Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Shahram, Bahrami"'
Autor:
Ole A. Andreassen, Srdjan Djurovic, Ingrid Dieset, Shahram Bahrami, Olav Spigset, Nils Eiel Steen, Kevin S. O’Connell, Francesco Bettella, Dennis van der Meer, Lavinia Athanasiu, Katrine K Fjukstad
Publikováno v:
The Pharmacogenomics Journal. 21:574-585
Selective serotonin reuptake inhibitors (SSRIs) are prescribed both to patients with schizophrenia and bipolar disorder. Previous studies have shown associations between SSRI treatment and cardiometabolic alterations. The aim of the present study was
Autor:
Oleksandr Frei, Francesco Bettella, Jan Ivar Røssberg, Guy Hindley, Shahram Bahrami, Anders M. Dale, Kevin S. O’Connell, Alexey A. Shadrin, Olav B. Smeland, Torill Ueland, Florian Krull, Srdjan Djurovic, Nils Eiel Steen, Chun Chieh Fan, Ole A. Andreassen
Publikováno v:
Nature human behaviour
Genome-wide association studies (GWAS) have identified several common genetic variants influencing major depression and general cognitive abilities, but little is known about whether the two share any of their genetic aetiology. Here we investigate s
Autor:
Shahram Bahrami, Alexey A. Shadrin, Kyoko Watanabe, Oleksandr Frei, Olav B. Smeland, Anders M. Dale, Torill Ueland, Kevin S. O’Connell, Florian Krull, Srdjan Djurovic, Francesco Bettella, Danielle Posthuma, Jeanne E. Savage, Ole A. Andreassen, Nils Eiel Steen
Publikováno v:
Smeland, O B, Bahrami, S, Frei, O, Shadrin, A, O’Connell, K, Savage, J, Watanabe, K, Krull, F, Bettella, F, Steen, N E, Ueland, T, Posthuma, D, Djurovic, S, Dale, A M & Andreassen, O A 2020, ' Genome-wide analysis reveals extensive genetic overlap between schizophrenia, bipolar disorder, and intelligence ', Molecular Psychiatry, vol. 25, no. 4, pp. 844-853 . https://doi.org/10.1038/s41380-018-0332-x
Molecular Psychiatry, 25(4), 844-853. Nature Publishing Group
Mol Psychiatry
Molecular Psychiatry
Molecular Psychiatry, 25(4), 844-853. Nature Publishing Group
Mol Psychiatry
Molecular Psychiatry
Schizophrenia (SCZ) and bipolar disorder (BD) are severe mental disorders associated with cognitive impairment, which is considered a major determinant of functional outcome. Despite this, the etiology of the cognitive impairment is poorly understood
Autor:
Asbjørn Holmgren, Srdjan Djurovic, Kari Merete Ersland, Timothy P. Hughes, Lars Johan Axel Hansson, Shahram Bahrami, Ibrahim Akkouh, Silje Skrede, Vidar M. Steen, Ole A. Andreassen
Publikováno v:
Neuropsychopharmacology
Lithium has been the first-line treatment for bipolar disorder (BD) for more than six decades. Although the molecular effects of lithium have been studied extensively and gene expression changes are generally believed to be involved, the specific mec
Autor:
Shahram Bahrami, Torbjørn Elvsåshagen, Lars T. Westlye, Tobias Kaufmann, Vinod Kumar, Oleksandr Frei, Dennis van der Meer, Olav B. Smeland, Alexey A. Shadrin, Ole A. Andreassen
Publikováno v:
Nature Communications, 12(1):2909. Nature Publishing Group
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Nature Communications
The thalamus is a vital communication hub in the center of the brain and consists of distinct nuclei critical for consciousness and higher-order cortical functions. Structural and functional thalamic alterations are involved in the pathogenesis of co
Autor:
Shahram Bahrami, Olav B. Smeland, Kevin S. O’Connell, Torbjørn Elvsåshagen, Oleksandr Frei, Anders M. Dale, Alexey A. Shadrin, Linn Rødevand, Guy Hindley, Trine Vik Lagerberg, Srdjan Djurovic, Yunhan Chu, Nils Eiel Steen, Ole A. Andreassen
Publikováno v:
Translational Psychiatry
Translational Psychiatry, Vol 11, Iss 1, Pp 1-9 (2021)
Translational Psychiatry, Vol 11, Iss 1, Pp 1-9 (2021)
Patients with bipolar disorder (BIP) have a high risk of cardiovascular disease (CVD), despite considerable individual variation. The mechanisms underlying comorbid CVD in BIP remain largely unknown. We investigated polygenic overlap between BIP and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::928bfdd75734f36f3ebcdb3ebb17a1f1
