Zobrazeno 41 - 50
of 186
pro vyhledávání: '"Kevin J Harrington"'
Autor:
Syed Haider, Robert S. Coffin, Eva Crespo-Rodriguez, Khin Thway, Richard Buus, Alan Melcher, Richard G. Vile, Harriet Whittock, Emmanuel C Patin, Galabina Bozhanova, Kate Newbold, Dae Kim, Katharina F. Bergerhoff, Malin Pedersen, Gareth Muirhead, Martin McLaughlin, Shane Foo, Kevin J. Harrington
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer
BackgroundThe aggressive clinical behavior of poorly differentiated and anaplastic thyroid cancers (PDTC and ATC) has proven challenging to treat, and survival beyond a few months from diagnosis is rare. Although 30%–60% of these tumors contain mut
Autor:
Sara Reis, Intan Hamid, Sophie McGrath, Susannah Stanway, Alicia Okines, Jaishree Bhosle, Vasileios Angelis, Marco Gerlinger, Heba Soliman, Zayd Tippu, Firza Gronthoud, Robin L. Jones, Emma Cottier, Charlotte Fribbens, Jillian Noble, David Watkins, Spyridon Gennatas, Kroopa Joshi, Pablo Nenclares, Kevin J. Harrington
Publikováno v:
European Journal of Cancer
Background In light of the coronavirus disease 2019 (COVID-19) pandemic, cancer centres in the United Kingdom and Europe re-organised their services at an unprecedented pace, and many patients with cancer have had their treatments severely disrupted.
Autor:
Ezra E.W. Cohen, Denis Soulières, Tricia Bal, Lingkang Huang, Barbara Burtness, Deepti Aurora-Garg, Kevin J. Harrington, Kenneth Emancipator, Christophe Le Tourneau, Ramona F. Swaby, Lisa Licitra
Publikováno v:
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 34(3)
Tumor proportion score (TPS) and combined positive score ([CPS] includes immune cells), 2 methods for scoring programmed death ligand 1 (PD-L1) expression, have been used in clinical trials investigating the immune checkpoint inhibitor pembrolizumab
Autor:
Danny Rischin, Barbara Burtness, Holly Brown, Y. Pointreau, Kevin J. Harrington, Makoto Tahara, Lillian L. Siu, Jean-Pascal Machiels, Gustavo Vasconcelos Alves, Behzad Bidadi, Yungan Tao, Christian Simon, Vincent Grégoire, Jonathan D. Cheng, John Waldron, Sercan Aksoy, Marcin Hetnal, Brett G.M. Hughes, Iane Pinto Figueiredo Lima, Joy Yang Ge, Lisa Licitra
Publikováno v:
Future oncology, Vol. 16, no. 18, p. 1235-1243 (2020)
Future oncology (London, England), Vol. 16, no.18, p. 1235-1243 (2020)
Future oncology (London, England), Vol. 16, no.18, p. 1235-1243 (2020)
Current treatment guidelines for patients with locally advanced head and neck squamous cell carcinoma (HNSCC) recommend multimodal treatment, including chemoradiation therapy (CRT) or surgery followed by radiation, with or without chemotherapy. The i
Autor:
Emma King, Priyamal Silva, Derfel Ap Dafydd, Ken Lingley, Gillian Paterson, Cyrus Kerawala, Vinidh Paleri, Kent Yip, Izhar Bagwan, Miranda Payne, Pablo Nenclares, Kevin J. Harrington, Donna Begg, Neil Steven, Nancy Turnbull
Publikováno v:
European journal of cancer (Oxford, England : 1990). 138
The United Kingdom head and neck mucosal melanoma guideline development group used an evidence-based systematic approach to make recommendations in key areas of uncertainty in the field, including accurate diagnosis and staging; the appropriate treat
Autor:
Brian Ng-Cheng-Hin, D. McQuaid, Kate Newbold, Shreerang Bhide, Alex Dunlop, Kee Howe Wong, Christopher M. Nutting, Kevin J. Harrington
Publikováno v:
The British Journal of Radiology
Objective: This study investigates the impact of a restricted craniocaudal (CC) field length of Methods: 110 HNC patients who underwent radical primary or adjuvant radiotherapy were retrospectively analysed. We assessed the proportion of treatment fi
Autor:
Kevin J. Harrington, Pablo Nenclares, Sheerang A. Bhide, Alan Melcher, Kate Newbold, Christopher M. Nutting, Pierre Pialat, Helena Sandoval-Insausti, Lucinda Gunn
Publikováno v:
European journal of cancer (Oxford, England : 1990). 131
Background Pre-clinical evidence suggests reduced efficacy of anticancer treatment in patients exposed to broad-spectrum antibiotics. It is hypothesised that this phenomenon may be explained by the effects of antibiotics on the composition of the mic
Autor:
