Zobrazeno 1 - 10
of 16
pro vyhledávání: '"John M. Higgins"'
Autor:
Marie-France Hivert, P. Kaitlyn Edelson, Jessica Sheehan Tangren, Melody Cayford, Aaron Leong, David M. Nathan, Sarah N. Bernstein, Kaitlyn E. James, Juliana Arenas, Michael J. Callahan, Camille E. Powe, John M. Higgins
Publikováno v:
J Clin Endocrinol Metab
ObjectiveTo characterize the relationship between hemoglobin A1c (HbA1c) levels and glucose tolerance across pregnancy and postpartum.Design and ParticipantsIn a longitudinal study of pregnant women with gestational diabetes risk factors (N = 102), w
Publikováno v:
Br J Haematol
Sickle cell trait (SCT) is the benign heterozygous carrier state for the sickle variant of the HBB gene. Most of the ~300 million people with SCT worldwide will not experience any significant complications. However, accumulating evidence finds SCT as
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 104:707-710
Commentary placing genetic ancestry markers and racial difference in HbA1c in the context of more common variations in the HbA1c-average glucose relationship and their clinical implications.
Publikováno v:
Annual review of pathology. 15
Modeling has enabled fundamental advances in our understanding of the mechanisms of health and disease for centuries, since at least the time of William Harvey almost 500 years ago. Recent technological advances in molecular methods, computation, and
Autor:
Gregory R. Wojtkiewicz, Sebastian Cremer, Maximilian J. Schloss, Ralph Weissleder, Matthias Nahrendorf, Stephen D. Schmidt, Paolo Fumene Feruglio, Brody H. Foy, Filip K. Swirski, Shuang Zhang, Maarten Hulsmans, Claudio Vinegoni, David Rohde, John M. Higgins
Background Recurrent myocardial infarction (MI) is common in patients with coronary artery disease and is associated with high mortality. Long-term reprogramming of myeloid progenitors occurs in response to inflammatory stimuli and alters the organis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4560f03f6dfbf3151e7bd8d2ff5b471
http://hdl.handle.net/11562/1012753
http://hdl.handle.net/11562/1012753
Publikováno v:
eLife
eLife, Vol 8 (2019)
eLife, Vol 8 (2019)
Low blood count is a fundamental disease state and is often an early sign of illnesses including infection, cancer, and malnutrition, but our understanding of the homeostatic response to blood loss is limited, in part by coarse interpretation of bloo
Autor:
John M. Higgins, Richard M. Bergenstal, Ionut Bebu, Claire Lund, Valerie L. Arends, Mary E. Larkin, Heidi Krause-Steinrauf, Robert M. Cohen, Mary L. Johnson, Margaret Tiktin, David M. Nathan, William H. Herman
Publikováno v:
Diabetes Technol Ther
Background: The Glycemia Reduction Approaches in Diabetes: A Comparative Effectiveness (GRADE) study has enrolled a racially and ethnically diverse population with type 2 diabetes, performed extensive phenotyping, and randomly assigned the participan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5f2c2dd364539a043430bfa6bf5fed2
https://europepmc.org/articles/PMC7207016/
https://europepmc.org/articles/PMC7207016/
Publikováno v:
American journal of hematologyREFERENCES. 95(3)
Iron-deficiency contributes to a ∼50% of anemia prevalence worldwide, but reference intervals for iron status tests are not optimized for anemia diagnosis. To address this limitation, we identified the serum ferritin (SF) thresholds associated with
Publikováno v:
Transfusion. 57:1930-1937
BACKGROUND Alloimmunization to red blood cells (RBCs) can cause serious transfusion reactions and complicate the search for compatible blood products. Alloantibodies can be detected for periods ranging from a few days to several years, yet the mechan
Publikováno v:
Clin Chem
Background Many clinical decisions depend on estimating patient risk of clinical outcomes by interpreting test results relative to reference intervals, but standard application of reference intervals suffers from two major limitations that reduce the