Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Kei Sato"'
Autor:
Doris R. Siwak, Toshimoto Kimura, Kei Sato, Hidewaki Nakagawa, Takeshi Iwaya, Masashi Fujita, Noriyuki Sasaki, Lance A. Liotta, Satoshi Nishizuka, Fumitaka Endo, Yiling Lu, Tsuyoshi Hachiya, Mizunori Yaegashi, Koki Otsuka, Tamotsu Sugai, Gordon B. Mills, Ryo Sugimoto, Zhenlin Ju
Publikováno v:
British Journal of Cancer
Background Circulating tumour DNA (ctDNA) is known as a tumour-specific personalised biomarker, but the mutation-selection criteria from heterogeneous tumours remain a challenge. Methods We conducted multiregional sequencing of 42 specimens from 14 c
Autor:
Takayuki Matsuo, Takashi Fujimoto, Shinsuke Nakagawa, Hideki Muto, Kenta Ujifuku, Hiroshi Masumoto, Yoichi Morofuji, Masami Niwa, Kei Sato
Publikováno v:
Cellular and Molecular Neurobiology. 42:997-1004
Metastatic brain tumors have poor prognoses and pose unmet clinical problems for the patients. The blood–brain barrier (BBB) implication is supposed to play a major role in brain metastasis. However, the role of pericytes remains to be elucidated i
Autor:
Ichizo Nishino, Yasuhiro Fuseya, Hirofumi Yamashita, Kei Sato, Jun-Ichi Miyahara, Seiji Kaji, Tokiko Fukuda, Takeyo Sakurai, Yoshihiko Saito, Makio Takahashi, Hideo Sugie
Publikováno v:
Internal Medicine. 59:2729-2732
Very long-chain acyl-CoA dehydrogenase (VLCAD) deficiency is a genetic disorder of fatty acid beta oxidation that is caused by a defect in ACADVL, which encodes VLCAD. The clinical presentation of VLCAD deficiency is heterogeneous, and either a delay
Reconstitution of prospermatogonial specification in vitro from human induced pluripotent stem cells
Autor:
Brian P. Hermann, Yasunari Seita, Yuka Sakata, Shinnosuke Suzuki, Kotaro Sasaki, Young Hwang, Jumpei Ito, Hirofumi Aso, Kei Sato
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Nature Communications
Nature Communications
Establishment of spermatogonia throughout the fetal and postnatal period is essential for production of spermatozoa and male fertility. Here, we establish a protocol for in vitro reconstitution of human prospermatogonial specification whereby human p
Autor:
Kenta Tane, Shoko Nakasone, Katsuya Tsuchihara, Masato Sugano, Kei Sato, Takeshi Kuwata, Tomoyuki Naito, Hibiki Udagawa, Satoshi Fujii, Keiju Aokage, Motohiro Kojima, Sachiyo Mimaki, Shinya Katsumata, Masahiro Tsuboi, Yosuke Togashi, Riu Yamashita, Atsushi Ochiai, Genichiro Ishii, Koichi Goto, Tomohiro Miyoshi
Publikováno v:
Lung Cancer. 147:12-20
Mutational signatures associated with tobacco smoking (mutational smoking signatures: SS) are characterized mainly by C A mutations. The aim of this study was to characterize the association between the tumor immune microenvironment and the SS in lun
Autor:
Yusuke Izumisawa, Takashi Murakami, Kazuya Yamaguchi, Manabu Kakizoe, Daisuke Morioka, Yoshiki Sato, Kazuya Nakagawa, Kei Sato, Satoshi Komiyama
Publikováno v:
Clinical Journal of Gastroenterology
A 63-year-old man showed massive ascites, massive pleural effusion, severe lower-extremity edema, and repeated esophageal variceal bleeding. Two-year previously, he received 13-courses of oxaliplatin-based chemotherapy (OBC) followed by associating l
Autor:
Masafumi Nishizawa, Akihiro Kawashima, Kei Sato, Yoshiaki Kubota, Keita Negishi, Jun Nakazato, Hiromitsu Sekizuka, Toshikazu Hashizume, Mitsuyoshi Yamamoto, Satoshi Hoshide, Norihiro Tsuchiya, Keisuke Narita, Kazuomi Kario, Yumiko Fujita, Hideyasu Abe, Tetsuro Yoshida, Kayo Yamagiwa, Yasuhisa Abe, Takeshi Fujiwara, Tomoyuki Kabutoya, Yoshio Matsui
Publikováno v:
J Clin Hypertens (Greenwich)
Vascular biomarkers, including the cardio‐ankle vascular index (CAVI), are increasingly being recognized as important indicators of cardiovascular risk. CAVI has been shown to have good discriminative ability for detecting new‐onset hypertension,
Autor:
Masahide Yoshida, Tadashi Kimura, Azusa Ichino-Yamashita, Kei Sato, Yukihiko Sugimoto, Katsuhiko Nishimori, Yuki Takayanagi
Publikováno v:
Endocrinology
Parturition is an essential process in placental mammals for giving birth to offspring. However, the molecular machineries of parturition are not fully understood. We investigated whether oxytocin plays a crucial role in the progress of parturition i
Autor:
Yoriyuki Konno, Keiya Uriu, So Nakagawa, Kei Sato, Izumi Kimura, Daniel Sauter, Kristina Hopfensperger
Publikováno v:
Cell Reports
Cell Reports, Vol 34, Iss 13, Pp 108916-(2021)
Cell Reports, Vol 34, Iss 13, Pp 108916-(2021)
The presence of an ORF6 gene distinguishes sarbecoviruses such as SARS-CoV and SARS-CoV-2 from other betacoronaviruses. Here, we show that ORF6 inhibits the induction of innate immune signaling including upregulation of type I IFN upon viral infectio
Autor:
Kai Ninomiya, Satoru Kishi, Daijiro Tomii, Jiro Aoki, Taishi Okuno, Tetsu Tanaka, Kazuyuki Yahagi, Kei Sato, Kota Komiyama, Yu Sato, Keita Koseki, Kengo Tanabe, Hideki Koike
Publikováno v:
Atherosclerosis. 287:155-161
Obesity is a risk factor for coronary artery disease (CAD), but the association between fat distribution, i.e., visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT), and coronary artery plaque morphology remains unclear. This study exp