Jason M. Tonne, Timothy Kottke, Richard G. Vile, Kevin J. Harrington, Laura Evgin, Adel Samson, Reuben S. Harris, Amanda L. Huff, Amy M. Molan, Christopher B. Driscoll, Phonphimon Wongthida, Hardev Pandha, Kevin G. Shim, Jill Thompson, Cynthia Wetmore, Peter Selby, Alan Melcher, Jose S. Pulido, Matthew Schuelke, Amber Miller
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
APOBEC3B, an anti-viral cytidine deaminase which induces DNA mutations, has been implicated as a mediator of cancer evolution and therapeutic resistance. Mutational plasticity also drives generation of neoepitopes, which prime anti-tumor T cells. Her
Publikováno v:
Lung cancer (Amsterdam, Netherlands). 146
Spread through air spaces (STAS) was included as a novel pattern of invasion in lung adenocarcinoma by the World Health Organization in 2015. Since then, multiple studies have investigated the association of STAS with clinicopathological and molecula
Autor:
Sarah Warren, Taha Merghoub, Michael Karin, Radek Spisek, Howard L. Kaufman, Dmitriy Zamarin, John Stagg, Daolin Tang, Timothy A. Chan, Dobrin Draganov, Kazuki Tatsuno, Aitziber Burque Martinez, Jitka Fucikova, Peter Vandenabeele, Udo S. Gaipl, Lorenzo Galluzzi, Juan José Lasarte, Karen L. Mossman, Dewan Md Sakib Hossain, George Coukos, Alessandra Cesano, Patrizia Agostinis, Silvia C. Formenti, Bryan E. Strauss, Sandy Adjemian, Encouse B. Golden, Øystein Rekdal, Guido Kroemer, Mark J. Smyth, Stefaan Van Gool, Oliver Kepp, Felipe Prosper, Sandra Demaria, Kevin J. Harrington, Ilio Vitale, Alan Melcher, Jian Han, Maria Rescigno, Richard L. Edelson, Lucia Gabriele, Sofia R. Gameiro, Gwenola Manic, Laurence Zitvogel, Takahiro Yamazaki, Sherene Loi, Eric Deutsch, James W. Hodge, Chiara Riganti, Abhishek D. Garg, Timothy M Illidge, Antonella Sistigu, Akseli Hemminki, Francesco M. Marincola, Michael T. Lotze
Publikováno v:
Journal for immunotherapy of cancer, vol 8, iss 1
JOURNAL FOR IMMUNOTHERAPY OF CANCER
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
Journal for Immunotherapy of Cancer
Galluzzi, L, Vitale, I, Warren, S, Adjemian, S, Agostinis, P, Martinez, A B, Chan, T A, Coukos, G, Demaria, S, Deutsch, E, Draganov, D, Edelson, R L, Formenti, S C, Fucikova, J, Gabriele, L, Gaipl, U S, Gameiro, S R, Garg, A D, Golden, E, Han, J, Harrington, K J, Hemminki, A, Hodge, J W, Hossain, D M S, Illidge, T, Karin, M, Kaufman, H L, Kepp, O, Kroemer, G, Lasarte, J J, Loi, S, Lotze, M T, Manic, G, Merghoub, T, Melcher, A A, Mossman, K L, Prosper, F, Rekdal, Ø, Rescigno, M, Riganti, C, Sistigu, A, Smyth, M J, Spisek, R, Stagg, J, Strauss, B E, Tang, D, Tatsuno, K, Van Gool, S W, Vandenabeele, P, Yamazaki, T, Zamarin, D, Zitvogel, L, Cesano, A & Marincola, F M 2020, ' Consensus guidelines for the definition, detection and interpretation of immunogenic cell death ', Journal for ImmunoTherapy of Cancer, vol. 8, no. 1, e000337 . https://doi.org/10.1136/jitc-2019-000337
JOURNAL FOR IMMUNOTHERAPY OF CANCER
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 1 (2020)
Journal for Immunotherapy of Cancer
Galluzzi, L, Vitale, I, Warren, S, Adjemian, S, Agostinis, P, Martinez, A B, Chan, T A, Coukos, G, Demaria, S, Deutsch, E, Draganov, D, Edelson, R L, Formenti, S C, Fucikova, J, Gabriele, L, Gaipl, U S, Gameiro, S R, Garg, A D, Golden, E, Han, J, Harrington, K J, Hemminki, A, Hodge, J W, Hossain, D M S, Illidge, T, Karin, M, Kaufman, H L, Kepp, O, Kroemer, G, Lasarte, J J, Loi, S, Lotze, M T, Manic, G, Merghoub, T, Melcher, A A, Mossman, K L, Prosper, F, Rekdal, Ø, Rescigno, M, Riganti, C, Sistigu, A, Smyth, M J, Spisek, R, Stagg, J, Strauss, B E, Tang, D, Tatsuno, K, Van Gool, S W, Vandenabeele, P, Yamazaki, T, Zamarin, D, Zitvogel, L, Cesano, A & Marincola, F M 2020, ' Consensus guidelines for the definition, detection and interpretation of immunogenic cell death ', Journal for ImmunoTherapy of Cancer, vol. 8, no. 1, e000337 . https://doi.org/10.1136/jitc-2019-000337
Cells succumbing to stress via regulated cell death (RCD) can initiate an adaptive immune response associated with immunological memory, provided they display sufficient antigenicity and adjuvanticity. Moreover, multiple intracellular and microenviro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e32760f2c469e8f3a199dc54b76b2b58
https://hdl.handle.net/10171/66750
https://hdl.handle.net/10171/66750