Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Cathy S. Wang"'
Autor:
George Tang, Eric Sanchez, James R. Berenson, Abigail Gillespie, Cathy S Wang, Mingjie Li, Haiming Chen
Publikováno v:
Leukemia Research. 57:45-54
Oprozomib (OPZ or ONYX 0912) is an irreversible, orally administered proteasome inhibitor (PI) and an analog of carfilzomib. We set out to determine the anti-angiogenic effect of OPZ using the choriollantoic membrane/feather bud (CAM/FB) model and it
Autor:
Haiming Chen, Tiffany Lee, Colin Xie, Kyle Udd, Cathy S Wang, Kevin DeCorso, Jasmin Cao, Eric Sanchez, Tanya M. Spektor, Christian E. Casas, James R. Berenson, Camilia Soof, Mingjie Li, George Tang
Publikováno v:
Molecular Cancer Research. 15:598-609
TNF receptor–associated factor 6 (TRAF6) has been implicated in polyubiquitin-mediated IL1R/TLR signaling through activation of IκB kinase (IKK) to regulate the NF-κB and JNK signaling pathways. Here, TRAF6 protein was determined to be overexpres
Serum B-cell maturation antigen: a novel biomarker to predict outcomes for multiple myeloma patients
Autor:
Michael Ghermezi, Suzie Vardanyan, Claudia Andreu-Vieyra, Sophia Petraki, Kyle Udd, Cathy S Wang, Regina A. Swift, Tanya M. Spektor, Nika M Harutyunyan, Mingjie Li, Eric Sanchez, Jillian Gottlieb, James R. Berenson, Ariana Berenson, Haiming Chen
Publikováno v:
Haematologica
B-cell maturation antigen is expressed on plasma cells. In this study, we have identified serum B-cell maturation antigen as a novel biomarker that can monitor and predict outcomes for multiple myeloma patients. Compared to healthy donors, patients w
Autor:
Suzie Vardanyan, George Tang, Abigail Gillespie, Cathy S Wang, Nika M Harutyunyan, Eric Sanchez, James R. Berenson, Morgan Ferros, Haiming Chen, Jillian Gottlieb, Mingjie Li
Publikováno v:
Clinical Cancer Research. 22:3383-3397
Purpose: Reduced uninvolved immunoglobulin (Ig) levels are a hallmark of multiple myeloma. We previously showed that B-cell maturation antigen (BCMA) is solubilized and at high levels in multiple myeloma patient serum. We hypothesize that soluble BCM
Autor:
Eric Sanchez, James R. Berenson, Aleksandra Vidisheva, Mingjie Li, George Tang, Tara Hekmati, Gabriel N. Waterman, Cathy S Wang, Camilia Soof, Saurabh Patil, Edward J Tanenbaum, Haiming Chen
Publikováno v:
Expert review of molecular diagnostics. 18(4)
B-cell maturation antigen (BCMA) is a cell membrane bound tumor necrosis factor receptor family member that is expressed exclusively on late stage normal and malignant B-cells and plasma cells. Addition of two of its ligands, B-cell activating factor
Autor:
Remy E Schlossberg, George Tang, Autumn L Porter, Edward J Tanenbaum, Moryel A Yashar, Tara Hekmati, Camilia Soof, Eric Sanchez, James R. Berenson, Cathy S Wang, Haiming Chen, Mingjie Li, Saurabh Patil, Emily J Smith
Publikováno v:
Targeted oncology. 13(1)
B-cell maturation antigen (BCMA) was originally identified as a cell membrane receptor, expressed exclusively on late stage B-cells and plasma cells (PCs). Investigations of BCMA as a target for therapeutic intervention in multiple myeloma (MM) were
Autor:
Brian Zahab, Haiming Chen, Nicole Ng, Sean Bujarski, Cathy S Wang, Edward J Tanenbaum, George Tang, Ning Xu, Jasmin Cao, Tara Hekmati, Eric Sanchez, James R. Berenson, Mingjie Li, Camilia Soof
Publikováno v:
Blood. 132:1910-1910
Introduction: Ruxolitinib (RUX) is an inhibitor of the Janus kinase family of protein tyrosine kinases (JAKs) that is effective for the treatment of myeloproliferative diseases. Immunomodulatory drugs including lenalidomide (LEN) and corticosteroids
Autor:
Saurabh Patil, Eric Sanchez, James R. Berenson, Camilia Soof, Regina A. Swift, Kian J. Rahbari, Haiming Chen, Marsiye Emamy-Sadr, Sean Bujarski, Cathy S Wang, Tanya M. Spektor, Mingjie Li
Publikováno v:
Blood. 132:1894-1894
Background: B-cell maturation antigen (BCMA) is highly expressed on malignant plasma cells from patients with multiple myeloma (MM). We have previously shown that serum (s) BCMA levels are elevated among MM patients, and baseline levels predict both
Autor:
Kyle Udd, George Tang, Christian E. Casas, Cathy S Wang, Kevin DeCorso, Jessica Wang, Mingjie Li, Jasmin Cao, Tara Hekmati, Eric Sanchez, James R. Berenson, Camilia Soof, Haiming Chen
Publikováno v:
Blood. 128:5641-5641
Introduction: B-cell maturation antigen (BCMA) has been shown to be highly expressed on the surface of tumor cells from patients (pts) with multiple myeloma (MM) and chronic lymphocytic leukemia (CLL) and is the target for therapeutic approaches in t