, Magnússon, M K, Sugden, K, Thorleifsson, G, Frigge, M, Burgdorf, K S, Ostrowski, S R, Sørensen, E, Erikstrup, C, Pedersen, O B, Hansen, T F, Banasik, K, Brunak, S, DBDS Genomic Consortium, Tragante, V, Lund, S H, Stefansdottir, L, Gunnarson, B, Poulton, R, Arseneault, L, Caspi, A, Moffitt, T E, Gudbjartsson, D, Eugen-Olsen, J, Stefánsson, H, Stefánsson, K & Ullum, H 2021, ' Eleven genomic loci affect plasma levels of chronic inflammation marker soluble urokinase-type plasminogen activator receptor ', Communications Biology, vol. 4, pp. 655 . https://doi.org/10.1038/s42003-021-02144-8
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Dowsett, J, Ferkingstad, E, Rasmussen, L J H, Thørner, L W, Magnússon, M K, Sugden, K, Thorleifsson, G, Frigge, M, Burgdorf, K S, Ostrowski, S R, Sørensen, E, Erikstrup, C, Pedersen, O B, Hansen, T F, Banasik, K, Brunak, S, Tragante, V, Lund, S H, Stefansdottir, L, Gunnarson, B, Poulton, R, Arseneault, L, Caspi, A, Moffitt, T E, Gudbjartsson, D, Eugen-Olsen, J, Stefánsson, H, Stefánsson, K, Ullum, H & DBDS Genomic Consortium 2021, ' Eleven genomic loci affect plasma levels of chronic inflammation marker soluble urokinase-type plasminogen activator receptor ', Communications Biology, vol. 4, no. 1, pp. 655 . https://doi.org/10.1038/s42003-021-02144-8
Dowsett, J, Ferkingstad, E, Rasmussen, L J H, Thørner, L W, Magnússon, M K, Sugden, K, Thorleifsson, G, Frigge, M, Burgdorf, K S, Ostrowski, S R, Sørensen, E, Erikstrup, C, Pedersen, O B, Hansen, T F, Banasik, K, Brunak, S, DBDS Genomic Consortium, Tragante, V, Lund, S H, Stefansdottir, L, Gunnarson, B, Poulton, R, Arseneault, L, Caspi, A, Moffitt, T E, Gudbjartsson, D, Eugen-Olsen, J, Stefánsson, H, Stefánsson, K & Ullum, H 2021, ' Eleven genomic loci affect plasma levels of chronic inflammation marker soluble urokinase-type plasminogen activator receptor ', Communications Biology, vol. 4, no. 1, 655 . https://doi.org/10.1038/s42003-021-02144-8
Communications Biology
Soluble urokinase-type plasminogen activator receptor (suPAR) is a chronic inflammation marker associated with the development of a range of diseases, including cancer and cardiovascular disease. The genetics of suPAR remain unexplored but may shed l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::104197af9a10677e159d96bb9a45b4a9
https://vbn.aau.dk/da/publications/b2efa0ac-88e6-429a-afeb-56a407fd08b7
https://vbn.aau.dk/da/publications/b2efa0ac-88e6-429a-afeb-56a407fd08b7
Autor:
Terrie E. Moffitt, Helen L. Fisher, Stephanie J. Lewis, Avshalom Caspi, Karestan C. Koenen, Louise Arseneault, Andrea Danese, Antony Ambler
Publikováno v:
Br J Psychiatry
BackgroundComplex traumas are traumatic experiences that involve multiple interpersonal threats during childhood or adolescence, such as repeated abuse. These traumas are hypothesised to cause more severe psychopathology and poorer cognitive function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b95d9590951ff91e5452d8a9ac000979
https://europepmc.org/articles/PMC7611677/
https://europepmc.org/articles/PMC7611677/
Autor:
Candice L. Odgers, HonaLee Harrington, Jessie R. Baldwin, Timothy Matthews, Helen L. Fisher, Alan J. Meehan, Sandhya Ramrakha, Terrie E. Moffitt, Richie Poulton, Antony Ambler, Louise Arseneault, Andrea Danese, Avshalom Caspi
Publikováno v:
Baldwin, J R, Caspi, A, Meehan, A J, Ambler, A, Arseneault, L, Fisher, H L, Harrington, H, Matthews, T, Odgers, C L, Poulton, R, Ramrakha, S, Moffitt, T E & Danese, A 2021, ' Population vs Individual Prediction of Poor Health from Results of Adverse Childhood Experiences Screening ', JAMA Pediatrics, vol. 175, no. 4, pp. 385-393 . https://doi.org/10.1001/jamapediatrics.2020.5602
JAMA Pediatrics
JAMA Pediatrics
Key Points Question Can screening for adverse childhood experiences (ACEs) accurately predict individual risk for later health problems? Findings In 2 population-based birth cohorts (with a total of 2927 individuals) growing up 20 years and 20 000 km
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc8b93ca47e2983943b3d8e5084e4f7e
https://kclpure.kcl.ac.uk/en/publications/d11b05a3-bf79-4b3a-a9c9-502f121eac5e
https://kclpure.kcl.ac.uk/en/publications/d11b05a3-bf79-4b3a-a9c9-502f121eac5e