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pro vyhledávání: '"Alf Kozian"'
Autor:
Anders Larsson, João Batista Borges, Thomas Hachenberg, Moritz Kretzschmar, Thomas F. Schilling, Alf Kozian, James E. Baumgardner, Göran Hedenstierna
Publikováno v:
Anesthesiology. 127:800-812
BackgroundIncreasing numbers of patients with obstructive lung diseases need anesthesia for surgery. These conditions are associated with pulmonary ventilation/perfusion (VA/Q) mismatch affecting kinetics of volatile anesthetics. Pure shunt might del
Autor:
Thomas Schilling, Thomas Hachenberg, James E. Baumgardner, Alf Kozian, Jens Schreiber, Göran Hedenstierna, Moritz Kretzschmar, Anders Larsson
Publikováno v:
Respiratory Physiology & Neurobiology. 220:88-94
Bronchoconstriction is a hallmark of asthma and impairs gas exchange. We hypothesized that pharmacokinetics of volatile anesthetics would be affected by bronchoconstriction. Ventilation/perfusion (VA/Q) ratios and pharmacokinetics of desflurane in bo