Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Nils Schweingruber"'
Autor:
Christian Gerloff, Nils Schweingruber
Publikováno v:
Der Nervenarzt. 92:115-126
Die Methoden der kunstlichen Intelligenz (KI) halten Einzug in die Medizin. Die KI-assistierte Medizin ist die Zukunft, die es mitzugestalten gilt. Insbesondere supervidiertes, unsupervidiertes und bestarkendes Lernen werden als Methoden eine zentral
Autor:
Nils Schweingruber, Caren Ramien, Alexander Scheffold, Manuel A. Friese, Jan Broder Engler, Stefan M. Gold, Marissa Vignali, Sina C. Rosenkranz, Petra C. Arck, Harlan Robins, Erik Yusko, Kostas Patas, Anne Willing, Christoph Heesen, Catherine Sanders, Kenneth Chan, Stefanie Gamradt, Anja Harrison, Anke Diemert, Eva Tolosa, Ryan O. Emerson
Publikováno v:
Cell Reports, Vol 29, Iss 4, Pp 810-815.e4 (2019)
Summary: Identifying T cell clones associated with human autoimmunity has remained challenging. Intriguingly, many autoimmune diseases, including multiple sclerosis (MS), show strongly diminished activity during pregnancy, providing a unique research
Autor:
Patrick Czorlich, Jan Regelsberger, Nils Ole Schmidt, Alessandra Rünger, Nils Schweingruber, Manfred Westphal, Eva Tolosa, Franz Ricklefs, Malte Mohme, Cecile L. Maire, Thomas Sauvigny, Katrin Lamszus, Marius Marc-Daniel Mader
Publikováno v:
Translational stroke research. 11(6)
The pathophysiology of delayed cerebral ischemia (DCI) after aneurysmal subarachnoid hemorrhage (aSAH) is incompletely understood. Intrathecal activation of inflammatory immune cells is suspected to play a major role for the induction of DCI. The aim
Autor:
Nils Schweingruber, Christine Stadelmann, Dirk Fitzner, Marta Zagrebelsky, Jens Frahm, Francesca Odoardi, Brit Mollenhauer, Takashi Watanabe, Henrike J. Fischer, Corinna Schlosser, Arianna Merlini, Dmitri Lodygin, Michael Haberl, Moritz Hermann, Cassandra Flügel-Koch, Hsin-Fang Chang, Holger M. Reichardt, Sebastian Kügler, Alexander Flügel, Henrike Körner
Publikováno v:
Nature
The grey matter is a central target of pathological processes in neurodegenerative disorders such as Parkinson’s and Alzheimer’s diseases. The grey matter is often also affected in multiple sclerosis, an autoimmune disease of the central nervous
Publikováno v:
Journal of Neuroendocrinology. 24:174-182
Glucocorticoids (GCs) are widely used to treat inflammatory diseases such as multiple sclerosis (MS). They predominantly act through the GC receptor, a member of the nuclear receptor superfamily that controls transcription by several different mechan
Publikováno v:
Molecular and cellular endocrinology. 380(1-2)
Glucocorticoids (GCs) are the most commonly prescribed drugs for the treatment of acute disease bouts in multiple sclerosis (MS) patients. While T lymphocytes were shown to be essential targets of GC therapy, at least in animal models of MS, the mech
Autor:
Anna Karabinskaya, Fred Lühder, Axel Haine, Jan Tuckermann, Jens van den Brandt, Simone Wüst, Nils Schweingruber, Karsten Tiede, Josbert M. Metselaar, Holger M. Reichardt, Ralf Gold
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 187(8)
Glucocorticoids (GCs) are widely used to treat acute relapses of multiple sclerosis (MS). In this study, we demonstrate that liposomal encapsulation augments the therapeutic potency of GCs as they ameliorate experimental autoimmune encephalomyelitis
Autor:
Fred Lühder, Henrike J. Fischer, Mikael Simons, Nils Schweingruber, Holger M. Reichardt, Peter Huppke
Publikováno v:
Journal of Neuroimmunology. 275:60
wildtype peptide SIINFEKL or its altered peptide ligand variants (APLs) exhibiting decreased affinities (SIINFEKL N SIYNFEKL N SIIQFEKL N SIIVFEKL). As read out, we assessed TF-mediated changes of the proliferative T cell response as well as T effect