https://hdl.handle.net/11250/2768769
https://hdl.handle.net/11250/2768769
Autor:
Anders M. Dale, Olav B. Smeland, Srdjan Djurovic, Nils Eiel Steen, Osman A. B. S. M. Gani, Guy Hindley, Adriano Winterton, Maren Caroline Frogner Werner, Alexey A. Shadrin, Linn Rødevand, Shahram Bahrami, Daniel Quintana, Aihua Lin, Torbjørn Elvsåshagen, Oleksandr Frei, Trine Vik Lagerberg, Kevin S O' Connell, Ole A. Andreassen
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-11 (2021)
Translational Psychiatry
Translational Psychiatry
Clinical and epidemiological evidence suggest that loneliness is associated with severe mental disorders (SMDs) and increases the risk of cardiovascular disease (CVD). However, the mechanisms underlying the relationship between loneliness, SMDs, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ff2e09fdb022e88dbcc8ff33902e52d
http://hdl.handle.net/10852/83348
http://hdl.handle.net/10852/83348
Autor:
Alexey A. Shadrin, Linn Rødevand, Oleksandr Frei, Anders M. Dale, Francesco Bettella, Shahram Bahrami, Ole A. Andreassen, Kevin S. O’Connell, Srdjan Djurovic, Nils Eiel Steen, Guy Hindley, Chun Chieh Fan, Olav B. Smeland
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-10 (2021)
Translational Psychiatry
Translational Psychiatry
Increased risk-taking is a central component of bipolar disorder (BIP) and is implicated in schizophrenia (SCZ). Risky behaviours, including smoking and alcohol use, are overrepresented in both disorders and associated with poor health outcomes. Posi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80bef5130c4e11709a0726df457c9944
https://hdl.handle.net/11250/2780275
https://hdl.handle.net/11250/2780275
Autor:
Shahram Bahrami, Ole A. Andreassen, John Munkhaugen, Kristin Torgersen, Srdjan Djurovic, Kevin S O' Connell, Toril Dammen, Oleksandr Frei, Alexey A. Shadrin, Olav B. Smeland
Publikováno v:
Translational Psychiatry
Translational Psychiatry, Vol 11, Iss 1, Pp 1-13 (2021)
Translational Psychiatry, Vol 11, Iss 1, Pp 1-13 (2021)
Neuroticism is associated with poor health, cardiovascular disease (CVD) risk factors and coronary artery disease (CAD). The conditional/conjunctional false discovery rate method (cond/conjFDR) was applied to genome wide association study (GWAS) summ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d17ace4ac0748a22138c16e02a33c49
https://hdl.handle.net/11250/2778428
https://hdl.handle.net/11250/2778428
Autor:
Rune Jonassen, Geir Selbæk, Peter Kirsch, Hanne F. Harbo, Lars Nyberg, Einar August Høgestøl, Torbjørn Elvsåshagen, Bruno Vellas, Stephanie Le Hellard, Barbara Franke, Karin Persson, Andreas Papassotiropoulos, Birgitte Boye, Lars T. Westlye, Mona K. Beyer, Georg C. Ziegler, Dominique J.-F. de Quervain, Annette Conzelmann, Jaroslav Rokicki, Dennis van der Meer, Dirk J. Heslenfeld, Piotr Sowa, Emanuel Schwarz, Lei Wang, Ingrid Melle, Erik G. Jönsson, Torgeir Moberget, Andreas Reif, Patrizia Mecocci, Catharina A. Hartman, Pieter J. Hoekstra, Pasquale Di Carlo, Erlend Bøen, Lena Flyckt, Sarah Eisenacher, Ulrik Fredrik Malt, Daan van Rooij, Mathias Zink, Jaap Oosterlaan, Alexey A. Shadrin, Helena Fatouros-Bergman, Eric Westman, Paul Pauli, Simon Cervenka, Nils Inge Landrø, Elisabeth Gulowsen Celius, Klaus-Peter Lesch, Magda Tsolaki, Ramona Baur-Streubel, Trine Vik Lagerberg, Marco Papalino, Jan Egil Nordvik, Oleksandr Frei, Asta Håberg, Hilkka Soininen, Luigi Angelo Maglanoc, Iwona Kłoszewska, André Schmidt, Barbara Gelao, Shahram Bahrami, David Coynel, Andreas Meyer-Lindenberg, Deanna M. Barch, Kevin S O' Connell, Vidar M. Steen, Alessandro Bertolino, Ole A. Andreassen, Jan K. Buitelaar, Ingrid Agartz, Tobias Kaufmann, Stefan Borgwardt, Giulio Pergola, Thomas Espeseth, Giuseppe Blasi, Srdjan Djurovic, Dag Alnæs
Publikováno v:
Nature Communications, 11(1):4016. Nature Publishing Group UK
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications, 11:4016, 1-14. Nature Publishing Group
Nature communications, 11(1):4016. Nature Publishing Group
