Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Sasinya N. Scott"'
Autor:
Eliezer M. Van Allen, Ilana Rebecca Garcia-Grossman, Azeez Farooki, Irina Ostrovnaya, Matthew I. Milowsky, Brendan Reardon, Asia S. McCoy, Andrew J. Roth, Aravind Bhayankara, Mariel Elena Boyd, Victor McPherson, David B. Solit, Michael F. Berger, Dean F. Bajorin, Philip H. Kim, Hikmat Al-Ahmadie, Gopa Iyer, Jonathan E. Rosenberg, Ashley Marie Regazzi, Sasinya N. Scott
Publikováno v:
Cancer
Background The phosphatidyl 3-inositol kinase (PI3K)/Akt/mechanistic target of rapamycin (mTOR) pathway frequently is activated in patients with urothelial carcinoma (UC). In the current study, the authors performed a phase 2 study evaluating the eff
Autor:
Michael F. Berger, Pier Selenica, Sumit Middha, Donavan T. Cheng, Kathleen A. Burke, Raymond S. Lim, Abhinita Mohanty, Britta Weigelt, Robert A. Soslow, Sasinya N. Scott, Deborah DeLair
Publikováno v:
The Journal of Pathology. 243:230-241
Clear cell carcinoma of the endometrium is a rare type of endometrial cancer that is generally associated with an aggressive clinical behaviour. Here, we sought to define the repertoire of somatic genetic alterations in endometrial clear cell carcino
Autor:
Irina Ostrovnaya, Nancy Bouvier, Oscar Lin, David B. Solit, Gopakumar Iyer, Caroline M. Lin, Bernard H. Bochner, Sasinya N. Scott, Michael F. Berger
Publikováno v:
Cancer Cytopathology. 125:416-426
BACKGROUND Biopsies from patients with high-risk (HR) non–muscle-invasive urothelial carcinoma (NMIUC), especially flat urothelial carcinoma in situ, frequently contain scant diagnostic material or denuded mucosa only, and this precludes further ex
Autor:
Cristina R. Antonescu, Rajesh Kumar, Luc G. T. Morris, Jorge S. Reis-Filho, Alan L. Ho, Michael F. Berger, Bin Xu, Snjezana Dogan, Sasinya N. Scott, Marcia Edelweiss, Alexander Drilon, Nora Katabi, Nancy Y. Lee, Charlotte K.Y. Ng, Lu Wang, Ahmet Zehir
Publikováno v:
Hum Pathol
Summary Salivary duct carcinoma (SDC) is a rare, aggressive malignancy with limited treatment options and poor outcome. Twenty-nine primary resected SDC, including 15 SDC de novo (SDCDN), and 14 SDC ex pleomorphic adenoma (SDCXPA) were subjected to t
Autor:
Ricardo Ramirez, John P. Sfakianos, Neil Desai, Emily C. Zabor, Aditya Bagrodia, H. Al-Ahmadie, Irina Ostrovnaya, Michael F. Berger, Joseph Hreiki, Gopa Iyer, Jonathan E. Rosenberg, Michael J. Zelefsky, David B. Solit, Dean F. Bajorin, Eugene K. Cha, Marisa A. Kollmeier, Bernard H. Bochner, Sasinya N. Scott
Publikováno v:
Cancer. 122:3715-3723
BACKGROUND The authors characterized the genetic landscape of chemoradiation-treated urothelial carcinoma of the bladder (UCB) with the objective of identifying potential correlates of response. METHODS Primary tumors with (n = 8) or without (n = 40)
Autor:
Byron H. Lee, Ricardo Ramirez, Satish K. Tickoo, Michael F. Berger, Emily C. Zabor, Bernard H. Bochner, Irina Ostrovnaya, Rohit Mehra, Maria E. Arcila, Joseph Hreiki, Eugene K. Cha, Anupama Gandhi, Agnes Viale, Sizhi Paul Gao, Barry S. Taylor, David B. Solit, Sasinya N. Scott, Samson W. Fine, Dean F. Bajorin, Ying-Bei Chen, Guido Dalbagni, Aditya Bagrodia, Victor E. Reuter, Anuradha Gopalan, Gopa Iyer, Jonathan E. Rosenberg, Hikmat Al-Ahmadie, Emmet Jordan, Neil Desai
Publikováno v:
Nature Genetics. 48:356-358
Plasmacytoid bladder cancer is an aggressive histologic variant with a high risk of disease-specific mortality. Using whole-exome and targeted sequencing, we find that truncating somatic alterations in the CDH1 gene occur in 84% of plasmacytoid carci
Autor:
Marcus C.B. Tan, David S. Klimstra, Ronak Shah, Vaidehi Jobanputra, Volkan Adsay, Esra Dikoglu, Olca Basturk, Umesh Bhanot, Peter J. Allen, Sasinya N. Scott, Christine A. Iacobuzio-Donahue, Michael F. Berger, Carlie S. Sigel, Kazimierz O. Wrzeszczynski, Gokce Askan
Publikováno v:
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 29(9)
In 2010, the World Health Organization reclassified the entity originally described as intraductal oncocytic papillary neoplasm as the ‘oncocytic subtype’ of intraductal papillary mucinous neoplasm. Although several key molecular alterations of o
Autor:
Brittanie M Millang, Michael F. Berger, Yaelle Tuvy, Jamie Riches, David H. Ilson, David B. Solit, Nikolaus Schultz, Jaclyn F. Hechtman, Sasinya N. Scott, Nancy Bouvier, David P. Kelsen, Maurizio Scaltriti, Barry S. Taylor, Francisco Sanchez-Vega, Pau Castel, Geoffrey Y. Ku, Efsevia Vakiani, Yelena Y. Janjigian, Ritika Kundra, Matthew Margolis
Publikováno v:
Journal of Clinical Oncology. 34:11608-11608
11608Background: Up to 30% of EG adenocarcinomas harbor ERBB2 (HER2) gene amplification or oncoprotein over-expression. While trastuzumab prolongs survival in patients with Stage IV HER2+ EG tumors...