Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Richard D. Semba"'
Autor:
Stephen B. Kritchevsky, Gregory E. Hicks, Tamara B. Harris, Anne R. Cappola, Peggy M. Cawthon, Vilmundur Gudnason, Luigi Ferrucci, Mary Frances Cotch, Gudny Eiriksdottir, Kristine E. Ensrud, Eleanor M. Simonsick, Michelle Shardell, Richard D. Semba, Eric S. Orwoll, Nancy Chiles Shaffer, Jack M. Guralnik
Publikováno v:
Am J Clin Nutr
BACKGROUND: Threshold serum 25-hydroxyvitamin D [25(OH)D] concentrations for extraskeletal outcomes are uncertain and could differ from recommendations (20–30 ng/mL) for skeletal health. OBJECTIVES: We aimed to identify and validate sex-specific th
Autor:
Lisa M Wilson, Karen A. Robinson, Saraniya Tharmarajah, Richard D. Semba, Yuanxi Jia, Debra A. Schaumberg
Publikováno v:
Advances in Nutrition
Lutein, zeaxanthin, and meso-zeaxanthin are the only carotenoids found in the human macula and may have a role in visual function. These carotenoids are reported to protect the retina, and thus vision, as antioxidants and by acting as a blue light fi
Autor:
Toshiko Tanaka, Yusuke Osawa, Luigi Ferrucci, Marta Zampino, Yuko Yamaguchi, Stefania Bandinelli, Richard D. Semba
Publikováno v:
J Gerontol A Biol Sci Med Sci
Anemia is common in older adults and associated with greater morbidity and mortality. The causes of anemia in older adults have not been completely characterized. Although elevated circulating growth and differentiation factor 15 (GDF-15) has been as
Publikováno v:
Journal of Agriculture, Food Systems, and Community Development, Vol 10, Iss 1 (2020)
The COVID-19 pandemic has increased food insecurity, especially among low-income Black and His¬panic families in the United States. Food insecurity is associated with poorer health and higher mortality in adults and greater risk of impaired cognitiv
Autor:
Luigi Ferrucci, Myriam Gorospe, Ceereena Ubaida-Mohien, Nathan Basisty, Alexey E. Lyashkov, Claudio Franceschi, Richard D. Semba, Toshiko Tanaka, Birgit Schilling, Ruin Moaddel
Publikováno v:
Aging Cell
The identification of plasma proteins that systematically change with age and, independent of chronological age, predict accelerated decline of health is an expanding area of research. Circulating proteins are ideal translational “omics” since th
Autor:
Sandra W. Cardoso, Fatima Zulu, Javier R. Lama, Jyoti Pawar, Thomas B. Campbell, Nikhil Gupte, Actg Pearls Study Team, Breno Santos, Amita Gupta, Richard B. Pollard, Nagalingeswaran Kumarasamy, Jonathan E. Golub, Cynthia Riviere, David M. Asmuth, Erin R. Ewald, Khuanchai Supparatpinyo, Umesh G. Lalloo, Nwcs, Cecilia Kanyama, Rupak Shivakoti, Barbara Detrick, Sharlaa Badal-Faesen, James Hakim, Ashwin Balagopal, Richard D. Semba, Wei-Teng Yang
Publikováno v:
Clin Nutr
Summary Background & aims Nutritional deficiency and inflammation may impact CD4+ T cell recovery during combination antiretroviral therapy (cART), particularly in resource-limited settings where malnutrition is prevalent. The aim of this study was t
Autor:
Elisa Fabbri, Luigi Ferrucci, Marta Gonzalez-Freire, Richard D. Semba, Olga D. Carlson, Toshiko Tanaka, Ruin Moaddel, Min Zhu, Pingbo Zhang, Josephine M. Egan
Publikováno v:
The Journals of Gerontology: Series A. 74:129-136
BACKGROUND: Growth and differentiation factors 8 (GDF8) and 11 (GDF11) have attracted attention as targets for rejuvenating interventions. The biological activity of these proteins may be affected by circulating antagonists such as their respective p
Autor:
Eleanor M. Simonsick, Kenneth W. Fishbein, Richard D. Semba, Jennifer A. Schrack, Fatemeh Adelnia, Luigi Ferrucci, Marta Zampino, Richard G. Spencer
Publikováno v:
J Gerontol A Biol Sci Med Sci
Resting metabolic rate (RMR) tends to decline with aging. The age-trajectory of decline in RMR is similar to changes that occur in muscle mass, muscle strength, and fitness, but while the decline in these phenotypes has been related to changes of mit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59209aab92335f2d80989170bbc9c64d
https://europepmc.org/articles/PMC7751004/
https://europepmc.org/articles/PMC7751004/
Autor:
Angelique Biancotto, Giovanna Fantoni, Yusuke Osawa, Julián Candia, Toshiko Tanaka, Luigi Ferrucci, Stefania Bandinelli, Richard D. Semba
Publikováno v:
Aging Cell
Introduction Mobility disability is a powerful indicator of poor health in older adults. The biological and pathophysiological mechanism underlying the development of mobility disability remains unknown. This study conducted a data‐driven discovery
Autor:
Ranjan Sen, Alexey E. Lyashkov, Michelle Shardell, Chee W. Chia, Ravi Tharakan, Ruin Moaddel, Luigi Ferrucci, Ceereena Ubaida-Mohien, Richard D. Semba, Marta Gonzalez-Freire, Myriam Gorospe
Publikováno v:
eLife
eLife, Vol 8 (2019)
eLife, Vol 8 (2019)
A decline of skeletal muscle strength with aging is a primary cause of mobility loss and frailty in older persons, but the molecular mechanisms of such decline are not understood. Here, we performed quantitative proteomic analysis from skeletal muscl