Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Matthew N. Poy"'
Autor:
Katrina J. Binger, Klemens Raile, Diana M. Willmes, Sabrina Geisberger, Michele Solimena, Matthew N. Poy, Martin Neukam, Sabrina Wurmsee, Ralf Dechend, Dmytro Puchkov, Andreas L. Birkenfeld, Dominik N. Müller, Genevieve Nguyen, Thomas Kurth, Sudhir Gopal Tattikota, Fatimunnisa Qadri
Publikováno v:
Proc. Natl. Acad. Sci. U.S.A. 116, 19983-19988 (2019)
Pancreatic β cells store insulin within secretory granules which undergo exocytosis upon elevation of blood glucose levels. Crinophagy and autophagy are instead responsible to deliver damaged or old granules to acidic lysosomes for intracellular deg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::644d6cf759ccae84eed07fcbe2e66df0
https://europepmc.org/articles/PMC6778207/
https://europepmc.org/articles/PMC6778207/
Autor:
Matthew N. Poy
Publikováno v:
Best Practice & Research Clinical Endocrinology & Metabolism. 30:621-628
Recent protocols have been developed to differentiate human stem cells and fibroblasts into insulin-producing cells capable of releasing the hormone in a glucose-stimulated manner. Limitations remain which prevent bringing these protocols to a clinic
Autor:
Tamas L. Horvath, Louise van der Weyden, Chun-Xia Yi, Xin Yan, Valentina Tarallo, Andreas L. Birkenfeld, Dmytro Puchkov, Min Chi Ku, Anne Sophie Carlo, Sonja C. Schriever, Jan Siemens, Volker Haucke, Kun Song, Arnd Heuser, Luis Varela, Sudhir Gopal Tattikota, James F.A. Poulet, Mirko Moroni, Matthew N. Poy, Mirko Trajkovski, Matthias H. Tschöp, Natalia L. Kononenko, Thoralf Niendorf, Leiron Ferrarese, Gaga Kochlamazashvili, Matthias Heinig, Thomas Rathjen, Klara Szigeti-Buck, Sebastian Brachs
Publikováno v:
Nature neuroscience
Nature Neuroscience
Nat. Neurosci. 20, 1096-1103 (2017)
Nature neuroscience, 20(8), 1096-1103. Nature Publishing Group
Nature neuroscience, Vol. 20, No 8 (2017) pp. 1096-1103
Rathjen, T, Yan, X, Kononenko, N L, Ku, M-C, Song, K, Ferrarese, L, Tarallo, V, Puchkov, D, Kochlamazashvili, G, Brachs, S, Varela, L, Szigeti-Buck, K, Yi, C-X, Schriever, S C, Tattikota, S G, Carlo, A S, Moroni, M, Siemens, J, Heuser, A, van der Weyden, L, Birkenfeld, A L, Niendorf, T, Poulet, J F A, Horvath, T L, Tschöp, M H, Heinig, M, Trajkovski, M, Haucke, V & Poy, M N 2017, ' Regulation of body weight and energy homeostasis by neuronal cell adhesion molecule 1 ', Nature Neuroscience, vol. 20, no. 8, pp. 1096-1103 . https://doi.org/10.1038/nn.4590
Nature Neuroscience
Nat. Neurosci. 20, 1096-1103 (2017)
Nature neuroscience, 20(8), 1096-1103. Nature Publishing Group
Nature neuroscience, Vol. 20, No 8 (2017) pp. 1096-1103
Rathjen, T, Yan, X, Kononenko, N L, Ku, M-C, Song, K, Ferrarese, L, Tarallo, V, Puchkov, D, Kochlamazashvili, G, Brachs, S, Varela, L, Szigeti-Buck, K, Yi, C-X, Schriever, S C, Tattikota, S G, Carlo, A S, Moroni, M, Siemens, J, Heuser, A, van der Weyden, L, Birkenfeld, A L, Niendorf, T, Poulet, J F A, Horvath, T L, Tschöp, M H, Heinig, M, Trajkovski, M, Haucke, V & Poy, M N 2017, ' Regulation of body weight and energy homeostasis by neuronal cell adhesion molecule 1 ', Nature Neuroscience, vol. 20, no. 8, pp. 1096-1103 . https://doi.org/10.1038/nn.4590
Susceptibility to obesity is linked to genes regulating neurotransmission, pancreatic beta-cell function and energy homeostasis. Genome-wide association studies have identified associations between body mass index and two loci near cell adhesion mole
Autor:
Varun Pandey, Matthias Selbach, Lena Eliasson, Hans-Hermann Wessels, Jean Hausser, Robert P. Zinzen, Thomas Rathjen, Matthias D. Sury, Inês G. Mollet, Martin Jastroch, Sudhir Gopal Tattikota, Uma D. Kabra, Marc R. Friedländer, Matthias H. Tschöp, Aditya Khedkar, Matthew N. Poy, Mihaela Zavolan, Sebastian Kadener
Publikováno v:
J. Biol. Chem. 290, 20284-20294 (2015)
Journal of Biological Chemistry; 290(33), pp 20284-20294 (2015)
Journal of Biological Chemistry; 290(33), pp 20284-20294 (2015)
In response to fasting or hyperglycemia, the pancreatic β-cell alters its output of secreted insulin; however the pathways governing this adaptive response are not entirely established. While the precise role of microRNAs (miRNAs) is also unclear, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d25305055dc44bba95c561cfa5fda4b3
https://europepmc.org/articles/PMC4536436/
https://europepmc.org/articles/PMC4536436/