Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Melissa M Pentony"'
Autor:
Melissa M. Pentony, Sanjay M. Sisodiya, Martin Armstrong, Alistair T. Pagnamenta, Samantha J. L. Knight, Jenny C. Taylor, Dimitrios V Vavoulis, Simona Balestrini, Elizabeth Caruana Galizia
In the context of pharmacogenomics, whole genome sequencing provides a powerful approach for identifying correlations between response variability to specific drugs and genomic polymorphisms in a population, in an unbiased manner. In this study, we e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00ff93f38a28d3c702da708594c9e1a7
http://arxiv.org/abs/1909.10580
http://arxiv.org/abs/1909.10580
Autor:
Joe Harvey, Matteo P. Ferla, Ricky A. Sharma, Jenny C. Taylor, E Giacopuzzi, Pamela J. Kaisaki, McCullagh Jso., H Winter, Melissa M. Pentony, Knight Sjl.
Publikováno v:
Cancers
Volume 11
Issue 12
Volume 11
Issue 12
Intrahepatic cholangiocarcinoma (ICC) is an aggressive cancer arising from the bile ducts with a need for earlier diagnosis and a greater range of treatment options. KRAS/NRAS mutations are common in ICC tumours and 6&ndash
32% of patients also
32% of patients also
Autor:
Nicholas A. Athanasou, Stuart Winter, Richard Colling, Jenny C. Taylor, Kate Ridout, Adrian L. Harris, Erika Kvikstad, Andrew Protheroe, Angela Hamblin, David N. Church, Zsolt Orosz, Anna Schuh, Knight Sjl., Adrienne M. Flanagan, Ketan A. Shah, Niko Popitsch, T Mizani, B. Hassan, Helene Dreau, Melissa M. Pentony, Ahmed Ashour Ahmed, M Parton, Pavlos Antoniou, Dimitris Vavoulis, Ian Tomlinson
Publikováno v:
Cold Spring Harbor Molecular Case Studies
Schuh, A, Dreau, H, Knight, S J L, Ridout, K, Mizani, T, Vavoulis, D, Colling, R, Antoniou, P, Kvikstad, E M, Pentony, M M, Hamblin, A, Protheroe, A, Parton, M, Shah, K A, Orosz, Z, Athanasou, N, Hassan, B, Flanagan, A M, Ahmed, A, Winter, S, Harris, A, Tomlinson, I, Popitsch, N, Church, D & Taylor, J C 2018, ' Clinically actionable mutation profiles in patients with cancer identified by whole-genome sequencing ', Molecular Case Studies, vol. 4, no. 2, pp. a002279 . https://doi.org/10.1101/mcs.a002279
Schuh, A, Dreau, H, Knight, S J L, Ridout, K, Mizani, T, Vavoulis, D, Colling, R, Antoniou, P, Kvikstad, E M, Pentony, M M, Hamblin, A, Protheroe, A, Parton, M, Shah, K A, Orosz, Z, Athanasou, N, Hassan, B, Flanagan, A M, Ahmed, A, Winter, S, Harris, A, Tomlinson, I, Popitsch, N, Church, D & Taylor, J C 2018, ' Clinically actionable mutation profiles in patients with cancer identified by whole-genome sequencing ', Molecular Case Studies, vol. 4, no. 2, pp. a002279 . https://doi.org/10.1101/mcs.a002279
Next-generation sequencing (NGS) efforts have established catalogs of mutations relevant to cancer development. However, the clinical utility of this information remains largely unexplored. Here, we present the results of the first eight patients rec
Autor:
Kevin Drew, Apurva Narechania, Michael D. Purugganan, Patrick Winters, Rob DeSalle, Duncan Penfold-Brown, Richard Bonneau, Melissa M. Pentony
Publikováno v:
Genome Biology and Evolution
Despite its importance, relatively little is known about the relationship between the structure, function, and evolution of proteins, particularly in land plant species. We have developed a database with predicted protein domains for five plant prote