Nature Communications, 11(1):4016. Nature Publishing Group
Nature Communications, 11, 1
Elvsåshagen, T, Bahrami, S, van der Meer, D, Agartz, I, Alnæs, D, Barch, D M, Baur-Streubel, R, Bertolino, A, Beyer, M K, Blasi, G, Borgwardt, S, Boye, B, Buitelaar, J, Bøen, E, Celius, E G, Cervenka, S, Conzelmann, A, Coynel, D, Di Carlo, P, Djurovic, S, Eisenacher, S, Espeseth, T, Fatouros-Bergman, H, Flyckt, L, Franke, B, Frei, O, Gelao, B, Harbo, H F, Hartman, C A, Håberg, A, Heslenfeld, D, Hoekstra, P J, Høgestøl, E A, Jonassen, R, Jönsson, E G, Farde, L, Flyckt, L, Engberg, G, Erhardt S, S, Fatouros-Bergman, H, Cervenka, S, Schwieler, L, Piehl, F, Agartz, I, Collste, K, Victorsson, P, Malmqvist, A, Hedberg, M, Orhan, F, Sellgren, C M, Kirsch, P, Kłoszewska, I, Lagerberg, T V, Landrø, N I, Le Hellard, S, Lesch, K P, Maglanoc, L A, Malt, U F, Mecocci, P, Melle, I, Meyer-Lindenberg, A, Moberget, T, Nordvik, J E, Nyberg, L, Connell, K S O, Oosterlaan, J, Papalino, M, Papassotiropoulos, A, Pauli, P, Pergola, G, Persson, K, de Quervain, D, Reif, A, Rokicki, J, van Rooij, D, Shadrin, A A, Schmidt, A, Schwarz, E, Selbæk, G, Soininen, H, Sowa, P, Steen, V M, Tsolaki, M, Vellas, B, Wang, L, Westman, E, Ziegler, G C, Zink, M, Andreassen, O A, Westlye, L T, Kaufmann, T & Karolinska Schizophrenia Project (KaSP) consortium 2020, ' The genetic architecture of human brainstem structures and their involvement in common brain disorders ', Nature Communications, vol. 11, no. 1, 4016 . https://doi.org/10.1038/s41467-020-17376-1
Karolinska Schizophrenia Project (KaSP) consortium 2020, ' The genetic architecture of human brainstem structures and their involvement in common brain disorders ', Nature Communications, vol. 11, 4016, pp. 1-14 . https://doi.org/10.1038/s41467-020-17376-1
Nature Communications, 11
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications, 11:4016, 1-14. Nature Publishing Group
Nature communications, 11(1):4016. Nature Publishing Group
Nature Communications, 11(1):4016. Nature Publishing Group
Nature Communications, 11, 1
Elvsåshagen, T, Bahrami, S, van der Meer, D, Agartz, I, Alnæs, D, Barch, D M, Baur-Streubel, R, Bertolino, A, Beyer, M K, Blasi, G, Borgwardt, S, Boye, B, Buitelaar, J, Bøen, E, Celius, E G, Cervenka, S, Conzelmann, A, Coynel, D, Di Carlo, P, Djurovic, S, Eisenacher, S, Espeseth, T, Fatouros-Bergman, H, Flyckt, L, Franke, B, Frei, O, Gelao, B, Harbo, H F, Hartman, C A, Håberg, A, Heslenfeld, D, Hoekstra, P J, Høgestøl, E A, Jonassen, R, Jönsson, E G, Farde, L, Flyckt, L, Engberg, G, Erhardt S, S, Fatouros-Bergman, H, Cervenka, S, Schwieler, L, Piehl, F, Agartz, I, Collste, K, Victorsson, P, Malmqvist, A, Hedberg, M, Orhan, F, Sellgren, C M, Kirsch, P, Kłoszewska, I, Lagerberg, T V, Landrø, N I, Le Hellard, S, Lesch, K P, Maglanoc, L A, Malt, U F, Mecocci, P, Melle, I, Meyer-Lindenberg, A, Moberget, T, Nordvik, J E, Nyberg, L, Connell, K S O, Oosterlaan, J, Papalino, M, Papassotiropoulos, A, Pauli, P, Pergola, G, Persson, K, de Quervain, D, Reif, A, Rokicki, J, van Rooij, D, Shadrin, A A, Schmidt, A, Schwarz, E, Selbæk, G, Soininen, H, Sowa, P, Steen, V M, Tsolaki, M, Vellas, B, Wang, L, Westman, E, Ziegler, G C, Zink, M, Andreassen, O A, Westlye, L T, Kaufmann, T & Karolinska Schizophrenia Project (KaSP) consortium 2020, ' The genetic architecture of human brainstem structures and their involvement in common brain disorders ', Nature Communications, vol. 11, no. 1, 4016 . https://doi.org/10.1038/s41467-020-17376-1
Karolinska Schizophrenia Project (KaSP) consortium 2020, ' The genetic architecture of human brainstem structures and their involvement in common brain disorders ', Nature Communications, vol. 11, 4016, pp. 1-14 . https://doi.org/10.1038/s41467-020-17376-1
Nature Communications, 11
Brainstem regions support vital bodily functions, yet their genetic architectures and involvement in common brain disorders remain understudied. Here, using imaging-genetics data from a discovery sample of 27,034 individuals, we identify 45 brainstem