Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Pablo C, Okhuysen"'
Autor:
Adilene Olvera, Kevin W. Garey, Kerri E. Fernandes, Eduardo Yepez Guevara, Javier A. Adachi, Pablo C. Okhuysen, Lily G. Carlin, Samuel L. Aitken, Micah M. Bhatti
Publikováno v:
Clinical Infectious Diseases. 72:e460-e465
BackgroundPatients with cancer are particularly vulnerable to Clostridioides difficile infection (CDI). Guidelines recommend a two-step diagnostic algorithm to differentiate carriers from CDI; however, there are limited data for this approach while i
Autor:
Xiaotao Zhang, Pablo C. Okhuysen, Paul Scheet, Wesley Siu, Gladys Browman, Carrie R. Daniel, Joseph F. Petrosino, Scott Kopetz, Karen Basen-Engquist, Kristi L. Hoffman, Samir M. Hanash
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-11 (2019)
BMC Cancer
BMC Cancer
BackgroundMouse and human studies support the promise of dry beans to improve metabolic health and to lower cancer risk. In overweight/obese patients with a history of colorectal polyps or cancer, the Beans to Enrich the Gut microbiome vs. Obesity’
Publikováno v:
Open Forum Infectious Diseases
Norovirus (NoV) is the leading cause of viral-related diarrhea in cancer patients, in whom it can be chronic, contributing to decreased quality of life, interruption of cancer care, malnutrition, and altered mucosal barrier function. Immunosuppressed
Autor:
Tomoki Nishiguchi, Dimitrios P. Kontoyiannis, Steven M. Holland, Alexandre E. Malek, Lindsey B. Rosen, Pablo C. Okhuysen, George M. Viola, Andrew R. DiNardo
Publikováno v:
MycosesREFERENCES. 64(6)
The development of disseminated cryptococcosis has historically occurred in patients living with advanced human immunodeficiency virus or other immunosuppressive conditions affecting T-cell function. Recently, patients with anti-cytokine neutralising
Autor:
Andrea Delgado, Patricia J. Eifel, Kathleen M. Schmeler, Lilie L. Lin, Anuja Jhingran, Kyoko Yoshida-Court, Megan Mikkelson, Aparna Mitra, Melissa Paola Mezzari, Greyson Biegert, Pablo C. Okhuysen, Lois M. Ramondetta, Tatiana Karpinets, Ann H. Klopp, Lauren E. Colbert, Travis T. Sims, Jianhua Zhang, Joseph F. Petrosino, Travis Solley
Publikováno v:
Int J Radiat Oncol Biol Phys
Purpose Patients receiving pelvic radiation for cervical cancer experience high rates of acute gastrointestinal (GI) toxicity. The association of changes in the gut microbiome with bowel toxicity from radiation is not well characterized. Methods and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2959fd1b075d155a37eb7e1453b3f9c
https://europepmc.org/articles/PMC7932475/
https://europepmc.org/articles/PMC7932475/
Autor:
Andrew Chang, Pablo C. Okhuysen, Prasenjit Dey, Y. Alan Wang, Jianhua Zhang, Yiyun Lin, Elizabeth M. Whitley, Baoli Hu, Kyle A. LaBella, Wen Ting Liao, Asif Rashid, Kalyani R. Patel, Mary K. Estes, Kunal Rai, Zhengdao Lan, Pingping Hou, Christopher Terranova, Di Zhao, Jun Li, Guocan Wang, Sarah E. Blutt, Andrew W. Dupont, Yonathan Lissanu Deribe, Deepavali Chakravarti, Xizeng Mao, Pingna Deng, Xin Liang, Ole Haagen Nielsen, Sharmistha Sarkar, Denise J. Spring, Alison A. Bertuch, Jiexi Li, Eduardo Vilar, Ronald A. DePinho, Noah F. Shroyer, Mamoun Younes
Publikováno v:
Chakravarti, D, Hu, B, Mao, X, Rashid, A, Li, J, Li, J, Liao, W T, Whitley, E M, Dey, P, Hou, P, LaBella, K A, Chang, A, Wang, G, Spring, D J, Deng, P, Zhao, D, Liang, X, Lan, Z, Lin, Y, Sarkar, S, Terranova, C, Deribe, Y L, Blutt, S E, Okhuysen, P, Zhang, J, Vilar, E, Nielsen, O H, Dupont, A, Younes, M, Patel, K R, Shroyer, N F, Rai, K, Estes, M K, Wang, Y A, Bertuch, A A & DePinho, R A 2020, ' Telomere dysfunction activates YAP1 to drive tissue inflammation ', Nature Communications, vol. 11, 4766 . https://doi.org/10.1038/s41467-020-18420-w
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Germline telomere maintenance defects are associated with an increased incidence of inflammatory diseases in humans, yet whether and how telomere dysfunction causes inflammation are not known. Here, we show that telomere dysfunction drives pATM/c-ABL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::540e9b4ba1f7d641278cf2e30ba3d9ce
https://curis.ku.dk/ws/files/251691851/Telomere_dysfunction_activates_YAP1_to_drive.pdf
https://curis.ku.dk/ws/files/251691851/Telomere_dysfunction_activates_YAP1_to_drive.pdf
Autor:
Elizabeth Cebelinski, Tim J. Vickers, Madeline Pashos, F. Matthew Kuhlmann, John Martin, Firdausi Qadri, Makedonka Mitreva, Oscar G. Gómez-Duarte, Pablo C. Okhuysen, Felipe Del Canto, James M. Fleckenstein, Dave Boxrud, David A. Rasko, Tracy H. Hazen, Roberto Vidal
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 11, p e0007825 (2019)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases
Background Enterotoxigenic Escherichia coli (ETEC) cause significant diarrheal morbidity and mortality in children of resource-limited regions, warranting development of effective vaccine strategies. Genetic diversity of the ETEC pathovar has impeded
Autor:
Tenglong Tang, Wenyi Luo, Sattva S. Neelapu, Hamzah Abu-Sbeih, Yinghong Wang, Jonathan L. Curry, Faisal Ali, Phillip S. Ge, Wai Chin Foo, Pablo C. Okhuysen, David M. Richards, Jason R. Westin
Publikováno v:
American journal of clinical oncology. 42(10)
Background Chimeric antigen receptor T-cell (CART) therapy can significantly improve outcomes for patients with certain hematologic malignancies. The most notable drawbacks of CART are cytokine release syndrome and CART-related encephalopathy syndrom
Autor:
Tenglong Tang, Hamzah Abu-Sbeih, Lauren Nicholas Herrera, Pablo C. Okhuysen, Yinghong Wang, Anne Maria P. Chaftari, Robert R. Jenq, Mehmet Altan
Publikováno v:
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-11 (2019)
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-11 (2019)
Background The gut microbiome impacts the efficacy of immune checkpoint inhibitor (ICI) therapy and the development of ICI-mediated diarrhea and/or colitis (IMDC). Antibiotic therapy,especially that with anaerobic activity, has profound effects on th
Publikováno v:
Journal of Clinical Virology. 136:104740
Background Human herpesvirus 6 (HHV-6) can reactivate with immunosuppression and cause central nervous system (CNS) dysfunction. Much of the literature describes cases after hematopoietic stem cell transplantation (HSCT), ranging from encephalitis to